公开(公告)号：EP0722733A4

公开(公告)日：1998-05-20

申请号：EP94917801

申请日：1994-06-10

申请人： TEIJIN LTD

发明人： SEKI JIRO ,  KATO YASUKO ,  NISHIO MIE ,  WATANABE KUNIHITO

IPC分类号： A61K31/557 ,  A61K31/5575

CPC分类号： A61K31/557 ,  A61K31/5575

摘要： A blood vessel thickening inhibitor and a smooth muscle fiber migration inhibitor each containing as the active ingredient a 7-thiaprostaglandin E1 compound represented by general formula (I) and useful for inhibiting blood vessel thickening caused mainly by the migration or proliferation of vascular smooth muscle fibers after angioplasty, arterial bypass operation, and so forth, wherein R represents hydrogen, etc.; R represents hydrogen, etc.; R represents linear branched alkyl, etc.; n represents 0 or 1; and symbol * represents an asymmetric carbon atom.

公开(公告)号：EP0763523A4

公开(公告)日：1997-12-10

申请号：EP95919663

申请日：1995-05-30

申请人： TEIJIN LTD

发明人： TAKENOUCHI KAZUYA ,  TAKAHASHI KATSUSHI ,  HASEGAWA MASAICHI ,  TAKEUCHI TAKAHIRO ,  KOMORIYA KEIJI

IPC分类号： C07C233/11 ,  C07C233/22 ,  C07C233/55 ,  C07C233/65 ,  C07C233/75 ,  C07C233/81 ,  C07C235/38 ,  C07C235/42 ,  C07C235/56 ,  C07C235/64 ,  C07C235/84 ,  C07C237/20 ,  C07C237/44 ,  C07C255/60 ,  C07C311/46 ,  C07C323/29 ,  C07C323/60 ,  C07C323/62 ,  C07D257/04 ,  A61K31/165 ,  A61K31/19 ,  A61K31/245 ,  C07C233/87 ,  C07C317/44

CPC分类号： C07D257/04 ,  C07C233/11 ,  C07C233/22 ,  C07C233/55 ,  C07C233/65 ,  C07C233/75 ,  C07C233/81 ,  C07C235/38 ,  C07C235/42 ,  C07C235/56 ,  C07C235/64 ,  C07C235/84 ,  C07C237/20 ,  C07C237/44 ,  C07C255/60 ,  C07C311/46 ,  C07C323/29 ,  C07C323/60 ,  C07C323/62

摘要： A naphthalene derivative represented by general formula (I), a medicinally acceptable salt thereof, or a medicinally acceptable solvate of the derivative or the salt. In said formula (I) A represents hydrogen, hydroxy, alkoxy, etc.; B represents O, S, CO, etc.; C represents CO, CH2CH2CO, etc.; D represents hydrogen, NO2, NH2, etc.; E represents hydrogen, OH, SO2NH2, etc.; and F represents hydrogen, lower alkyl, etc. The compounds have the effect of, e.g., inhibiting IgE antibody production and are useful as, e.g., a preventive and/or a remedy for allergic diseases.

公开(公告)号：EP0726076A4

公开(公告)日：1997-10-29

申请号：EP94931168

申请日：1994-10-27

申请人： CHEMO SERO THERAPEUT RES INST ,  TEIJIN LTD

发明人： MIYATA KAZUMASA ,  AKIMOTO YOSHINORI ,  OGATA YOICHI ,  NAKAGAKI TOMOHIRO

IPC分类号： A61K38/43 ,  A61K38/46 ,  A61K38/48 ,  A61P7/02 ,  C12N9/64 ,  C12N9/96 ,  A61K38/36

CPC分类号： C12N9/6464 ,  A61K38/4866 ,  C12N9/96 ,  C12Y304/21069

摘要： A method for stabilizing protein C or activated protein C and a preparation obtained by said method are provided, said method and preparation being applicable during procedures such as isolation and purification, lyophilization, heating, etc. or when stored. To a salt buffer containing protein C or activated protein C and sodium ion are added at least one amino acids, and further either one or a combination of albumin and a non-ionic surfactant.

