公开(公告)号：EP0459241A1

公开(公告)日：1991-12-04

申请号：EP91107978.8

申请日：1991-05-16

申请人： WATERS INVESTMENTS LIMITED

发明人： Fuchs, Martin ,  Merion, Michael

IPC分类号： G01N27/447

CPC分类号： G01N27/44717 ,  G01N27/44743 ,  G01N30/6052 ,  G01N30/6004

摘要： An apparatus is provided for concentrating a solute sample which can be subsequently released for analysis by capillary electrophoresis. The apparatus comprises a tube containing a short length of packed particles or gel (18) adapted to retain sample solutes which particles are retained in the tube by tube constrictions (14,20) or porous plugs (28,30). The tube includes an inlet (24) for introducing a sample into the tube and an outlet (16) for introducing the retained sample into a capillary electrophoresis tube (12).

摘要翻译： 用于毛细管电泳分析。 该装置包括一个包含短长度的填充颗粒或凝胶（18）的管，适于保留样品溶质，颗粒通过管收缩（14,20）或多孔塞（28,30）保留在管中。 管包括用于将样品引入管的入口（24）和用于将保留的样品引入毛细管电泳管（12）的出口（16）。

公开(公告)号：EP0268946A3

公开(公告)日：1990-03-14

申请号：EP87116713.6

申请日：1987-11-12

申请人： DIAGEN Institut für molekularbiologische Diagnostik GmbH

发明人： Henco, Karsten, Dr. ,  Stichel, Arndt ,  Colpan, Metin, Dr.

IPC分类号： C07H1/08 ,  C12N15/00 ,  C12P19/34 ,  C12N15/10 ,  B01J41/06

CPC分类号： G01N30/6052 ,  C12N15/101 ,  G01N30/6065 ,  G01N30/6091 ,  G01N2030/8813 ,  G01N2030/8827 ,  G01N2030/8831 ,  G01N2030/885

摘要： Long-chain nucleic acids are separated from other substances from solutions containing nucleic acids and other materials, and more particularly nucleic acid/protein mixtures from biotechnical preparations from bacteria, viruses, animal and vegetable tissues and cells as well as body liquids, more particularly cell ingredients and/or degradation products thereof as well as components of body liquids which components are not long-chain nucleic acids, by that the long-chain nucleic acids in the nucleic acid-containing solutions, or after disintegration under mild conditions of the tissue cells and/or cells from body liquids are fixed on a porous matrix, whereas the substances to be separated therefrom are washed out from the matrix, and the fixed nucleic acids, if desired, are subsequently removed from the matrix. A device for carrying out the method preferably consists of a cartridge (1) containing the porous matrix (11) and having at least one inlet opening (3) and at least one outlet opening (4).

公开(公告)号：EP0211206B1

公开(公告)日：1989-05-31

申请号：EP86108506.6

申请日：1986-06-21

申请人： PPG INDUSTRIES, INC.

发明人： Beaver, Richard Paul

IPC分类号： C03B37/14 ,  G01N30/56

CPC分类号： B01J20/28023 ,  B01J20/28014 ,  B01J20/281 ,  B01J2220/54 ,  C03B37/14 ,  G01N30/56 ,  G01N30/60 ,  G01N30/6043 ,  G01N30/6052 ,  Y10T29/49801 ,  Y10T29/49838 ,  Y10T29/49934 ,  Y10T29/53996 ,  G01N30/466

公开(公告)号：EP0042683A1

公开(公告)日：1981-12-30

申请号：EP81302486.6

申请日：1981-06-04

申请人： NATIONAL RESEARCH DEVELOPMENT CORPORATION

发明人： Thompson, John Michael ,  Sithamparanadarajah, Rajadurai ,  Stephen, William Irvine

IPC分类号： G01N1/22 ,  G01N30/00

CPC分类号： G01N1/2214 ,  G01N1/405 ,  G01N30/08 ,  G01N30/603 ,  G01N30/6052 ,  G01N30/6091 ,  G01N2001/2826 ,  G01N2030/0095

摘要： An adsorptive trap for monitoring gases and/or vapours comprises a tube (1, 10, 11) (e.g. length about 4-8 cm, internal diameter about 3-5 mm) packed with one or more suitable adsorbents (3,12,18,19) in appropriate amount (e.g. about 0.5 g), each adsorbent being held packed in place between a pair of rigidly fixed porous discs (4,13,20) e.g. porous sintered powder or metal gauze or mesh discs. It has been found that these adsorptive traps provide improved accuracy and precision of measurement as compared with prior art traps in which the adsorbent is relatively loosely packed and retained in the tube. A preferred method of fabricating the traps makes use of thermal contraction and expansion by allowing a previously cooled, contracted, oversize disc to be loosely fitted within the tube and expand on warming to ambient temperature and thereby become rigidly fixed in place.

