摘要:
A medical device is presented for use in tissue characterization and treatment. The device comprises a tissue characterization probe comprising: a tissue characterization probe comprising an elongated carrier carrying an array of tissue characterization sensors, each configured and operable for generates a tissue characterization signal corresponding to a tissue mass at a location of the respective sensor, said tissue characterization sensors being arranged in a spaced-apart relationship along at least a longitudinal axis of said carrier within at least a distal portion of the carrier with known distances between them, such that during progression of the probe through a tissue mass each of the sensors generates tissue characterization signals from successive locations thereof within the tissue mass thereby enabling to locate, and optionally also determine a dimension of, a tissue specimen inside said tissue mass based on the characterization signals from the sensors in the array. The elongated carrier has two integral portions including said distal portion and a hollow portion extending between a proximal end of the carrier and said distal portion. The carrier is configured for passing a treatment tool through the hollow portion thereof and enabling at least a part of the treatment tool to project from the hollow portion and extend along the distal portion. The device thereby enables consequent treatment of a tissue specimen by a treatment tool when mounted on the carrier. Several movement mechanisms are described for enabling relative movement between the carrier and a treatment tool passing therethrough.
摘要:
Biopsy devices are presented comprising: an inner needle comprising a tip for piercing tissue, and a cavity for receiving a tissue portion; an outer sheath moving with respect to the inner needle between a forward position of the sheath in which it totally covers the cavity and a backward position in which the cavity is totally uncovered, the outer sheath comprising a cutting edge at its front end configured to cut the tissue portion into the cavity while moving in a forward direction; and at least one of: a sensing unit mounted on the outer sheath such that the sensing unit is aligned with the cavity when the sheath is in the forward position to thereby sense tissue signals from the tissue portion; or a suction system for applying suction force in the cavity to pull the tissue portion into the cavity while the sheath moves in a backward direction.
摘要:
A device for substance-characterization, designed for effective sensor-to-substance contact, includes an element, having a rigid surface, on which at least one sensor is arranged, and a mechanism for causing a force to be applied to a soft, pliable substance, the line of force being at a sharp angle with the rigid surface, for stretching or stretching and pushing the soft substance against the rigid surface, thus achieving effective contact between the substance and the at least one sensor. In consequence, the accuracy of the sensing is improved. In accordance with another embodiment, a plurality of sensors is employed, arranged along a curved element, for providing three-dimensional information regarding the substance, for example, by small-scale computerized tomography. Alternatively, the device comprises a structure; a first mechanism, configured for exerting a first force on a substance, for fixing the substance to the structure, so as to substantially immobilize the substance; and a second mechanism, configured for pressing at least one sensor against an external surface of the immobilized substance, thereby exerting a second force on the immobilized substance, wherein at least a component of the first force is in opposition to at least a component of the second force, forcing the immobilized substance against the at least one sensor, and forcing the at least one sensor against the immobilized substance, bringing about an effective contact between the at least one sensor and the immobilized substance. The substance may be tissue, ex-vivo or in situ, or a biopsy sample. Alternatively, it may be another soft, pliable substance, such as hydrogel or an elastomer.
摘要:
A sensor for tissue characterization is provided, comprising: a resonator, configured to be placed proximally to an edge of a tissue for characterization, without penetrating the tissue, the resonator comprising a conductive structure associated with a diameter-equivalent dimension D, in a plane substantially parallel with the edge, and with a feature size d; and at least one conductive lead, for providing communication with an external system, wherein the resonator is configured to resonate at a frequency which corresponds to a free-air wavelength range of between about lambda and about 40lambda, wherein lambda is at least about ten times the diameter-equivalent D, and wherein upon receiving a signal in the range of between about lambda and about 40lambda, the sensor is configured to induce electric and magnetic fields, in a near zone, in the tissue, the near zone having a diameter of about D, so that the tissue in the near zone effectively functions as part of the resonator, influencing its resonating values, and so the tissue in the near zone is thereby characterized by its electromagnetic properties, by the resonating response of the resonator.
摘要:
A sensor unit for use in measurements on a subject is presented. The sensor unit includes a near field electromagnetic sensor and a flexible signal transmission structure, which are integral with one another by means of at least one common continuous surface. The flexible signal transmission structure is constructed from a first layer including signal connection lines associated with sensor cells near field electromagnetic sensor and a second electrically conductive layer electrically coupled to the electrically conductive material of the sensor.
摘要:
A graphical user interface (GUI) including: (a) a group definition module adapted to accept a user input defining groups; (b) a data receiver operable to receive a plurality of individual measurement input datum indicative of status of a substrate; (c) a grouping module configured to assign each of said individual measurement input datum to one of said groups to produce grouped data; and (d) an output module adapted to output the grouped data.
摘要:
An integrated tool is provided, having a tissue-type sensor, for determining the tissue type at a near zone volume of a tissue surface, an a distance-measuring sensor, for determining the distance to an interface with another tissue type, for (i) confirming an existence of a clean margin of heathy tissue around a mailignant tumor, which is being removed, and (ii) determining the depth of the clean margin. The integrated tool may further include a position tracking device and an incision instrument. The soft tissue may be held within a fix frame, while the tumor is being removed.
摘要:
A measurement device is presented being configured to be connectable to an analyzer unit (including a network analyzer). The measurement device includes a measuring unit and a calibration and control unit connected to and integral with the measuring unit. The calibration and control unit is configured to enable connection of the measuring unit to the analyzer unit. The calibration and control unit includes a number of terminals of known RF reflection coefficients respectively and includes a memory utility carrying recorded data indicative of said RF reflection coefficients and recorded data indicative of RF transfer coefficients of the calibration and control unit. This configuration enables calculation of the RF response of the measuring unit while remaining integral with the calibration and control unit.