公开(公告)号：EP0659728A4

公开(公告)日：1997-08-06

申请号：EP93919623

申请日：1993-09-07

申请人： TEIJIN LTD

发明人： FURUYA MINORU ,  SUGIURA SATOSHI ,  HAZATO ATSUO

IPC分类号： C07C45/67 ,  C07C49/707 ,  C07C49/723 ,  C07C49/743 ,  C07C49/747 ,  C07C49/753 ,  C07C69/007 ,  C07C69/738 ,  C07C69/76 ,  C07C69/96 ,  C07C205/45 ,  C07C225/22 ,  C07C405/00 ,  C07D213/50 ,  C07D277/16 ,  C07D309/12 ,  C07D333/22 ,  C07F7/18 ,  C07H13/04 ,  C07H13/06 ,  C07C59/90 ,  C07C69/16

CPC分类号： C07H13/04 ,  C07C45/673 ,  C07C49/707 ,  C07C49/723 ,  C07C49/743 ,  C07C49/747 ,  C07C49/753 ,  C07C69/007 ,  C07C69/738 ,  C07C69/76 ,  C07C69/96 ,  C07C205/45 ,  C07C225/22 ,  C07C405/00 ,  C07C2601/10 ,  C07C2601/14 ,  C07D213/50 ,  C07D277/16 ,  C07D309/12 ,  C07D333/22 ,  C07F7/1852 ,  C07F7/1856 ,  C07H13/06

摘要： An optically active compound represented by general formula (I), a mixture thereof, and a carcinostatic and osteogenesis promoter each containing the same as the active ingredient, wherein Y represents hydrogen or halogen; A represents hydroxy, C2-C7 acyloxy, C2-C5 alkoxycarbonyloxy or C1-C7 sulfonyloxy and B represents hydrogen, or alternatively A and B are combined together to represent a bond; R2 represents a C¿4?-C10 alicyclic hydrocarbon, C6-C10 aromatic hydrocarbon or C1-C9 heterocyclic hydrocarbon group each of which may be substituted; R?3¿ represents hydrogen or a C¿1?-C10 aliphatic hydrocarbon, C4-C10 alicyclic hydrocarbon or C6-C10 aromatic hydrocarbon group each of which may be substituted; R?4¿ represents hydrogen, C¿1?-C4 alkyl, C2-C7 acyl, C2-C5 alkoxycarbonyl, tri(C1-C7 hydrocarbyl)silyl or a group which forms an acetal bond together with the oxygen atom to which the R?4¿ is bonded; and R5 represents hydrogen or a C¿1?-C10 aliphatic hydrocarbon or C4-C10 alicyclic hydrocarbon group each of which may be substituted.

摘要翻译： 由通式（I）表示的光学活性化合物及其混合物，以及各自含有与活性成分相同的制癌和成骨促进剂，其中Y表示氢或卤素; A表示羟基，C 2 -C 7酰氧基，C 2 -C 5烷氧基羰基氧基或C 1 -C 7磺酰氧基，B表示氢，或者A和B组合在一起表示键; R 2表示可以被取代的C 4 -C 10脂环族烃，C 6〜C 10芳香族烃或C 1〜C 9杂环烃基; R 3表示氢或可以被取代的C 1 -C 10脂族烃，C 4 -C 10脂环族烃或C 6〜C 10芳族烃基; R 4表示氢，C 1 -C 4烷基，C 2 -C 7酰基，C 2 -C 5烷氧基羰基，三（C 1 -C 7烃基）甲硅烷基或与R 4基团的氧原子一起形成缩醛键的基团， 结合; R 5代表氢或可以被取代的C 1 -C 10脂族烃或C 4 -C 10脂环族烃基。

公开(公告)号：EP0745713A4

公开(公告)日：1997-06-25

申请号：EP95938031

申请日：1995-11-17

申请人： TEIJIN LTD

发明人： YOSHIDA NORIO ,  SHIMADA KOJIRO ,  SHIBATA FUMIO ,  TACHIKA SEIJI

IPC分类号： D03D15/00 ,  D03D15/06 ,  D06C27/00 ,  D02G3/02 ,  D06C7/00 ,  D06C11/00 ,  D06C19/00

CPC分类号： D02G3/406 ,  D02G3/36 ,  D03D11/00 ,  D03D15/00 ,  D03D15/0027 ,  D03D15/0061 ,  D03D15/0083 ,  D03D15/06 ,  D06C27/00 ,  D10B2331/04 ,  D10B2401/062 ,  Y10T428/2395 ,  Y10T428/2481 ,  Y10T428/24901 ,  Y10T442/2008 ,  Y10T442/3146 ,  Y10T442/3154 ,  Y10T442/3163

