公开(公告)号：EP3269402A1

公开(公告)日：2018-01-17

申请号：EP16761714.1

申请日：2016-03-07

申请人： The Chemo-Sero-Therapeutic Research Institute ,  Adeka Corporation ,  National University Corporation Tokyo Medical and Dental University ,  Sapporo Medical University

发明人： SAGA, Hideki ,  UCHIDA, Takanori ,  TOKOROZAKI, Shoko ,  HIWATARI, Ken-Ichiro ,  OBARA, Haruki ,  KISHIDA, Akio ,  KIMURA, Tsuyoshi ,  NEGISHI, Jun ,  HIGAMI, Tetsuya ,  FUNAMOTO, Seiichi

IPC分类号： A61L31/00

CPC分类号： A61L31/046 ,  A61L24/106 ,  A61L31/005 ,  A61L31/10 ,  A61L2300/424

摘要： An anti-adhesion material comprising decellularized tissues and a biocompatible polymer or fibrin glue; a method for preparing an anti-adhesion material comprising complexing a biocompatible polymer or fibrin glue to decellularized tissues; an anti-adhesion material kit comprising decellularized tissues and a biocompatible polymer or fibrin glue; a substitute biomembrane comprising decellularized tissues and a biocompatible polymer or fibrin glue; a method for preparing a substitute biomembrane comprising complexing a biocompatible polymer or fibrin glue to decellularized tissues; and a substitute biomembrane kit comprising decellularized tissues and a biocompatible polymer or fibrin glue.

摘要翻译： 包含脱细胞组织和生物相容性聚合物或纤维蛋白胶的抗粘连材料; 制备抗粘连材料的方法，所述方法包括将生物相容性聚合物或纤维蛋白胶与脱细胞组织复合; 包含脱细胞组织和生物相容性聚合物或纤维蛋白胶的抗粘连材料试剂盒; 包含去细胞组织和生物相容性聚合物或纤维蛋白胶的替代生物膜; 制备替代生物膜的方法，其包括将生物相容性聚合物或纤维蛋白胶与脱细胞组织复合; 以及包含去细胞组织和生物相容性聚合物或纤维蛋白胶的替代生物膜试剂盒。

公开(公告)号：EP2995326A1

公开(公告)日：2016-03-16

申请号：EP14795291.5

申请日：2014-05-02

申请人： The Chemo-Sero-Therapeutic Research Institute ,  National University Corporation Tokyo Medical and Dental University ,  Sapporo Medical University ,  ADEKA CORPORATION

发明人： MATSUDA, Junichi ,  MIYABASHIRA, Sumika ,  HARANO, Satomi ,  KISHIDA, Akio ,  KIMURA, Tsuyoshi ,  NEGISHI, Jun ,  HIGAMI, Tetsuya ,  FUNAMOTO, Seiichi ,  HIWATARI, Ken-ichiro ,  TASAKI, Akiko

IPC分类号： A61L27/00 ,  A61K9/06 ,  A61K35/12 ,  A61K35/28 ,  A61K35/30 ,  A61K35/34 ,  A61K35/407 ,  A61K35/42 ,  A61K38/43 ,  A61K38/48 ,  A61P9/10

CPC分类号： A61L27/52 ,  A61K35/22 ,  A61K35/30 ,  A61K35/34 ,  A61K35/407 ,  A61K35/42 ,  A61K38/363 ,  A61K38/4833 ,  A61L27/225 ,  A61L27/26 ,  A61L27/3633 ,  A61L27/3683 ,  A61L27/3691 ,  A61L27/3695 ,  A61L27/54 ,  A61L2430/00 ,  A61L2430/20 ,  A61L2430/32 ,  C12N5/0068 ,  C12N2533/50 ,  C12N2533/56 ,  C12N2533/90

摘要： A hybrid gel comprising a particulate decellularized tissue (obtained by pulverizing animal-derived biological tissues that are decellularized (decellularized biological tissues)), fibrinogen and thrombin; a cell culture material comprising the hybrid gel; a method for preparing the hybrid gel; and a kit comprising a particulate decellularized tissue and a biological tissue adhesive are provided. The hybrid gel of the present invention exerts the effect to promote differentiation and gain of function of stem cells and the therapeutic effect to a variety of diseases.

公开(公告)号：EP2995326B1

公开(公告)日：2019-07-24

申请号：EP14795291.5

申请日：2014-05-02

申请人： KM Biologics Co., Ltd. ,  National University Corporation Tokyo Medical and Dental University ,  Sapporo Medical University ,  ADEKA CORPORATION

发明人： MATSUDA, Junichi ,  MIYABASHIRA, Sumika ,  HARANO, Satomi ,  KISHIDA, Akio ,  KIMURA, Tsuyoshi ,  NEGISHI, Jun ,  HIGAMI, Tetsuya ,  FUNAMOTO, Seiichi ,  HIWATARI, Ken-ichiro ,  TASAKI, Akiko

IPC分类号： A61L27/36 ,  A61K47/00 ,  A61K35/00 ,  A61L15/00

公开(公告)号：EP2752192B1

公开(公告)日：2019-06-26

申请号：EP12827099.8

申请日：2012-09-03

申请人： Adeka Corporation

发明人： KISHIDA, Akio ,  FUNAMOTO, Seiichi ,  HASHIMOTO, Yoshihide ,  NEGISHI, Jun ,  KUWA, Souichiro ,  EMA, Takao ,  KOBAYASHI, Kuniharu

IPC分类号： A61L27/00 ,  A61L27/36

公开(公告)号：EP2752192A1

公开(公告)日：2014-07-09

申请号：EP12827099.8

申请日：2012-09-03

申请人： Adeka Corporation

发明人： KISHIDA, Akio ,  FUNAMOTO, Seiichi ,  HASHIMOTO, Yoshihide ,  NEGISHI, Jun ,  KUWA, Souichiro ,  EMA, Takao ,  KOBAYASHI, Kuniharu

IPC分类号： A61K35/12 ,  A61L27/00

CPC分类号： A61K35/36 ,  A61K35/30 ,  A61K35/34 ,  A61L27/3604 ,  A61L27/362 ,  A61L27/3625 ,  A61L27/3691 ,  A61L2430/40

摘要： Provided are: a method for preparing a decellularized tissue product in which decellularized tissue can be filled with liquid while changes in the structure of support tissue constituting the decellularized tissue are inhibited; and a graft provided with a decellularized tissue product. The method for preparing a decellularized tissue product includes a reduced-pressure step for bringing an animal-derived decellularized tissue material and a liquid into contact under reduced-pressure conditions, and/or a pressurized step for bringing same into contact under pressurized conditions. The graft is provided with a decellularized tissue product prepared by the method of preparation.

摘要翻译： 本发明提供：用于制备其中脱细胞化组织可以填充有液体，同时在构成所述脱细胞化组织支持的组织的结构的变化被抑制一个脱细胞化组织产品的方法; 和接枝设置有脱细胞化组织的产品。 用于制备脱细胞化组织产品的方法，包括：用于使来自动物的脱细胞化组织材料的减压工序和减压条件下是液体接触，和/或用于使同进在加压条件下接触的步骤加压。 接枝设有由制备方法制备的脱细胞化组织的产品。