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公开(公告)号：EP1518604B1
公开(公告)日：2018-06-13
申请号：EP04021864.6
申请日：2004-09-15
Applicant: Boehringer Ingelheim microParts GmbH
Inventor： Kadel, Klaus, Dr. , Blankenstein, Gert, Dr.
CPC classification number: F16K99/0017 , B01L3/5025 , B01L3/502738 , B01L3/5085 , B01L3/523 , B01L2200/16 , B01L2300/044 , B01L2300/047 , B01L2300/0672 , B01L2400/0638 , B01L2400/065 , F16K99/0001 , F16K99/003 , F16K99/0034 , Y10T436/2575
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2.发明授权FLUIDISCHES SYSTEM UMFASSEND EINE PORÖSE MEMBRAN MIT VERÄNDERBARER PORENOBERFLÄCHE UND VERFAHREN ZUM BETREIBEN DESSELBEN 有权包括具有可变孔隙界面的多孔膜的流体系统和用于操作相同的方法
公开(公告)号：EP2830764B1
公开(公告)日：2018-05-09
申请号：EP13712297.4
申请日：2013-03-27
Inventor： BASSLER, Michael , DRESE, Klaus, Stefan , LATTA, Daniel
CPC classification number: F16K99/0017 , B01D35/06 , B01D61/18 , B01D61/22 , B01L3/502715 , B01L3/502738 , B01L3/502746 , B01L3/502769 , B01L2200/0673 , B01L2200/146 , B01L2300/0681 , B01L2300/161 , B01L2400/0427 , B01L2400/088 , F16K99/0025 , F16K99/004 , F16K99/0042 , F16K2099/0084 , G02B26/005 , Y10T137/2191 , Y10T137/2196
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公开(公告)号：EP2786019A4
公开(公告)日：2015-09-16
申请号：EP12849108
申请日：2012-10-17
Applicant: IBM , CORIS BIOCONCEPT SPRL
Inventor： AVRAIN LAETITIA , DELAMARCHE EMMANUEL , HITZBLECK MARTINA , LAURENT THIERRY , MERTENS PASCAL , SMEKENS VALÉRIE
CPC classification number: B01L3/00 , B01L3/502738 , B01L3/502746 , B01L7/52 , B01L2200/0684 , B01L2300/0816 , B01L2300/0864 , B01L2300/14 , B01L2400/0406 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , B01L2400/0688 , B01L2400/082 , B01L2400/086 , F16K99/0001 , F16K99/0015 , F16K99/0017 , F16K99/0026 , F16K2099/008 , F16K2099/0084
Abstract: A microfluidic device includes a first microchannel, a second microchannel, and a valve comprising at least an input port and an output port, the ports respectively connected to the first microchannel and the second microchannel, the valve designed to control a flow of a liquid along a flow direction (z) defined by the ports; wherein the valve further comprises one or more walls joining the ports and defining a hollow chamber that is wider than each of the microchannels in a direction perpendicular to the flow direction, the walls at least partly deformable along a deformation direction (−y) intersecting the flow direction, such that the walls can be given at least a first deformation state and a second deformation state, such that the liquid can be pulled along the flow direction substantially more in the second deformation state than in the first deformation state.
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公开(公告)号：EP2869923A2
公开(公告)日：2015-05-13
申请号：EP13719514.5
申请日：2013-04-25
Applicant: Scope Fluidics SP. Z O.O.
Inventor： KORCZYK, Piotr , DERZSI, Ladislav , KAMINSKI, Tomasz , JAKIELA, Slawomir , GARSTECKI, Piotr
CPC classification number: B01L3/502784 , B01F13/0071 , B01F13/0083 , B01L3/502738 , B01L3/502746 , B01L7/525 , B01L2200/0605 , B01L2200/0621 , B01L2200/0673 , B01L2200/0684 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/088 , B01L2400/0406 , B01L2400/0688 , B01L2400/086 , F16K99/0017 , F16K99/0021 , F16K2099/0084
Abstract: The invention provides a new microfluidic device and method for performing operations on droplets. The invention extends to microfluidic systems comprising one or more of the microfluidic devices.
