-
1.
公开(公告)号:US5461034A
公开(公告)日:1995-10-24
申请号:US79637
申请日:1993-06-18
申请人: Gideon A. Rodan , John W. Jacobs , Mohinder K. Sardana , Dan Gazit , Michael Chorev , Andras Muhlrad , Arye Shteyer , Nura Mansur , Zvi Greenberg , Shimon Slavin , Olga Gurevitch , Itai A. Bab
发明人: Gideon A. Rodan , John W. Jacobs , Mohinder K. Sardana , Dan Gazit , Michael Chorev , Andras Muhlrad , Arye Shteyer , Nura Mansur , Zvi Greenberg , Shimon Slavin , Olga Gurevitch , Itai A. Bab
CPC分类号: C07K14/51 , A61K38/00 , Y10S530/84 , Y10S530/841
摘要: A biochemically pure polypeptide(s), termed osteogenic growth polypeptide (OGP), which exhibits stimulatory effects on osteoblastic cells, in vivo bone formation and hemopoietic reconstruction. OGP, identified from regenerating bone marrow, has an amino acid sequence ofAla-Leu-Lys-Arg-Gln-Gly-Arg-Thr-Leu-Tyr-Gly-Phe-Gly-Gly.
摘要翻译: 称为成骨生长多肽(OGP)的生物化学纯多肽,其对成骨细胞表现出刺激作用,体内骨形成和造血重建。 由再生骨髓鉴定的OGP具有Ala-Leu-Lys-Arg-Gln-Gly-Arg-Thr-Leu-Tyr-Gly-Phe-Gly-Gly的氨基酸序列。