Invention Grant
- Patent Title: PHA-producing microorganism in which glycerol kinase activity is enhanced, and PHA production method using same
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Application No.: US16616276Application Date: 2018-05-23
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Publication No.: US11268113B2Publication Date: 2022-03-08
- Inventor: Rina Aoki , Shunsuke Sato
- Applicant: KANEKA CORPORATION
- Applicant Address: JP Osaka
- Assignee: KANEKA CORPORATION
- Current Assignee: KANEKA CORPORATION
- Current Assignee Address: JP Osaka
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JPJP2017-103343 20170525
- International Application: PCT/JP2018/019815 WO 20180523
- International Announcement: WO2018/216726 WO 20181129
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12P7/62 ; C12N9/10 ; C12N15/74 ; C12P7/625

Abstract:
Provided are a PHA-producing microorganism producing a higher molecular weight PHA and a PHA production method using the PHA-producing microorganism. A PHA-producing microorganism including a gene encoding a PHA synthase derived from genus Aeromonas, in which at least a portion of a PHA degrading enzyme gene is altered by substitution, deletion, insertion, and/or addition to reduce or eliminate activity of a PHA degrading enzyme encoded by the gene, and further a glycerol kinase activity is enhanced.
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