Described are sample carriers and methods of extracting a fluid sample from a dried sample on a sample carrier. The sample carrier has a first carrier portion that receives a fluid sample, and includes a material that adsorbs the fluid sample and dissolves upon application of a solvent. A second carrier portion is attached to the first carrier portion and includes a material that is indissolvable in the solvent. The first carrier portion having a dried sample is dissolved into a solution upon application of the solvent. The solution can be analyzed to determine constituents in the extracted sample. The sample carrier can conveniently be in the form of a card or a dipstick. In alternative embodiments, a carrier portion that includes the dried sample is indissolvable in the solvent but is released from another carrier portion through application of a solvent to an intervening dissolvable carrier portion.