公开(公告)号：EP2422202A4

公开(公告)日：2013-04-24

申请号：EP10766705

申请日：2010-04-23

申请人： WALLAC OY

发明人： NICOLAIDES KYPROS ,  AHOLA TARJA

IPC分类号： G01N33/68 ,  G01N33/74

CPC分类号： G01N33/74 ,  G01N2333/475 ,  G01N2800/368

公开(公告)号：EP2382724A1

公开(公告)日：2011-11-02

申请号：EP10702719.5

申请日：2010-01-18

申请人： Wallac OY

发明人： LAITINEN, Jyrki ,  YLI-KOSKI, Antero ,  OJALA, Markku

IPC分类号： H04J3/06 ,  H04L12/40

CPC分类号： H04J3/0644 ,  G01N21/6452 ,  H04L12/40006 ,  H04L2012/40215

摘要： An optical measurement instrument comprises operational modules (101-107) that are interconnected via a digital communication network (110). Each operational module comprises a transceiver (111-117) connected to the digital communication network and arranged to support a pre-determined digital communication protocol employed in the digital communication network. Those operational modules that include a detector further comprise an analog-to-digital converter (118) for converting a detected signal into a digital form and a digital circuitry (119) for providing digital information based on the detected signal with address data related to a particular operational module to which the digital information is to be delivered via the digital communication network. As information is transferred between operational modules via the digital communication network using the pre-determined digital communication protocol, the operational modules can be tested independently of each other using a test bench system arranged to support the pre-determined digital communication protocol.

公开(公告)号：EP2382477A1

公开(公告)日：2011-11-02

申请号：EP10702326.9

申请日：2010-01-18

申请人： Wallac OY

发明人： LAITINEN, Jyrki

IPC分类号： G01N35/02 ,  G01N21/13

CPC分类号： G01N21/13 ,  G01N21/76 ,  G01N2021/6421 ,  G01N2035/00306 ,  G01N2035/0432

摘要： A body module of an optical measurement instrument comprises: a reception de- vice (201) for receiving samples, a first plate (202), a second plate (203) substantially parallel with the first plate and movably supported relative to the first plate in a direction perpendicular to the first and second plates, and walls extending from outer edges of the first plate to outer edges of the second plate. The reception de- vice is located in a measurement chamber constituted by the walls and the first and second plates. At least the second plate comprises a fastening interface provided with an aperture. The fastening interface is suitable for an optical module to be mounted to the second plate. The measuring chamber provides protection against undesired stray light from surroundings. The movability of the second plate allows adjustment of a distance between a sample and an optical module mounted to the second plate.

公开(公告)号：EP2382476A1

公开(公告)日：2011-11-02

申请号：EP10702718.7

申请日：2010-01-18

申请人： Wallac OY

发明人： LAITINEN, Jyrki ,  OJALA, Markku ,  SARMAALA, Jarkko ,  ISAKSSON, Christer

IPC分类号： G01N35/00 ,  G01N21/13

CPC分类号： G01N35/028 ,  G01N21/13 ,  G01N21/6452 ,  G01N2021/6484 ,  G01N2035/0424

摘要： An optical measurement instrument comprises a measurement head (101 ) and mechanical support elements (102, 103) arranged to support a sample plate (106). The measurement head is moved towards the sample plate and, after the measurement head has touched the sample plate, the measurement head is moved backwards away from the sample plate so as to provide a desired distance between the measurement head and the sample plate. A sensor device (112, 113) is attached to the mechanical support elements and arranged detect a mechanical effect occurring in the mechanical support elements due to force directed by the measurement head to the sample plate. Hence, the situation in which the measurement head touches the sample plate can be detected without a need to provide the measurement head with a force sensor. This is advantageous because the measurement head can be a changeable module of the optical measurement instrument.