摘要： A nubuck type woven fabric comprising a two-layered structural yarn wherein ultra-fine polyester multi-filaments are primarily disposed at a sheath portion and polyester multi-filaments having a large single fiber size are primarily disposed at a core portion,and having an apparent specific gravity of 0.35 to 0.7 and a shearing rigidity of 0.5 to 1.0 gf/cm deg. This woven fabric is produced by dissolving and removing an easily soluble component from a woven fabric having a two-layered structural yarn comprising a split type or sea-island type composite fiber multi-filaments consisting of the easily soluble component and an ultra-fine polyester multi-filament forming component, and highly shrinkable polyester multi-filaments, without substantially shrinking the woven fabric, and then shrinking the woven fabric in an open width state.

公开(公告)号：EP0726311A4

公开(公告)日：1997-06-11

申请号：EP94931171

申请日：1994-10-27

申请人： JURIDICAL FOUNCATION THE CHEMO ,  TEIJIN LTD

发明人： OGATA YOICHI ,  NOUCHI TOSHINOBU ,  NAKAHIRA SHINJI

IPC分类号： A61K38/46 ,  A61P7/02 ,  C07K1/18 ,  C07K1/22 ,  C07K14/755 ,  C12N9/64

CPC分类号： C12N9/6464 ,  C12Y304/21069 ,  Y10S530/83 ,  Y10S530/856

摘要： A human activated protein C preparation having a high specific activity and being substantially free from thrombin or equivalent protease and/or nonactivated protein C. The preparation has a specific activity higher than 3500 V/mg in the test wherein the activated partial thromboplastin time (APTT) serves as an index. The production process is based on the method of purifying a human activated protein C by activating protein C with thrombin, etc., bringing a solution containing the activated protein C into contact with a cation exchanger to adsorb the thrombin and the activated protein C, and eluting only the activated protein C.

公开(公告)号：EP0685509A4

公开(公告)日：1997-05-02

申请号：EP94902100

申请日：1993-12-10

申请人： TEIJIN LTD

发明人： MINAMIHIRA YUKIHIKO ,  IZUMI YUZURU ,  KUBO KOUJI ,  MURAKAMI YOJI ,  ONO TADASHI

IPC分类号： B32B15/08 ,  C08J5/18

CPC分类号： B32B15/09 ,  B32B1/02 ,  B32B15/08 ,  B32B15/18 ,  B32B2307/412 ,  B32B2307/518 ,  B32B2307/704 ,  B32B2307/718 ,  B32B2309/105 ,  B32B2367/00 ,  B32B2439/66 ,  C08J5/18 ,  C08J2367/02

摘要： A transparent polyester film for use in the lamination coating of metallic cans, substantially formed from a polyester composition prepared by homogeneously mixing: (A) 70-40 wt.% of a polyethylene terephthalate based on repeating ethylene terephthalate units and having a melting point of 250-262 °C, and (B) 30-60 wt.% of a polybutylene terephthalate based on repeating butylene therephthalate units and having a melting point of 215-225 °C. The film is characterized by: (i) having a crystallization temperature of 65-120 °C, (ii) having a secondary transition point of 40 °C or above, (iii) having a plane orientation coefficient of 2.12 to 0.19 and (iv) being substantially free from the occurrence of white spots even when treated with steam at 130 °C for 30 minutes after being laminated with a metallic sheet. This film does not form any white spot after retorting when used for the lamination coating of metallic cans.

