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公开(公告)号：EP0411907A3
公开(公告)日：1991-07-24
申请号：EP90308424.2
申请日：1990-07-31
Applicant: ORTHO DIAGNOSTIC SYSTEMS INC.
Inventor： Schutt, Ernest G. , Greenwood, David L. , Utberg, Karin
CPC classification number: G01N21/552 , G01J3/0216 , G01J3/0243 , G01J3/0297 , G01N21/21 , G01N21/47 , G01N33/553 , G01N33/585 , Y10S436/807
Abstract: A new immunoassay system is provided for the detection of ligands or ligand binding partners in solution in a heterogeneous format. The invention relies upon the detection of back scattered light from an evanescent wave disturbed by the presence of a colloidal gold label brought to the interface by an immunological reaction. The evanescent wave existing at the interface in turn is the result of a totally internally reflected incident light wave. Placement of the detector at a back angle above the critical angle insures a superior signal-to-noise ratio. Apparatus and methods for scanning, detecting and manipulating light including a scattered total internal reflectance immunoassay system are provided.
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112.发明授权
公开(公告)号：EP2413784B1
公开(公告)日：2024-07-17
申请号：EP10759220.6
申请日：2010-03-23
IPC: A61B5/00
CPC classification number: A61B5/14532 , A61B5/1455 , G01J3/02 , G01J3/0216 , G01J3/10 , G01J3/18 , G01J3/42 , G01J2003/123920130101 , G01N21/359
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公开(公告)号：EP3193701B1
公开(公告)日：2018-09-26
申请号：EP15762934.6
申请日：2015-08-24
Applicant: RSP Systems A/S
Inventor： BANKE, Stefan Ovesen
IPC: A61B5/00 , G01J3/44 , G01N21/65 , A61B5/145 , A61B5/1455
CPC classification number: A61B5/0075 , A61B5/14532 , A61B5/1455 , A61B5/14551 , A61B5/7221 , G01J1/4257 , G01J3/0208 , G01J3/0216 , G01J3/44 , G01N21/65
Abstract: The use of a transdermal Raman spectrum to measure glucose or other substance concentration can give an inaccurate result if the Raman signals originate at a wrong skin depth. To predict whether a spectrum of Raman signals received transdermally in a confocal detector apparatus and having at least one component expected to have an intensity representing the concentration of glucose or another skin component at a point of origin of the Raman signals below the surface of the skin will accurately represent the concentration, peaks in the spectrum at 883/4 cm−1 and 894 cm−1 are measured to determine whether the Raman signals originate primarily within the stratum corneum so that the spectrum will be less likely to represent the concentration accurately or originate primarily below the stratum corneum so that the spectrum will be more likely to represent the concentration accurately.
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公开(公告)号：EP2710341B1
公开(公告)日：2018-05-09
申请号：EP12722708.0
申请日：2012-05-14
Applicant: Schiller, Monika
Inventor： SCHILLER, Carl-Albrecht
CPC classification number: G01J3/10 , G01J3/0216 , G01J3/501 , G01J2003/104
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115.发明公开METHOD AND APPARATUS FOR TRANSDERMAL IN VIVO MEASUREMENT BY RAMAN SPECTROSCOPY 有权通过拉曼光谱法进行体内测量透射的方法和装置
公开(公告)号：EP3193701A1
公开(公告)日：2017-07-26
申请号：EP15762934.6
申请日：2015-08-24
Applicant: RSP Systems A/S
Inventor： BANKE, Stefan Ovesen
IPC: A61B5/00 , G01J3/44 , G01N21/65 , A61B5/145 , A61B5/1455
CPC classification number: A61B5/0075 , A61B5/14532 , A61B5/1455 , A61B5/14551 , A61B5/7221 , G01J1/4257 , G01J3/0208 , G01J3/0216 , G01J3/44 , G01N21/65
Abstract: The use of a transdermal Raman spectrum to measure glucose or other substance concentration can give an inaccurate result if the Raman signals originate at a wrong skin depth. To predict whether a spectrum of Raman signals received transdermally in a confocal detector apparatus and having at least one component expected to have an intensity representing the concentration of glucose or another skin component at a point of origin of the Raman signals below the surface of the skin will accurately represent the concentration, peaks in the spectrum at 883/4 cm−1 and 894 cm−1 are measured to determine whether the Raman signals originate primarily within the stratum corneum so that the spectrum will be less likely to represent the concentration accurately or originate primarily below the stratum corneum so that the spectrum will be more likely to represent the concentration accurately.