公开(公告)号：EP2335048A1

公开(公告)日：2011-06-22

申请号：EP09748821.7

申请日：2009-10-01

申请人： Wallac OY

发明人： VÄISÄNEN, Ville ,  KARVINEN, Jarkko ,  HURSKAINEN, Pertti ,  TUOMOLA, Elina

IPC分类号： G01N21/15 ,  G01N21/64 ,  G01N21/90 ,  B01L3/00 ,  C12Q1/48 ,  G01N1/28 ,  G01N33/487

CPC分类号： G01N21/6428 ,  G01N1/286 ,  G01N1/38 ,  G01N21/15 ,  G01N21/6408 ,  G01N21/6452 ,  G01N21/94 ,  G01N35/00663 ,  G01N2021/6432 ,  G01N2021/646

摘要： The invention relates to a method and apparatus for detecting undesired measurement conditions in a sample container. The method comprises measuring a fluorescent property of the sample container comprising a sample substrate with impregnated blood sample and incubation buffer to which the blood sample is to be eluted, and determining, based on temporal and/or spectral characteristics of the fluorescent property, whether the fluorescent property is characteristic to a sample container comprising a sample substrate and incubation buffer under said undesired measurement conditions or to a sample container suitable for optical measurement of analyte contained in the sample. Thus undesired measurement condition can be a floating sample substrate or a foreign body in the sample container. By means of the invention, reliability of neonatal screening, for example, can be increased.

公开(公告)号：EP2245180A1

公开(公告)日：2010-11-03

申请号：EP09704269.1

申请日：2009-01-26

申请人： PerkinElmer Health Sciences, Inc. ,  WALLAC OY ,  The Fetal Medicine Foundation ,  Nicolaides, Kypros

发明人： CUCKLE, Howard ,  NICOLAIDES, Kypros ,  AHOLA, Tarja ,  POON, Leona

IPC分类号： C12Q1/16

CPC分类号： G01N33/689 ,  A61B5/021 ,  G01N33/6893 ,  G01N2333/471 ,  G01N2333/515 ,  G01N2800/368 ,  G01N2800/50 ,  G06F19/00 ,  G06Q50/24 ,  G16H50/30

摘要： The disclosure relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual has for developing pre-eclampsia based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers. The disclosure also relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual is carrying a fetus having a chromosomal abnormality based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers.

公开(公告)号：EP1152010B1

公开(公告)日：2010-04-21

申请号：EP01660078.5

申请日：2001-04-27

申请人： WALLAC OY

发明人： Hovinen, Jari ,  Takalo, Harri

IPC分类号： C07H19/10 ,  C07H19/20 ,  C07H21/00 ,  C07F9/6558 ,  G01N33/53

CPC分类号： C07H19/10 ,  C07F9/582 ,  C07F9/65033 ,  C07F9/65583 ,  C07H19/20 ,  C07H21/00 ,  Y02P20/55

公开(公告)号：EP1517135B1

公开(公告)日：2008-07-30

申请号：EP04396056.6

申请日：2004-08-31

申请人： WALLAC OY

发明人： Harju, Raimo ,  Salonen, Janne ,  Turunen, Hannu

IPC分类号： G01N21/64 ,  G01N21/76 ,  G02B6/26 ,  G01N21/25

CPC分类号： G01N21/763 ,  G01N21/6452 ,  G01N2201/024 ,  G02B6/0001

公开(公告)号：EP0803724B1

公开(公告)日：2008-03-12

申请号：EP97660045.2

申请日：1997-04-22

申请人： WALLAC OY

发明人： Harju, Raimo

IPC分类号： G01N21/25 ,  G01N21/76 ,  G01N21/64 ,  G01N21/59

CPC分类号： G01N21/6408 ,  G01N21/255 ,  G01N21/59 ,  G01N21/645 ,  G01N21/76 ,  G01N30/95 ,  G01N2021/6471

公开(公告)号：EP1842062A1

公开(公告)日：2007-10-10

申请号：EP06700060.4

申请日：2006-01-04

申请人： WALLAC OY

发明人： KUUSISTO, Ari ,  SEV US, Lahja

IPC分类号： G01N33/53 ,  G01N33/569 ,  G01N1/18 ,  C12Q1/68 ,  B01L3/00 ,  C12M1/00

CPC分类号： G01N1/2813 ,  B01L3/50255 ,  G01N2001/2846

摘要： This invention relates a method for analysing a biological sample by imaging, wherein sample processing and detection and optionally pre-treatment is performed in a single container. The invention further relates to a kit for use in said method.