公开(公告)号：EP0572679A4

公开(公告)日：1995-08-16

申请号：EP93900393

申请日：1992-12-18

申请人： TEIJIN LTD

发明人： MAKINO OSAMU ,  MATSUI MICHIKAGE

IPC分类号： D01F6/60

CPC分类号： D01F6/605 ,  D01D5/253 ,  Y10T428/29 ,  Y10T428/2913 ,  Y10T428/2969 ,  Y10T428/2973

公开(公告)号：EP0623608A4

公开(公告)日：1995-04-19

申请号：EP93902518

申请日：1993-01-22

申请人： TEIJIN LTD

发明人： SHIOTA TATSUKI ,  TAKEYASU TAKUMI ,  MOCHIZUKI TSUTOMU ,  KATAOKA KENICHIRO ,  TANABE HIROFUMI ,  OTA MIKIO ,  KANOH MASATOSHI ,  YAMAGUCHI HISAO

IPC分类号： A61K31/35 ,  C07D311/22 ,  C07D311/58 ,  C07D311/96

CPC分类号： C07D311/22 ,  C07D311/58 ,  C07D311/96

摘要： A benzopyran derivative represented by general formula (1), an acid adduct thereof, a process for producing the same, and a pharmaceutical preparation containing the same as the active ingredient. In the said formula, X represents alkyl, alkoxy, etc.; R1s represent each independently alkyl, alkoxy, etc.; R2 to R7 represent each hydrogen, alkyl, etc.; R8 represents alkyl, aryl, etc.; R9 represents hydrogen, lower alkyl, etc.; m and n represent each an integer of 0 to 3 provided that the sum of m and n represents an integer of 3 or less; and o represents 0 or 1.

摘要翻译： 由通式（1）表示的苯并吡喃衍生物，其酸加合物，其制备方法和含有该苯并吡喃衍生物的活性成分的药物制剂。 在所述式中，X表示烷基，烷氧基等; R 1表示各自独立的烷基，烷氧基等; R 2〜R 7各自表示氢，烷基等; R 8表示烷基，芳基等; R 9表示氢，低级烷基等; m和n分别表示0〜3的整数，m和n的和表示3以下的整数。 和o表示0或1.

公开(公告)号：EP0611683A4

公开(公告)日：1995-01-18

申请号：EP93919663

申请日：1993-09-14

申请人： TEIJIN LTD

发明人： NISHIMURA KUNIO ,  NAKAGAWA HIDEO ,  KUMAKAWA SHIRO

IPC分类号： B60R21/16 ,  B60R21/233

CPC分类号： B60R21/233 ,  B60R21/2338 ,  B60R2021/23382

摘要： An air bag with reinforcing belts having high burst strength and superior safety comprising a circular top cloth (1), a circular bottom cloth (2) sewn to said circular top cloth and having an inflator mounting circular hole at its central portion, top and bottom reinforcing cloth pieces (5), (6) sewn to the central portions of said top and bottom cloth, respectively, and a plurality of reinforcing belts (7) disposed on the internal sides of said top and bottom cloths, wherein one ends of said reinforcing belts are connected to a top belt catcher (17) sewn to said top reinforcing cloth piece or said top cloth, wherein the other ends of said renforced belts is connected to a bottom belt catcher (18) sewn to said bottom reinforcing cloth piece or said bottom cloth, and wherein said top cloth and said bottom cloth are sewn, respectively , to their corresponding reinforcing cloth and, if required, to their corresponding belt catcher along a concentric closing sewing line and satisfies the following relation (I): 0.45 « Ζ/L « 2.95 [where Ζ is the shortest straight distance between two intersection points at which a line passing through the center of said circular top or bottom cloth intersects the outermost circumference of said sewing line, and L is a straight distance from an intersection point between the longitudinal central axis of said reinforcing belt and the outermost circumferential sewing line of said top reinforcing cloth piece to an intersection point between the longitudinal central axis of said reinforced belt and the outermost circumferential sewing line of said bottom reinforcing cloth piece.]

摘要翻译： 一种具有高爆破强度和优异安全性的加强带的气囊，包括圆形顶布（1），环形底布（2），缝合到所述圆形顶布上，并且在其中心部分具有充气机安装圆形孔，顶部和底部 分别缝合在所述顶布和底布的中央部分的加强布片（5），（6）和设置在所述顶布和底布内侧上的多个加强带（7），其中所述 加强带连接到缝合到所述顶部增强布件或所述顶布上的顶部皮带抓取器（17），其中所述增强皮带的另一端连接到缝合到所述底部加强布件的底部皮带抓取器（18），或 所述底布，并且其中所述顶布和所述底布分别缝合到其相应的增强布，并且如果需要，沿着同心闭合缝合线缝合到其相应的皮带抓持器，并且满足所述底布 （I）：0.45