摘要:
The non-invasive detection of fetal chromosomal aneuploidies is demonstrated. Alleles of fetal RNA-SNPs present in a biological sample (e.g. maternal blood) containing fetal RNA are detected and quantified in order to determine the ratio of the alleles. This ratio is compared to a standard control consisting of euploid fetuses. Deviation of allele ratio indicates the presence of chromosomal aneuploidy.
摘要:
The present invention is directed to a method of treating a sudden onset of at least one neurological deficit in a subject. The sudden onset of neurological symptoms is an indicator of a possible stroke, also termed a cerebrovascular accident. The method comprises administering an effective amount of melatonin to the subject immediately after the sudden onset of at least one neurological deficit, and preferably within three hours of the sudden onset of the at least one neurological deficit. Preferably, the effective amount of melatonin is at least about 200 mg and less than about 1000 mg, although for a small child or infant the effective amount of melatonin may be less than about 200 mg while for a large adult it may be more than about 1000 mg. It is expected that the effective amount of melatonin is no more than about 1500 mg in almost all cases.
摘要:
The prosthesis device can have a pair of articular members adapted to be mounted onto adjoining bones, respectively, to replace a joint. The first and second articular members can have first and second bearing elements, respectively. The bearing elements can be formed to be capable of replacing at least a portion of the bone ends of the adjoining bones, respectively, and providing an articulation close to that of a natural joint. The bearing elements can be fixed to the respective bones through an initial implant fixation achieved by press-fit anchoring immediately after surgery and/or a secondary implant fixation established from bone-ingrowth.
摘要:
An apparatus is for use with a container of liquid that is suspended from an aircraft flying over a ground target area. The container has an outlet through which the liquid is dropped from the container. The apparatus includes a diffuser configured to diffude the liquid exiting the container outlet horizontally outward beyond the container into the air above the groud target area, whereby the liquid is diffused over a correspondingly wide area. The liquid can be fire extinguishing liquid, and the ground target area can be a forest fire.
摘要:
The present invention relates to planar materials having bandgap properties. The materials are formed by depositing conductive fractal patterns (Figs. 1A, 1B) on a non−conducting substrate. The bandgap locations(s) are defined by parameters including the number of fractal levels, and the dimension of the fractal mother element (Specification, page 6). The bandgaps can also be controlled by injecting current into the conducting pattern.
摘要:
An aberration in a fetal genome can be identified by analyzing a sample of fetal and maternal DNA. Classifications of whether an aberration (amplification or deletion) exists in a subchromosomal region are determined using count-based and size-based methods. The count classification and the size classification can be used in combination to determine whether only the fetus or only the mother, or both, have the aberration in the subchromosomal region, thereby avoiding false positives when the mother has the aberration and the fetus does not.