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公开(公告)号：EP2623200A3
公开(公告)日：2014-04-09
申请号：EP13152693.1
申请日：2005-02-01
CPC分类号： F16K99/0001 , B01L3/5025 , B01L3/502723 , B01L3/502738 , B01L3/502746 , B01L3/5088 , B01L2200/0605 , B01L2200/0621 , B01L2300/0681 , B01L2300/0861 , B01L2300/087 , B01L2300/0887 , B01L2400/0406 , B01L2400/0677 , F16K99/0017 , F16K99/0026 , F16K2099/0074
摘要： Für die Untersuchung von Flüssigkeiten in der Biologie, Biochemie, Chemie, Medizin und Pharmazie werden Verfahren angewendet, die mit erheblichem Aufwand für das Handhaben der Flüssigkeiten und für Hilfsmittel verbunden sind, und die eine Mindestmenge an Flüssigkeit benötigen. Die mikrostrukturierte Plattform enthält Hohlräume und Kapillaren, in denen die Flüssigkeit durch Kapillarkraft transportiert wird.
Plattform zum Handhaben einer benetzenden Flüssigkeit, die auf einem mikrostrukturierten Träger- Hohlräume und ein Kanalsystem zum Transport der Flüssigkeit umfasst, das mit mindestens einem Einlass und mit mindestens einem Auslass versehen ist, und der Querschnitt der Kanäle abschnittsweise in Größe und Form unterschiedlich ist, und - die Kanäle als Kapillaren ausgebildet sind, die in mindestens einer Richtung quer zur Transportrichtung der Flüssigkeit mindestens abschnittsweise eine Abmessung im Millimeterbereich und darunter haben, und - die Wände der Mikrostrukturen zumindest bereichsweise benetzbar sind, - wobei die Plattform folgende weitere mikrostrukturierte Elemente umfasst, die im Transportweg der Flüssigkeit angeordnet sind:. einen fluidischen Schalter mit einem Kapillarstopp am Übergang einer engeren Kapillare in eine erweiterte Kapillare, und mit einer Steuerkapillare, die an den Kapillarstopp angeschlossen ist, und . eine Abtrennvorrichtung für einen Flüssigkeitsteilstrom aus einer Dispersion, wobei diese Abtrennvorrichtung einen Kapillarspalt aufweist, der seitlich an einen Kanal angeschlossen ist.摘要翻译： 用于处理润湿液体的板包括用于用入口和出口输送液体的空腔和通道，其中通道具有不同的横截面。 通道是直径在mm区域或以下的毛细管，并且板具有其它液体流动的其它微结构。 用于处理润湿液体的板具有用于输送具有入口和出口的液体的空腔和通道，其中通道具有不同的横截面。 通道是直径在mm区域或以下的毛细管，并且板具有其它液体流动的其它微结构。 它们选自：（a）具有毛细管停止的流体开关，其从窄的毛细管和连接到毛细管止动件的控制毛细管转变; （b）计量单元，其包括毛细管停止件和T形接头与它们之间的液体储存室; （c）分离器，用于将液体与分散体隔离，毛细管间隙连接到通道; 和（d）用于储存预定量的具有与板基部成直角的微结构的液体的区域，其间是与它们大小相当的中间室。
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12.发明公开
公开(公告)号：EP2637933A1
公开(公告)日：2013-09-18
申请号：EP11778595.6
申请日：2011-11-03
发明人： OSTERLOH, Dirk , KUROWSKI, Dirk , RODENFELS, Tobias , BLANKENSTEIN, Gert , EICHMANN, Tobias , HELLMICH-DUONG, Thanh Tu
摘要： The invention relates to a method for filling a cavity of a packaging, in particular a blister packaging, with a liquid and to a packaging that is suitable for this purpose. The cavity is entirely filled by means of an acceleration force or by continuously passing the liquid through said cavity.
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公开(公告)号：EP2624955A1
公开(公告)日：2013-08-14
申请号：EP11767238.6
申请日：2011-10-04
IPC分类号： B01L3/00
CPC分类号： B01L3/50273 , B01L2300/045 , B01L2300/046 , B01L2300/0816 , B01L2400/0481 , B01L2400/0655 , Y10T137/0318
摘要： The invention relates to a microfluidic platform (1) having at least one means (12) for initiating a movement of a liquid (P), in particular sample liquid, between at least two locations (100, 101) of the microfluidic platform (1). It is proposed according to the invention that the means (12) is constructed as an element which is changeable in volume and/or shape, and is mounted on a cover-like component (11) which is moveably connected to the microfluidic platform (1). By moving the component (11), the element (12) can be brought into a position such that, with a change in its volume and/or shape, it has the effect that the liquid (P) that is situated at the location (100) is at least in part moved from this location (100) to the other location (101). In this manner, for example, the transfer of a sample liquid (P) from one sample application site (100) to a sample use region (101) may be effected in a very simple and reliable manner. Furthermore, in the invention, a method is also proposed by which a movement of a liquid between two locations can be initiated, wherein this can be carried out, in particular, using a microfluidic platform (1) according to the invention.
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14.发明公开VORRICHTUNG UND VERFAHREN ZUR ABTRENNUNG VON BESTANDTEILEN EINER PROBENFLÜSSIGKEIT 审中-公开装置和方法用于分离的样品液的成分
公开(公告)号：EP2598242A1
公开(公告)日：2013-06-05
申请号：EP11730285.1
申请日：2011-07-05
IPC分类号： B01L3/00
CPC分类号： B01L3/508 , B01L3/502723 , B01L3/502753 , B01L2200/0621 , B01L2300/0681
摘要： Sample liquid is collected downstream of a separating device in a chamber. A plurality of channels is attached to the chamber, and said channels lead the sample liquid to one or more examination areas.
