发明授权
- 专利标题: Osteogenic growth polypeptides identified from regenerating bone marrow
- 专利标题(中): 从再生骨髓鉴定的成骨生长多肽
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申请号: US79637申请日: 1993-06-18
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公开(公告)号: US5461034A公开(公告)日: 1995-10-24
- 发明人: Gideon A. Rodan , John W. Jacobs , Mohinder K. Sardana , Dan Gazit , Michael Chorev , Andras Muhlrad , Arye Shteyer , Nura Mansur , Zvi Greenberg , Shimon Slavin , Olga Gurevitch , Itai A. Bab
- 申请人: Gideon A. Rodan , John W. Jacobs , Mohinder K. Sardana , Dan Gazit , Michael Chorev , Andras Muhlrad , Arye Shteyer , Nura Mansur , Zvi Greenberg , Shimon Slavin , Olga Gurevitch , Itai A. Bab
- 申请人地址: ILX Jerusalem
- 专利权人: Yissum Research Development Company of the Hebrew University of Jerusalem
- 当前专利权人: Yissum Research Development Company of the Hebrew University of Jerusalem
- 当前专利权人地址: ILX Jerusalem
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/51 ; A61K38/08 ; A61F2/02 ; A61K35/32 ; A61K38/39
摘要:
A biochemically pure polypeptide(s), termed osteogenic growth polypeptide (OGP), which exhibits stimulatory effects on osteoblastic cells, in vivo bone formation and hemopoietic reconstruction. OGP, identified from regenerating bone marrow, has an amino acid sequence ofAla-Leu-Lys-Arg-Gln-Gly-Arg-Thr-Leu-Tyr-Gly-Phe-Gly-Gly.
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