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公开(公告)号:EP3238717B1
公开(公告)日:2019-08-28
申请号:EP15872796.6
申请日:2015-12-14
IPC分类号: A61K9/70 , A61K47/34 , A61K47/14 , A61K47/26 , A61K31/618
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公开(公告)号:EP3483230A1
公开(公告)日:2019-05-15
申请号:EP17837000.3
申请日:2017-08-02
IPC分类号: C09J7/20
摘要: A support film for a tape material, includes a film-shaped support formed of polyurethane; and a barrier layer containing an aromatic isocyanate-based polyurethane and a layered inorganic compound and formed on one surface of the support.
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公开(公告)号:EP3391919A1
公开(公告)日:2018-10-24
申请号:EP16875415.8
申请日:2016-12-01
IPC分类号: A61M5/152
CPC分类号: A61M5/152
摘要: A liquid bag according to one embodiment stores liquid containing an active ingredient to be transdermally administered. This liquid bag includes a bag body configured to store the liquid and feed the liquid toward an injection needle. The bag body includes a tubular portion. At least part of the tubular portion is bent with respect to the axial direction of the tubular portion with the liquid being stored in the tubular portion.
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公开(公告)号:EP2441437B1
公开(公告)日:2018-08-08
申请号:EP10786220.3
申请日:2010-06-10
发明人: TERAHARA Takaaki , TOKUMOTO Seiji
CPC分类号: A61K9/0021 , A61K47/34 , A61M37/0015 , A61M2037/0023 , Y02A50/471
摘要: A coating agent has been applied to microneedles having a biodegradable resin, and a relation between its strength and performance has been clarified. As a result thereof, it has been found that the application of the coating agent to microneedles of a biodegradable resin having a predetermined strength or more, that is, a predetermined weight average molecular weight, allows the microneedles to have excellent performance. Further, it has been found that in regard to the coating agent, a predetermined type and amount thereof are also useful to demonstrate the performance. In view of this, when a microneedle device 1 is arranged so that at least a part of a microneedle array 2 provided with microneedles 3 made from polylactic acid having a weight average molecular weight of 40,000 or more is coated with a carrier containing physiologically active ingredients, it is possible to attain excellent migration characteristics of the physiologically active ingredients to a living body.
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公开(公告)号:EP3213764A4
公开(公告)日:2018-06-20
申请号:EP15855242
申请日:2015-10-19
发明人: NISHIMURA SHINPEI , TOKUMOTO SEIJI , ITO TAKESHI , ASADA HAJIME
CPC分类号: A61K9/0021 , A61K9/00 , A61K38/24 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/18 , A61K47/183 , A61M37/0015 , A61M2037/0023 , A61M2037/0053
摘要: The present invention provides a microneedles device comprising: a substrate; a microneedle disposed on the substrate; and a coating layer formed on the microneedle; in which the coating layer comprises a recombinant follicle-stimulating hormone, arginine, and glycerin, in the coating layer, the mass of arginine is 0.07 to 0.75-fold of the mass of the recombinant follicle-stimulating hormone and the mass of glycerin is 0.1 to 2.75-fold of the mass of the recombinant follicle-stimulating hormone.
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公开(公告)号:EP3207923A4
公开(公告)日:2018-06-13
申请号:EP15851347
申请日:2015-10-13
IPC分类号: A61K9/70 , A61K31/485 , A61K47/10 , A61P25/04
CPC分类号: A61K9/7053 , A61K9/7061 , A61K31/00 , A61K31/485 , A61K47/06 , A61K47/10 , C08F226/02 , C08F226/10 , C08K5/092 , C09J7/02
摘要: A patch including: a support; and an adhesive layer disposed on at least one surface of the support, in which the adhesive layer includes: at least one selected from the group consisting of butorphanol and pharmaceutically acceptable salts thereof; a higher aliphatic alcohol; and a non-cross-linking polyvinylpyrrolidone that does not contain vinyl acetate as a constituent monomer thereof.
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公开(公告)号:EP3192556A4
公开(公告)日:2018-05-09
申请号:EP15839413
申请日:2015-09-10
发明人: NISHIMURA SHINPEI , TOKUMOTO SEIJI
CPC分类号: A61M37/0015 , A61K9/0021 , A61K47/183 , A61L31/08 , A61L31/16 , A61L2300/252 , A61M37/00 , A61M2037/0023 , A61M2037/0046 , A61M2037/0053
摘要: The present invention provides a microneedle device comprising: a substrate; a microneedle disposed on the substrate; and a coating layer formed on the microneedle; wherein the coating layer comprises a physiologically active substance, arginine, and glycerin.
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公开(公告)号:EP3210974A4
公开(公告)日:2018-04-11
申请号:EP15852038
申请日:2015-10-21
发明人: SONOBE ATSUSHI , YASUKOCHI TAKASHI , TAKADA YASUNORI , ATARASHI KENJI , SUZUKI MOTOHIRO , YOKOTA SHINICHI
IPC分类号: C07D213/75 , A61K31/44 , A61P11/00 , A61P43/00
CPC分类号: C07D213/75 , A61K31/44
摘要: The present invention provides a compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: wherein R is a hydrogen atom, a C 1-6 alkyl group optionally substituted with one or more hydroxyl groups, a C 1-6 alkoxy group, or a cyano group.
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公开(公告)号:EP2255802B1
公开(公告)日:2018-01-17
申请号:EP09715019.7
申请日:2009-02-09
发明人: MICHINAKA, Yasunari , ANSAI, Yuka
IPC分类号: A61K31/4045 , A61K9/70 , A61K47/02 , A61K47/04 , A61K47/12 , A61K47/22 , A61K47/32 , A61K47/34 , A61K47/36 , A61P25/16
CPC分类号: A61K31/4045 , A61K9/7053 , A61K9/7076
摘要: A patch 1 comprising a backing layer 2 and a pressure-sensitive adhesive layer 3 formed on the backing layer 2, wherein the pressure-sensitive adhesive layer 3 contains (i) ropinirole and a metal salt produced by the reaction of a ropinirole acid adduct and a metal ion containing desalting agent in an equivalent mole or less to the acid adduct and (ii) an adhesive base free of a hydroxyl group and a carboxy group.
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公开(公告)号:EP3266451A1
公开(公告)日:2018-01-10
申请号:EP16758781.5
申请日:2016-02-22
发明人: FUJIWARA, Yoko , YASUKOCHI, Takashi , TAKAGI, Yuka
摘要: A patch includes an adhesive layer and a release liner laminated on at least one surface of a backing. The adhesive layer comprises, as an adhesive base agent, at least one selected from the group consisting of acrylate-based adhesives and rubber-based adhesives, and the adhesive layer comprises 0.3 to 5% by mass of a nonfunctional silicone oil having a kinematic viscosity of 10 to 350 cSt at 25°C.
摘要翻译: 贴片包括层压在背衬的至少一个表面上的粘合剂层和剥离衬垫。 所述粘合剂层包含选自由丙烯酸酯类粘合剂和橡胶类粘合剂组成的组中的至少一种作为粘合剂基剂,并且所述粘合剂层包含0.3至5质量%的具有运动粘度 在25℃下为10至350cSt。
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