发明授权
US08765119B2 Treating amyotrophic lateral sclerosis (ALS)with isolated aldehyde dehydrogenase-positive umbilical cord blood cells
有权
用分离的醛脱氢酶阳性脐带血细胞治疗肌萎缩性侧索硬化（ALS）
- 专利标题： Treating amyotrophic lateral sclerosis (ALS)with isolated aldehyde dehydrogenase-positive umbilical cord blood cells
- 专利标题（中）： 用分离的醛脱氢酶阳性脐带血细胞治疗肌萎缩性侧索硬化（ALS）
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申请号： US10908322申请日： 2005-05-06
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公开(公告)号： US08765119B2公开(公告)日： 2014-07-01
- 发明人: Svitlana Garbuzova-Davis , Andrew Balber , Cyndy Davis-Sanberg , Tracy Gentry , Nicole Kuzmin-Nichols , Paul R Sanberg , Alison Willing
- 申请人： Svitlana Garbuzova-Davis , Andrew Balber , Cyndy Davis-Sanberg , Tracy Gentry , Nicole Kuzmin-Nichols , Paul R Sanberg , Alison Willing
- 申请人地址： US FL Tampa US FL Tampa US NC Durham
- 专利权人： University of South Florida,Saneron CCEL Therapeutics, Inc.,StemCo Biomedical, Inc.
- 当前专利权人： University of South Florida,Saneron CCEL Therapeutics, Inc.,StemCo Biomedical, Inc.
- 当前专利权人地址： US FL Tampa US FL Tampa US NC Durham
- 代理机构： Smith & Hopen, P.A.
- 代理商 Robert J. Varkonyi
- 主分类号： A01N63/00
- IPC分类号： A01N63/00 ; A61K35/28 ; A61K35/48 ; A61K35/12 ; A61K35/50 ; A61K35/30 ; A61K9/00 ; C12N5/0789 ; C12N5/071 ; C12N5/074 ; C12N5/0775
摘要：
A method of treating a patient with a neurodegenerative disease, such as ALS, using progenitor cells isolated from human umbilical cord blood. Non-invasive transplantation of aldehyde dehydrogenase (ALDH+) expressing progenitor cells provides cell replacement and protection of motor neurons.
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