Abstract translation: 如果拉曼信号源于错误的趋肤深度，使用透皮拉曼光谱测量葡萄糖或其他物质浓度可能会导致不准确的结果。 为了预测在共焦探测器装置中经皮肤接收的拉曼光谱信号是否具有至少一个预期具有代表葡萄糖浓度的强度或在皮肤表面以下的所述拉曼信号的起源点处的另一皮肤成分 将精确地表示所述浓度，测量883 / 4cm-1和894cm-1处的光谱峰值，以确定拉曼信号是否主要起源于角质层内，使得光谱将不太可能精确地表示所述浓度或主要起源于 低于角质层，使得光谱更可能精确地表示所述浓度。
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Patent Agency Ranking
公开(公告)号：EP3055696A4
公开(公告)日：2017-07-05
申请号：EP14852992
申请日：2014-10-09
Applicant: NAT UNIV SINGAPORE
Inventor： TRAU DIETER WILHELM
CPC classification number: G01N21/0303 , G01J1/0422 , G01J3/0216 , G01J3/0291 , G01N21/8507 , G01N2021/0321 , G01N2021/0346 , G01N2201/0221 , G01N2201/08
Abstract: A disposable photometric measurement tip comprising a polymer tip, the polymer tip having a capillary filling channel, the capillary filing channel having an opening at a distal end of the polymer tip, a wave guide channel acting as an optical input coupling and a wave guide channel acting as an optical output coupling, each of the wave guide channels having an opening at a proximal end of the polymer tip wherein the capillary filling channel, the wave guide channel acting as an optical input coupling and the wave guide channel acting as an optical output coupling are connected to each other.
Abstract translation: 包括聚合物尖端的一次性光度测量尖端，所述聚合物尖端具有毛细填充通道，所述毛细填充通道在所述聚合物尖端的远端处具有开口，用作光学输入耦合的波导通道以及波导通道 其用作光学输出耦合，每个波导通道在聚合物末端的近端处具有开口，其中毛细填充通道，波导通道充当光输入耦合并且波导通道充当光输出 耦合彼此连接。
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公开(公告)号：EP3128301A2
公开(公告)日：2017-02-08
申请号：EP16182550.0
申请日：2016-08-03
Applicant: Viavi Solutions Inc.
Inventor： SMITH, Paula , HRUSKA, Curtis R , CATCHING, Benjamin F , COOMBS, Paul G
CPC classification number: G01J3/0229 , G01J3/0205 , G01J3/0208 , G01J3/0216 , G01J3/0218 , G01J3/0262 , G01J3/12 , G01J3/26 , G01J3/2803 , G01J2003/1213 , G01J2003/1217 , G01J2003/123 , G01J2003/1234 , G01J2003/1239 , G01J2003/1291 , G01J2003/2806 , G01J2003/2813 , G01N21/255 , G01N21/8507 , G02B5/22 , G02B5/3025 , G02B6/4215
Abstract: An optical assembly is disclosed including two laterally variable bandpass optical filters stacked at a fixed distance from each other, so that the upstream filter functions as a spatial filter for the downstream filter. The lateral displacement may cause a suppression of the oblique beam when transmission passbands at impinging locations of the oblique beam onto the upstream and downstream filters do not overlap. A photodetector array may be disposed downstream of the downstream filter. The optical assembly may be coupled via a variety of optical conduits or optical fibers for spectroscopic measurements of a flowing sample.
