公开(公告)号：EP3269402A1

公开(公告)日：2018-01-17

申请号：EP16761714.1

申请日：2016-03-07

申请人： The Chemo-Sero-Therapeutic Research Institute ,  Adeka Corporation ,  National University Corporation Tokyo Medical and Dental University ,  Sapporo Medical University

发明人： SAGA, Hideki ,  UCHIDA, Takanori ,  TOKOROZAKI, Shoko ,  HIWATARI, Ken-Ichiro ,  OBARA, Haruki ,  KISHIDA, Akio ,  KIMURA, Tsuyoshi ,  NEGISHI, Jun ,  HIGAMI, Tetsuya ,  FUNAMOTO, Seiichi

IPC分类号： A61L31/00

CPC分类号： A61L31/046 ,  A61L24/106 ,  A61L31/005 ,  A61L31/10 ,  A61L2300/424

摘要： An anti-adhesion material comprising decellularized tissues and a biocompatible polymer or fibrin glue; a method for preparing an anti-adhesion material comprising complexing a biocompatible polymer or fibrin glue to decellularized tissues; an anti-adhesion material kit comprising decellularized tissues and a biocompatible polymer or fibrin glue; a substitute biomembrane comprising decellularized tissues and a biocompatible polymer or fibrin glue; a method for preparing a substitute biomembrane comprising complexing a biocompatible polymer or fibrin glue to decellularized tissues; and a substitute biomembrane kit comprising decellularized tissues and a biocompatible polymer or fibrin glue.

摘要翻译： 包含脱细胞组织和生物相容性聚合物或纤维蛋白胶的抗粘连材料; 制备抗粘连材料的方法，所述方法包括将生物相容性聚合物或纤维蛋白胶与脱细胞组织复合; 包含脱细胞组织和生物相容性聚合物或纤维蛋白胶的抗粘连材料试剂盒; 包含去细胞组织和生物相容性聚合物或纤维蛋白胶的替代生物膜; 制备替代生物膜的方法，其包括将生物相容性聚合物或纤维蛋白胶与脱细胞组织复合; 以及包含去细胞组织和生物相容性聚合物或纤维蛋白胶的替代生物膜试剂盒。

公开(公告)号：EP2944330A1

公开(公告)日：2015-11-18

申请号：EP13871129.6

申请日：2013-12-17

申请人： The Chemo-Sero-Therapeutic Research Institute

发明人： SHINYA, Noriko ,  UCHIDA, Takanori ,  KISHIDA, Akio ,  HIGAMI, Tetsuya

IPC分类号： A61L27/00 ,  A61F2/06

CPC分类号： A61F2/82 ,  A61F2/06 ,  A61F2/062 ,  A61F2230/0069 ,  A61F2240/002 ,  A61L27/3625 ,  A61L27/3683 ,  A61L27/507 ,  A61L27/54 ,  A61L2300/252 ,  Y10T156/1038 ,  A61L27/34 ,  C08L89/00

摘要： An artificial blood vessel that can be transplanted to blood vessels with a small diameter, can be adjusted to an arbitrary size of a diameter, improves in invasiveness when a graft is taken, and overcomes the problem on the provision of a graft is provided. An artificial blood vessel prepared from a decellularized tubular structure, which is prepared by processing a decellularized, sheet-like blood vessel (decellularized blood vessel sheet) into a roll structure, and a tissue adhesive, wherein a portion which is contacted with blood that flows within the artificial blood vessel consists of the tissue of the tunica intima lined with the tissue of the tunica media whereas a portion of the sheet that overlaps when the sheet is processed into a roll structure (overlap width) consists of the tissue of the tunica media and wherein a tissue adhesive is applied to the overlap width.

公开(公告)号：EP2995326A1

公开(公告)日：2016-03-16

申请号：EP14795291.5

申请日：2014-05-02

申请人： The Chemo-Sero-Therapeutic Research Institute ,  National University Corporation Tokyo Medical and Dental University ,  Sapporo Medical University ,  ADEKA CORPORATION

发明人： MATSUDA, Junichi ,  MIYABASHIRA, Sumika ,  HARANO, Satomi ,  KISHIDA, Akio ,  KIMURA, Tsuyoshi ,  NEGISHI, Jun ,  HIGAMI, Tetsuya ,  FUNAMOTO, Seiichi ,  HIWATARI, Ken-ichiro ,  TASAKI, Akiko

IPC分类号： A61L27/00 ,  A61K9/06 ,  A61K35/12 ,  A61K35/28 ,  A61K35/30 ,  A61K35/34 ,  A61K35/407 ,  A61K35/42 ,  A61K38/43 ,  A61K38/48 ,  A61P9/10

CPC分类号： A61L27/52 ,  A61K35/22 ,  A61K35/30 ,  A61K35/34 ,  A61K35/407 ,  A61K35/42 ,  A61K38/363 ,  A61K38/4833 ,  A61L27/225 ,  A61L27/26 ,  A61L27/3633 ,  A61L27/3683 ,  A61L27/3691 ,  A61L27/3695 ,  A61L27/54 ,  A61L2430/00 ,  A61L2430/20 ,  A61L2430/32 ,  C12N5/0068 ,  C12N2533/50 ,  C12N2533/56 ,  C12N2533/90

摘要： A hybrid gel comprising a particulate decellularized tissue (obtained by pulverizing animal-derived biological tissues that are decellularized (decellularized biological tissues)), fibrinogen and thrombin; a cell culture material comprising the hybrid gel; a method for preparing the hybrid gel; and a kit comprising a particulate decellularized tissue and a biological tissue adhesive are provided. The hybrid gel of the present invention exerts the effect to promote differentiation and gain of function of stem cells and the therapeutic effect to a variety of diseases.