发明授权
US5342774A Nucleotide sequence encoding the tumor rejection antigen precursor,
MAGE-1
失效
编码肿瘤排斥抗原前体MAGE-1的核苷酸序列
- 专利标题： Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1
- 专利标题（中）： 编码肿瘤排斥抗原前体MAGE-1的核苷酸序列
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申请号： US807043申请日： 1991-12-12
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公开(公告)号： US5342774A公开(公告)日： 1994-08-30
- 发明人: Thierry Boon , Pierre van der Bruggen , Benoit Van den Eynde , Aline Van Pel , Etienne De Plaen , Christophe Lurquin , Patrick Chomez , Catia Traversari
- 申请人： Thierry Boon , Pierre van der Bruggen , Benoit Van den Eynde , Aline Van Pel , Etienne De Plaen , Christophe Lurquin , Patrick Chomez , Catia Traversari
- 申请人地址： NY New York
- 专利权人： Ludwig Institute for Cancer Research
- 当前专利权人： Ludwig Institute for Cancer Research
- 当前专利权人地址： NY New York
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; A61K9/127 ; A61K35/12 ; A61K35/14 ; A61K35/18 ; A61K38/00 ; A61K39/00 ; A61K39/395 ; A61K48/00 ; A61P35/00 ; C07K7/06 ; C07K14/00 ; C07K14/47 ; C07K14/52 ; C07K14/525 ; C07K14/54 ; C07K14/55 ; C07K14/705 ; C07K16/00 ; C07K16/30 ; C07K16/42 ; C07K17/00 ; C12N1/00 ; C12N1/20 ; C12N1/21 ; C12N5/10 ; C12N7/00 ; C12N15/00 ; C12N15/02 ; C12N15/09 ; C12N15/12 ; C12P21/02 ; C12P21/08 ; C12Q1/00 ; C12Q1/68 ; C12R1/19 ; G01N33/50 ; G01N33/53 ; G01N33/574 ; G01N33/577 ; G01N33/68 ; C07H15/12 ; C07K3/00 ; C12N1/16 ; C12N1/18 ; C12N5/00 ; C12P19/34
摘要：
The invention relates to an isolated DNA sequence which codes for an antigen expressed by tumor cells which is recognized by cytotoxic T cells, leading to lysis of the tumor which expresses it. Also described are cells transfected by the DNA sequence, and various therapeutic and diagnostic uses arising out of the properties of the DNA and the antigen for which it codes.
公开/授权文献
- US5856131A Human selenoprotein 公开/授权日：1999-01-05
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