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公开(公告)号：EP2595751A1
公开(公告)日：2013-05-29
申请号：EP11731312.2
申请日：2011-07-05
发明人： KUROWSKI, Dirk , BLANKENSTEIN, Gert , OSTERLOH, Dirk , PRENGER, Marc , YU, Ying
IPC分类号： B01L3/00
CPC分类号： B01L3/00 , B01L3/502707 , B01L2200/025 , B01L2200/12 , B01L2300/044 , B01L2300/0887 , B23P19/00 , Y10T29/49826 , Y10T29/49865 , Y10T137/7036
摘要： The invention relates to a microfluidic device and to a method for producing same, wherein a film covers a chamber in a carrier. The film is locally tightened in the area of the chamber after attaching the film to the carrier. Undesired bulging of the film into the chamber can thus be avoided.
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16.发明公开
公开(公告)号：EP2560756A1
公开(公告)日：2013-02-27
申请号：EP11711574.1
申请日：2011-04-01
CPC分类号： G01N1/28 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502746 , B01L3/502753 , B01L2200/027 , B01L2300/0681 , B01L2300/0851 , B01L2300/087 , B01L2300/0887 , B01L2400/0406 , B29C65/548 , G01N33/491 , G01N33/492
摘要： The invention relates to a device for sample separation, in particular for blood separation, wherein the sample liquid is added to a feeding unit. The sample flows in the vertical direction through a separation unit such as a filter or a membrane, whereby sample particles are retained and separated. The sample liquid thus separated, in particular blood plasma, is received by an inlet chamber underneath the separation unit and is discharged from the inlet chamber in the lateral direction by means of a channel. Particularly advantageously, the channel extends into the inlet chamber, wherein the channel is formed by a recess in the bottom of the inlet chamber.
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公开(公告)号：EP2451575A2
公开(公告)日：2012-05-16
申请号：EP10726046.5
申请日：2010-06-08
IPC分类号： B01L3/00
CPC分类号： B01L3/502738 , B01L3/50273 , B01L3/502746 , B01L3/502753 , B01L2200/0605 , B01L2200/0621 , B01L2200/0684 , B01L2300/0681 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2300/165 , B01L2400/0406 , B01L2400/0487 , B01L2400/0688 , B01L2400/086 , B01L2400/088 , G01N33/491 , Y10T137/0318 , Y10T137/794
摘要： The invention relates to a microfluidic apparatus for producing a volume flow that is uniform over time in a metering process. In various solution processes or reaction processes it is essential to have a specified given volume flow or mass flow of fluid available to ensure reliable dissolution of the reagent or ensure that the reaction takes place. In microfluidic apparatus in which separation of particles from a fluid, particularly blood, is carried out through a membrane, the volume flow through the membrane decreases continuously. In order to achieve a uniform volume flow during metering, it is envisaged that first of all a reservoir is filled from a first channel, so that the contents of the reservoir can then be fed to the metering process by opening a fluid stop. The emptying of the reservoir takes place with a uniform volume flow of 0.05 microliters per second to 10 microliters per second.
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公开(公告)号：EP1802356B1
公开(公告)日：2012-01-04
申请号：EP05762274.8
申请日：2005-07-19
CPC分类号： A61L9/145 , A61L9/12 , A61L2209/22
摘要： A discharge device and a method for evaporating a liquid to the atmosphere are proposed. The liquid pressurized by gas is supplied to an evaporator (7) via a flow restriction device (5) which restricts the flow rate of the liquid such that continuous release and evaporation surface which is designed preferably by micro structuring such that the surface area is increased and/or the liquid forms an essentially uniform film on the evaporation surface.
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19.发明公开
公开(公告)号：EP2010230A2
公开(公告)日：2009-01-07
申请号：EP07724552.0
申请日：2007-04-25
摘要： Discharge device for dispensing fragrance or the like comprising capillary tube for supplying liquid from reservoir to an evaporator's surface. The capillary has specific geometric properties concerning hydraulic diameter and length. In the capillary's flow channel a valve, filter or constriction may be integrated. Further, an evaporator is disclosed comprising a capillary for supplying the evaporation surface with liquid. The surface comprises micro-channels for uniform fluid film formation.
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公开(公告)号：EP1899702A2
公开(公告)日：2008-03-19
申请号：EP06742544.7
申请日：2006-04-07
发明人： BALLHORN, Ilse , BLANKENSTEIN, Gert , PETERS, Ralf-Peter , MÜLLER-CHORUS, Birgit , SCHLÜTER, Michael
CPC分类号： B01F13/0059 , B01L3/5025 , B01L3/50273 , B01L2200/0605 , B01L2200/0621 , B01L2300/0806 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2400/0406 , B01L2400/0409 , B01L2400/0688 , Y10T436/25375 , Y10T436/2575
摘要： Disclosed are a device and a method for analyzing a sample liquid, particularly the ELISA method being very easy, fast, and highly accurate to carry out. According to the invention, a sample liquid and a diluting liquid are fed to several dosing chambers having different volumes such that the sample liquid can be diluted into associated reaction chambers at different dilution ratios in a dilution step. Different liquids can be delivered successively to the reaction chambers by means of a common receiving chamber. The liquids are transferred from the reaction chambers into associated test chambers in order to stop the detection reaction.
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