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公开(公告)号：EP2976605A4
公开(公告)日：2016-11-16
申请号：EP14779143
申请日：2014-03-20
Applicant: VIAVI SOLUTIONS INC
Inventor： O'BRIEN NADA A , HULSE CHARLES A , SIESLER HEINZ W , HSIUNG CHANGMENG
CPC classification number: G01N21/359 , G01J3/0216 , G01J3/26 , G01J3/2803 , G01J2003/1234 , G01J2003/2873 , G01N21/27 , G01N21/3563 , G01N21/55 , G01N33/12 , G01N2201/0221 , G01N2201/061 , G01N2201/12
Abstract: A method and apparatus for field spectroscopic characterization of seafood is disclosed. A portable NIR spectrometer is connected to an analyzer configured for performing a multivariate analysis of reflection spectra to determine qualitatively the true identities or quantitatively the freshness of seafood samples.
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公开(公告)号：EP3055696A1
公开(公告)日：2016-08-17
申请号：EP14852992.8
申请日：2014-10-09
Applicant: National University of Singapore
Inventor： TRAU, Dieter Wilhelm
IPC: G01N33/543 , B01L3/02 , G01N33/53
CPC classification number: G01N21/0303 , G01J1/0422 , G01J3/0216 , G01J3/0291 , G01N21/8507 , G01N2021/0321 , G01N2021/0346 , G01N2201/0221 , G01N2201/08
Abstract: A disposable photometric measurement tip comprising a polymer tip, the polymer tip having a capillary filling channel, the capillary filing channel having an opening at a distal end of the polymer tip, a wave guide channel acting as an optical input coupling and a wave guide channel acting as an optical output coupling, each of the wave guide channels having an opening at a proximal end of the polymer tip wherein the capillary filling channel, the wave guide channel acting as an optical input coupling and the wave guide channel acting as an optical output coupling are connected to each other.
Abstract translation: 一种一次性光度测量尖端，包括聚合物尖端，所述聚合物末端具有毛细管填充通道，所述毛细管填充通道在聚合物尖端的远端具有开口，用作光输入耦合的波导通道和波导通道 作为光输出耦合器，每个波导通道在聚合物末端的近端处具有开口，其中毛细填充通道，作为光输入耦合的波导通道和用作光输出的波导通道 耦合相互连接。
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公开(公告)号：EP2929308A1
公开(公告)日：2015-10-14
申请号：EP13860485.5
申请日：2013-12-05
Applicant: Genepoc Inc. , Université Laval
Inventor： LEMIEUX, Hugo , CHAPDELAINE, Sébastien , BÉLIVEAU-VIEL, David , GRAVEL, Jean-François
CPC classification number: G01N21/6486 , G01J3/021 , G01J3/0213 , G01J3/0216 , G01J3/0218 , G01J3/443 , G01J2003/102 , G01N21/6408 , G01N21/6445 , G01N21/645 , G01N21/763 , G01N2021/6419 , G01N2021/6471 , G01N2021/6484 , G01N2201/061
Abstract: An interrogation device for detecting luminescent light produced by analytes in a sample excited by multiple excitation light beams each having individual spectral contents, comprising a plurality of light sources each generating an excitation light beam; at least one detector for detecting the luminescent light produced by the sample; and an optical assembly defining distinct and fixed excitation light paths for each of the excitation light beams from the light sources to a common excitation site on the sample and defining a shared luminescence light path for the luminescent light from the excitation site on sample to the at least one detector, the excitation light paths and the luminescence light path being on a same side of the sample, the optical assembly including sample-side optics projecting the excitation light towards the sample and collecting luminescent light from the sample.
Abstract translation: 一种询问装置，用于检测样品中分析物产生的荧光，该样品由多个激发光束激发，每个激发光束具有单独的光谱内容，包括多个光源，每个光源产生一个激发光束; 至少一个检测器，用于检测样品产生的发光; 以及光学组件，其为来自光源的每个激发光束定义不同的和固定的激发光路径到样品上的共同激发位点，并且限定用于从样品上的激发位点到激光位置处的发光光的共享发光光路 至少一个探测器，激发光路和发光路径位于样品的同一侧，光学组件包括样品侧光学器件，其将激发光投射到样品并收集来自样品的发光。
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