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1011 条记录 (耗时 0.034 秒)

    A system, method and apparatus for use in blood testing through luminescence
    93.
    发明公开
    A system, method and apparatus for use in blood testing through luminescence 审中-公开
    系统，Verfahren和Vorrichtung zur Verwendung beim Bluttest durch Lumineszenz

    公开(公告)号：EP1830175A2

    公开(公告)日：2007-09-05

    申请号：EP07004201.5

    申请日：2007-03-01

    申请人： Gemoscan International Inc.

    发明人： Ostrovsky, Aleksandr ,  Leibovski, Mikhail

    IPC分类号： G01N21/76 ,  G01N35/02 ,  G01N35/10 ,  G01N33/49

    CPC分类号： G01N21/76 ,  G01N35/025 ,  G01N2035/0491 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/114998 ,  Y10T436/25 ,  Y10T436/25375 ,  Y10T436/2575

    摘要： The present invention seeks to provide an express-control system for analysing the compatibility of blood with other substances. The present invention relates to a system, method and apparatus for use in blood testing and more specifically, food intolerance testing through analysis of blood using luminescence. The present invention utilises a blood testing system and apparatus, which includes a displacement assembly (4), a blood divider assembly (6), a reagent divider assembly (7), an electro-optical multiplier assembly (8) and a central controller (10). A sample of blood is added to a corresponding one of a plurality of canisters (20) containing a test substance. Thereafter a luminescent reagent is added and the plurality of canisters are moved in the blood testing apparatus until the canisters begin to luminese. The amount of luminescence is measured and analysed an indicator of compatibility of the blood with the test substance and more specifically as an indicator of the presence and activity of neutrophil in the blood and more specifically the granulacy of the blood.

    摘要翻译： 本发明寻求提供一种用于分析血液与其他物质的相容性的快速控制系统。 本发明涉及一种用于血液检测的系统，方法和装置，更具体地，涉及使用发光分析血液的食物不耐受性测试。 本发明使用血液检查系统和装置，其包括位移组件（4），分血器组件（6），试剂分配器组件（7），电光学乘法器组件（8）和中央控制器 10）。 将血液样品加入到含有测试物质的多个罐（20）中的相应的一个。 此后，加入发光试剂，并且将多个罐在血液检测装置中移动，直到罐开始发光。 测量发光量并分析血液与测试物质的相容性的指标，更具体地说，作为血液中嗜中性粒细胞的存在和活性的指标，更具体地说是血液的颗粒物。

    METHOD AND APPARATUS FOR INCREASING THE DYNAMIC RANGE AND ACCURACY OF BINDING ASSAYS
    94.
    发明公开
    METHOD AND APPARATUS FOR INCREASING THE DYNAMIC RANGE AND ACCURACY OF BINDING ASSAYS 审中-公开
    方法和设备用于增加结合试验的动态范围和精度

    公开(公告)号：EP1481234A4

    公开(公告)日：2007-08-08

    申请号：EP02769030

    申请日：2002-10-11

    申请人： BECKMAN COULTER INC

    发明人： KEYS DANIEL A ,  REDDY PARAMESWARA M

    IPC分类号： G01N21/64 ,  G01N21/76 ,  G01N21/00 ,  G01N33/53

    CPC分类号： G01N21/76 ,  G01N21/6428

    摘要： This invention relates to methods for increasing the dynamic range and accuracy of assays in which the presence, absence, activity or concentration of a target analyte is assayed by the emission or quenching of a light signal, or by a change (i.e., an evolution or loss) of a light signal in two or more time intervals. In preferred embodiments multiple digitized images are captured at varying times, and the images analyzed to identify captured images within the dynamic range of the assay. The invention further relates to apparati capable of implementing such methods.

    LUCIFERASE LUMINESCENCE METHOD AND LUMINESCENT REAGENT
    96.
    发明公开
    LUCIFERASE LUMINESCENCE METHOD AND LUMINESCENT REAGENT 审中-公开
    LUCIFERASE-LUMINESZENZVERFAHREN UND LUMINESZENZREAGENS

    公开(公告)号：EP1793002A1

    公开(公告)日：2007-06-06

    申请号：EP05768780.8

    申请日：2005-08-02

    申请人： Toyo B-Net Co., Ltd

    发明人： RYUFUKU, Masayuki, c/o TOYO B-NET CO., LTD. ,  NOMURA, Ryosuke, c/o TOYO B-NET CO., LTD. ,  KURITA, Akihiro, c/o TOYO B-NET CO., LTD.