摘要翻译： 用于监测气体和/或蒸气的吸附阱包括装有一种或多种合适吸附剂的管（1,10,11）（例如长度约4-8厘米，内径约3-5毫米）（3,12,18 ，19）适当量（例如约0.5g），每个吸附剂保持包装在一对刚性固定的多孔盘（4,13,20）之间的适当位置，例如 多孔烧结粉末或金属丝网或网状盘。 已经发现，与其中吸附剂相对松散地包装并保留在管中的现有技术的捕集器相比，这些吸附阱具有提高的测量精度和精度。 制造捕集器的优选方法通过允许先前冷却的收缩的超大型盘松散地装配在管内并在升温至环境温度后膨胀并由此刚性地固定就位而利用热收缩和膨胀。

公开(公告)号：EP0038826A1

公开(公告)日：1981-11-04

申请号：EP80902082.0

申请日：1980-09-22

申请人： GRAAS, Joseph E.

发明人： GRAAS, Joseph E.

IPC分类号： B01D15 ,  G01N30 ,  G01N33

CPC分类号： G01N30/6052 ,  G01N30/02 ,  G01N33/66 ,  G01N33/723 ,  G01N33/726 ,  G01N2030/381 ,  B01D15/361

摘要： Une combinaison d'une micro-colonne (12) ayant une garniture (16) d'un materiau approprie absorbant et un tube de centrifugation (42). Un volume predetermine d'un eluant capable d'effectuer selectivement l'elution d'une substance desiree au travers de la micro-colonne (12) est contenu au-dessus de la garniture (16) de materiau absorbant. La micro-colonne (12) et le tube de centrifugation (42) sont dimensionnes de telle maniere que, par centrifugation du volume predetermine de l'eluant au travers de la micro-colonne, un niveau (46) de l'eluant restant dans la micro colonne (12) et un niveau (44) de l'eluant dans le tube centrifugation (42) coincident sensiblement avec ou au-dessus de la surface superieure (18) de la garniture (16) de materiau absorbant. En consequence, la centrifugation de l'ensemble de la micro-colonne (12) et du tube de centrifugation (42) provoque le passage d'un volume predetermine d'eluant au travers de la micro-colonne (12). La determination ou analyse de la substance desiree eluee de maniere selective peut etre effectuee par des procedes de spectrophotometrie. Le dispositif et le procede decrits se pretent particulierement a la determination ou analyse d'une concentration relative d'especes d'hemoglobines glycosylees presentes dans les cellules rouges du sang d'une personne.

公开(公告)号：EP1700113B1

公开(公告)日：2018-04-25

申请号：EP04814724.3

申请日：2004-12-08

申请人： Honeywell International Inc.

发明人： BONNE, Ulrich

IPC分类号： G01N30/12

CPC分类号： G01N35/00871 ,  G01N1/24 ,  G01N1/40 ,  G01N7/16 ,  G01N27/18 ,  G01N30/08 ,  G01N30/12 ,  G01N30/20 ,  G01N30/30 ,  G01N30/461 ,  G01N30/468 ,  G01N30/6095 ,  G01N30/66 ,  G01N30/88 ,  G01N33/225 ,  G01N2001/021 ,  G01N2030/085 ,  G01N2030/121 ,  G01N2030/123 ,  G01N2030/3061 ,  G01N2030/3076 ,  G01N2030/623 ,  G01N2030/642 ,  G01N2035/00881 ,  G01N30/36 ,  G01N30/6052 ,  G01N2030/3015 ,  G01N30/466

摘要： A fluid analyzer having a concentrator and separator for concentrating and separating fluid samples at pressures up to about 10,000 psi (~700 bar). The concentrator and separator may consist of a solid-state thin-film heater-adsorber and a channel supported by a solid substrate. The concentrator may have numerous heated interactive elements for adsorbing and desorbing constituents of a sample fluid. The interactive elements may be heated in a time phased sequential manner by heaters. The separator may separate the sample fluid by compound. There may be thermal conductivity detectors, a flow sensor and electrical conductivity detectors proximate to the channels. This system of concentrator, separator, heaters and sensor may provide information about the sample fluid composition. A pump may be connected to the channel to move the sample fluid through it.

