发明授权
US5614619A Secondary-metabolite biosynthesis genes from actinomycetes, method of
isolating them and their use
失效
来自放线菌的次生代谢物生物合成基因，分离方法及其应用
- 专利标题： Secondary-metabolite biosynthesis genes from actinomycetes, method of isolating them and their use
- 专利标题（中）： 来自放线菌的次生代谢物生物合成基因，分离方法及其应用
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申请号： US196218申请日： 1994-08-25
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公开(公告)号： US5614619A公开(公告)日： 1997-03-25
- 发明人: Wolfgang Piepersberg , Michael Stockmann , Kambiz M. Taleghani , J urgen Distler , Susanne Grabley , Petra Sichel , Barbara Br au
- 申请人： Wolfgang Piepersberg , Michael Stockmann , Kambiz M. Taleghani , J urgen Distler , Susanne Grabley , Petra Sichel , Barbara Br au
- 申请人地址： DEX Frankfurt am Main
- 专利权人： Hoechst Aktiengesellschaft
- 当前专利权人： Hoechst Aktiengesellschaft
- 当前专利权人地址： DEX Frankfurt am Main
- 优先权： DEX4130967.7 19910918
- 主分类号： C07K14/195
- IPC分类号： C07K14/195 ; C07K14/00 ; C07K14/41 ; C12N9/10 ; C12N9/12 ; C12N9/92 ; C12N15/09 ; C12N15/52 ; C12N15/54 ; C12N15/61 ; C12P19/62 ; C12P21/02 ; C12Q1/68 ; C12R1/545 ; C07H21/04
摘要：
Secondary-metabolite biosynthesis genes from actinomycetes, method of isolating them, and their use.The invention concerns secondary-metabolite biosynthesis genes from actinomycetes, a method of isolating secondary-metabolite and, in particular, 6-deoxy-sugar biosynthesis genes, from actinomycetes using the gene probes strD, strE, strL and strM gene probes from Streptomyces griseus DSM40236, and structurally related genes, as gene probes for detecting the genes snoT (coding for amphotheronolide B-dTDP-D-mycosaminyl transferase), snoD (coding for dTDP-D-glucose synthase) and snoM (coding for dTDP-4-keto-6-deoxy-D-glucose isomerase), or one or more secondary-metabolite biosynthesis genes from actinomycetes. The invention also concerns the use of secondary-metabolite biosynthesis genes thus isolated.
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