    IPC分类号： C12Q1/66 ,  G01N21/78

    CPC分类号： G01N21/76 ,  C12Q1/66 ,  G01N2333/90241

    摘要： The present invention provides a stabilized luminescence system by extending the half-life of Coleoptera luciferin/luciferase luminescent reactions. A luminescence method for luciferin/luciferase system, comprising reacting a luciferin with a Coleoptera luciferase in the presence of pyrophosphoric acid and/or a pyrophosphate to thereby generate a luminescence whose half-life is 5 minutes or more is provided. A method of using the same, luminescent reagents and luminescent reagent kits are also provided.

    摘要翻译： 本发明通过延长鞘翅目荧光素/荧光素酶发光反应的半衰期来提供稳定的发光系统。 荧光素/荧光素酶系统的发光方法，包括在焦磷酸和/或焦磷酸盐的存在下使荧光素与鞘翅目荧光素酶反应，从而产生半衰期为5分钟以上的发光。 还提供了使用它们的方法，发光试剂和发光试剂盒。

    PHOTONIC SIGNAL REPORTING OF ELECTROCHEMICAL EVENTS
    98.
    发明公开
    PHOTONIC SIGNAL REPORTING OF ELECTROCHEMICAL EVENTS 审中-公开
    PHOTON信号消息电化学活动

    公开(公告)号：EP1552011A4

    公开(公告)日：2006-11-08

    申请号：EP03765936

    申请日：2003-07-22

    申请人： TEXAS A & M UNIV SYS

    发明人： CROOKS RICHARD M ,  ZHAN WEI ,  ALVAREZ JULIO

    IPC分类号： C12Q1/00 ,  G01N21/76 ,  G01N33/543 ,  C12Q1/68 ,  G01N15/06 ,  G01N21/62

    CPC分类号： C12Q1/001 ,  G01N21/76 ,  G01N33/5438

    摘要： According to one embodiment of the invention, a method for detecting the presence or amount of an analyte includes associating a first electrolyte solution containing the analyte with a first region of a bipolar electrode, associating a second electrolyte solution containing an electrochemiluminescent system with a second region of the bipolar electrode, ionically isolating the first electrolyte solution from the second electrolyte solution, causing a potential difference between the first and second electrolyte solutions, and detecting light emitted from the electrochemiluminescent system, thereby indicating the presence or amount of the analyte at the first region of the bipolar electrode.

    Imaging fluorescence signals using telecentric optics on the excitation and the imaging side
    100.
    发明公开
    Imaging fluorescence signals using telecentric optics on the excitation and the imaging side 有权
    Fluoreszenzabbildung mittels telezentrischer Optiken auf Anregungs- und Abbildungsseite

    公开(公告)号：EP1681558A1

    公开(公告)日：2006-07-19

    申请号：EP06000788.7

    申请日：2006-01-14

    申请人： Roche Diagnostics GmbH ,  F.HOFFMANN-LA ROCHE AG

    发明人： Gutekunst, Martin ,  Guse, Frank ,  Heckmann, Hans-Georg ,  Hessling, Martin ,  Koenig, Joachim

    IPC分类号： G01N21/64

    CPC分类号： G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/76 ,  G01N2021/6478 ,  G01N2201/0631

    摘要： The present invention relates to the field of DNA analysis. In particular, the present invention is directed to a device for the parallel imaging of fluorescence intensities at a plurality of sites as a measure for DNA hybridization. More particular, the present invention is directed to a device to image multiplex real time PCR or to read out DNA microarrays.
    According to a preferred embodiment the device comprises holding means (1) for holding a planar support (2) with an assembly of multiple individual sites (3); at least one light source (4) for emitting light comprising at least one excitation frequency; a transducer (5) for receiving fluorescence signals from said sites; a field lens (6); an excitation lens arrangement (10), and an imaging lens arrangement (11), wherein said excitation path and said fluorescence imaging light path are telecentric on the object side of said field lens and wherein the angle of indidence of the excitation light with said planar support is larger than 0°.

    摘要翻译： 本发明涉及DNA分析领域。 特别地，本发明涉及用于在多个位点处的荧光强度的平行成像作为DNA杂交的量度的装置。 更具体地，本发明涉及一种用于对多重实时PCR进行成像或读出DNA微阵列的装置。 根据优选实施例，该装置包括用于用多个单独位置（3）的组件保持平面支撑件（2）的保持装置（1）。 用于发射包括至少一个激发频率的光的至少一个光源（4） 用于从所述位置接收荧光信号的换能器（5） 场透镜（6）; 激励透镜装置（10）和成像透镜装置（11），其中所述激发路径和所述荧光成像光路在所述场透镜的物体侧是远心的，并且其中所述激发光与所述平面 支持大于0°。