公开(公告)号：EP2329257B1

公开(公告)日：2018-03-07

申请号：EP09803694.0

申请日：2009-07-31

申请人： BioVentures, Inc.,

发明人： DAWSON, Elliott, P.

IPC分类号： G01N30/60 ,  B01L3/00 ,  C12N15/10 ,  B01J20/26 ,  B01J20/28 ,  B01D15/22 ,  B01J20/291 ,  B01J20/283 ,  B01J20/285 ,  G01N30/38

CPC分类号： G01N30/6091 ,  B01D15/22 ,  B01J20/267 ,  B01J20/283 ,  B01J20/285 ,  B01J20/291 ,  B01J2220/58 ,  B01L3/5021 ,  B01L2300/042 ,  B01L2300/0681 ,  B01L2300/0832 ,  G01N30/6052 ,  G01N2030/381 ,  Y10T436/255

摘要： A spin column device, which contains a rigid porous filter that retains its shape during centrifugation and a volume control device, for isolating a desired substance, e.g., a biological molecule, from other substances in a mixture, and a kit containing the device and one or more reagents for use in an isolation or purification procedure.

公开(公告)号：EP3245315A1

公开(公告)日：2017-11-22

申请号：EP15878268.0

申请日：2015-11-13

申请人： Agilent Technologies, Inc.

发明人： CARR, Elizabeth ,  KILLEEN, Kevin

IPC分类号： C23C16/44 ,  B01D15/22 ,  B01D53/04

CPC分类号： B01D15/22 ,  B01D15/206 ,  B01J20/283 ,  B01J20/284 ,  B01J20/3092 ,  B01J20/3234 ,  B01J20/3236 ,  B01J20/3289 ,  C23C16/0272 ,  C23C16/045 ,  C23C16/402 ,  C23C16/405 ,  C23C16/45555 ,  G01N30/6052

摘要： Liquid chromatography and gas chromatography components with a conformal protective coating on internal surfaces thereof and methods for producing the same are provided. The conformal protective coating is formed via an atomic layer deposition (ALD) process. The components and methods of the present disclosure find use in providing protective coatings for liquid chromatography and gas chromatography components that are compatible with bioanalytical separations and sensitive trace analyses.

公开(公告)号：EP3141894A4

公开(公告)日：2017-11-15

申请号：EP15789114

申请日：2015-03-19

申请人： SHOWA DENKO KK

发明人： KONDO HIDEYUKI ,  SASUGA JUNJI ,  SHUKUYA TAKAYUKI

IPC分类号： G01N30/72 ,  B01D15/36 ,  B01D15/38 ,  G01N27/62 ,  G01N30/02 ,  G01N30/26 ,  G01N30/56 ,  G01N30/88

CPC分类号： G01N30/52 ,  B01D15/363 ,  B01D15/3847 ,  G01N27/62 ,  G01N30/02 ,  G01N30/26 ,  G01N30/56 ,  G01N30/6052 ,  G01N30/72 ,  G01N30/7233 ,  G01N30/88 ,  G01N30/96 ,  B01D15/305

摘要： A mass spectrometry method by a liquid chromatograph-mass spectrometer that can detect an organic acid with high sensitivity by retaining, separating and eluting the organic acid without adding any nonvolatile substance to a mobile phase and without receiving any restriction of a ratio of a water-soluble organic solvent, and an analytical column are provided. The mass spectrometry method is a mass spectrometry method for an organic acid by a liquid chromatograph-mass spectrometer, wherein a column packed with a hydrophilic polymer having an anion-exchange group is used, and as a mobile phase, a water-soluble organic solvent-water mixed solution is used. The analytical column is a column for liquid chromatography for an organic acid, in which a polyether ether ketone (PEEK) resin housing for liquid chromatography is packed with a hydrophilic polymer having an anion-exchange group.

公开(公告)号：EP2646817B1

公开(公告)日：2016-05-25

申请号：EP11845091.5

申请日：2011-11-28

申请人： GE Healthcare Bio-Sciences AB

发明人： RAMAKRISHNA, Manoj, Kumar ,  AGNIHOTRY, Shashikanth

IPC分类号： G01N30/60 ,  B01D15/22 ,  B01D15/14

CPC分类号： B01D15/22 ,  G01N30/6004 ,  G01N30/6017 ,  G01N30/6021 ,  G01N30/6026 ,  G01N30/6047 ,  G01N30/6052 ,  Y10T29/49826 ,  Y10T29/49883