发明授权
- 专利标题: Calcium receptor modulating agents
- 专利标题(中): 钙受体调节剂
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申请号: US10444946申请日: 2003-05-22
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公开(公告)号: US06908935B2公开(公告)日: 2005-06-21
- 发明人: Michael G. Kelly , Shimin Xu , Ning Xi , Philip Miller , John F. Kincaid , Chiara Ghiron , Thomas Coulter
- 申请人: Michael G. Kelly , Shimin Xu , Ning Xi , Philip Miller , John F. Kincaid , Chiara Ghiron , Thomas Coulter
- 申请人地址: US CA Thousand Oaks
- 专利权人: Amgen Inc.
- 当前专利权人: Amgen Inc.
- 当前专利权人地址: US CA Thousand Oaks
- 代理商 Mary Susan Howard; Ron K. Levy; Stuart L. Watt
- 主分类号: A61K31/137
- IPC分类号: A61K31/137 ; A61K31/145 ; A61K31/167 ; A61K31/275 ; A61K31/341 ; A61K31/357 ; A61K31/36 ; A61K31/381 ; A61K31/4045 ; A61K31/417 ; A61K31/4184 ; A61K31/42 ; A61K31/423 ; A61K31/426 ; A61K31/4418 ; A61K31/443 ; A61K31/4439 ; A61K31/4465 ; A61K31/47 ; A61K31/4965 ; A61K31/50 ; A61K31/505 ; A61K31/52 ; A61K31/5377 ; A61P3/14 ; A61P5/18 ; A61P5/20 ; A61P19/10 ; C07B53/00 ; C07C209/28 ; C07C211/27 ; C07C211/29 ; C07C211/30 ; C07C211/55 ; C07C215/46 ; C07C217/54 ; C07C217/58 ; C07C229/38 ; C07C233/43 ; C07C235/20 ; C07C237/30 ; C07C255/58 ; C07C255/59 ; C07C275/40 ; C07C311/08 ; C07C317/32 ; C07D207/26 ; C07D207/32 ; C07D207/325 ; C07D209/08 ; C07D209/10 ; C07D209/44 ; C07D211/22 ; C07D211/26 ; C07D211/70 ; C07D213/26 ; C07D213/30 ; C07D213/38 ; C07D213/61 ; C07D213/62 ; C07D213/64 ; C07D213/65 ; C07D213/68 ; C07D213/73 ; C07D213/74 ; C07D213/75 ; C07D213/82 ; C07D215/12 ; C07D231/56 ; C07D233/22 ; C07D235/06 ; C07D235/08 ; C07D235/10 ; C07D235/12 ; C07D235/14 ; C07D237/14 ; C07D239/26 ; C07D239/34 ; C07D239/42 ; C07D239/47 ; C07D241/12 ; C07D241/42 ; C07D249/18 ; C07D261/08 ; C07D263/32 ; C07D263/56 ; C07D271/06 ; C07D271/10 ; C07D271/12 ; C07D277/24 ; C07D277/28 ; C07D277/40 ; C07D277/42 ; C07D277/66 ; C07D277/78 ; C07D285/00 ; C07D285/01 ; C07D295/096 ; C07D295/135 ; C07D295/185 ; C07D295/26 ; C07D307/42 ; C07D307/52 ; C07D307/68 ; C07D317/46 ; C07D317/54 ; C07D317/58 ; C07D319/18 ; C07D321/10 ; C07D333/16 ; C07D333/20 ; C07D333/56 ; C07D401/12 ; C07D405/12 ; C07D471/04 ; C07D473/00 ; C07D487/04
摘要:
The compounds of the invention are represented by the following general structure or a pharmaceutically acceptable salt thereof, and compositions containing them, wherein the variables are defined herein, and their use to reduce or inhibit PTH secretion, including methods for reducing or inhibiting PTH secretion and methods for treatment or prophylaxis of diseases associated with bone disorders, such as osteoporosis, or associated with excessive secretion of PTH, such as hyperparathyroidism. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
公开/授权文献
- US20040082625A1 Calcium receptor modulating agents 公开/授权日:2004-04-29
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