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公开(公告)号：EP2623200A3
公开(公告)日：2014-04-09
申请号：EP13152693.1
申请日：2005-02-01
Applicant: Boehringer Ingelheim microParts GmbH
Inventor： BLANKENSTEIN, Gert , MARQUORDT, Claus , BARTOS, Holger , WILLMS, Thomas , PETERS, Ralf-Peter
CPC classification number: F16K99/0001 , B01L3/5025 , B01L3/502723 , B01L3/502738 , B01L3/502746 , B01L3/5088 , B01L2200/0605 , B01L2200/0621 , B01L2300/0681 , B01L2300/0861 , B01L2300/087 , B01L2300/0887 , B01L2400/0406 , B01L2400/0677 , F16K99/0017 , F16K99/0026 , F16K2099/0074
Abstract: Für die Untersuchung von Flüssigkeiten in der Biologie, Biochemie, Chemie, Medizin und Pharmazie werden Verfahren angewendet, die mit erheblichem Aufwand für das Handhaben der Flüssigkeiten und für Hilfsmittel verbunden sind, und die eine Mindestmenge an Flüssigkeit benötigen. Die mikrostrukturierte Plattform enthält Hohlräume und Kapillaren, in denen die Flüssigkeit durch Kapillarkraft transportiert wird.
Plattform zum Handhaben einer benetzenden Flüssigkeit, die auf einem mikrostrukturierten Träger- Hohlräume und ein Kanalsystem zum Transport der Flüssigkeit umfasst, das mit mindestens einem Einlass und mit mindestens einem Auslass versehen ist, und der Querschnitt der Kanäle abschnittsweise in Größe und Form unterschiedlich ist, und - die Kanäle als Kapillaren ausgebildet sind, die in mindestens einer Richtung quer zur Transportrichtung der Flüssigkeit mindestens abschnittsweise eine Abmessung im Millimeterbereich und darunter haben, und - die Wände der Mikrostrukturen zumindest bereichsweise benetzbar sind, - wobei die Plattform folgende weitere mikrostrukturierte Elemente umfasst, die im Transportweg der Flüssigkeit angeordnet sind:. einen fluidischen Schalter mit einem Kapillarstopp am Übergang einer engeren Kapillare in eine erweiterte Kapillare, und mit einer Steuerkapillare, die an den Kapillarstopp angeschlossen ist, und . eine Abtrennvorrichtung für einen Flüssigkeitsteilstrom aus einer Dispersion, wobei diese Abtrennvorrichtung einen Kapillarspalt aufweist, der seitlich an einen Kanal angeschlossen ist.Abstract translation: 用于处理润湿液体的板包括用于用入口和出口输送液体的空腔和通道，其中通道具有不同的横截面。 通道是直径在mm区域或以下的毛细管，并且板具有其它液体流动的其它微结构。 用于处理润湿液体的板具有用于输送具有入口和出口的液体的空腔和通道，其中通道具有不同的横截面。 通道是直径在mm区域或以下的毛细管，并且板具有其它液体流动的其它微结构。 它们选自：（a）具有毛细管停止的流体开关，其从窄的毛细管和连接到毛细管止动件的控制毛细管转变; （b）计量单元，其包括毛细管停止件和T形接头与它们之间的液体储存室; （c）分离器，用于将液体与分散体隔离，毛细管间隙连接到通道; 和（d）用于储存预定量的具有与板基部成直角的微结构的液体的区域，其间是与它们大小相当的中间室。
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Patent Agency Ranking
公开(公告)号：EP1946830A4
公开(公告)日：2012-09-19
申请号：EP06821911
申请日：2006-10-18
Applicant: KONICA MINOLTA MED & GRAPHIC
Inventor： HIGASHINO KUSUNOKI , SANDO YASUHIRO , NAKAJIMA AKIHISA , AOKI YOUICHI
CPC classification number: B01L3/502738 , B01F5/0602 , B01F5/0647 , B01F13/0059 , B01J19/0093 , B01J2219/00891 , B01L3/502723 , B01L3/502746 , B01L2200/0684 , B01L2200/16 , B01L2300/0816 , B01L2300/0867 , B01L2300/1822 , B01L2400/0439 , B01L2400/0487 , B01L2400/0688 , B01L2400/084 , F16K99/0001 , F16K99/0017 , F16K99/0034 , F16K99/0057 , F16K2099/0084 , Y10T436/2575
Abstract: A microreactor capable of reaction between a sample and a mixed reagent consisting of a mixture of multiple reagents, which microreactor avoids the interposition of air between driven liquid and reagents and realizes high-precision controlling of the timing of mixing of reagents and other liquids, the mixing ratio of liquids, the pressure for liquid delivery, etc. Further, there is provided a method of liquid feeding making use of the same. Accordingly, flow channel (45a) branched at the position of infusion aperture (34b) from flow channel (45) by which opening (32) communicating with an external pump communicates with the infusion aperture (34b) is fitted with air vent flow channel (46) with its terminal open outward. Further, the flow channel resistance at flow of liquid through the air vent flow channel (46) is made greater than the flow channel resistance at flow of liquid through flow channel (44) from reagent accommodation part (33) starting from the branching portion of the branched flow channel (45a) to reagent delivery flow channel (43).
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公开(公告)号：EP1987353B1
公开(公告)日：2012-06-13
申请号：EP07705600.0
申请日：2007-02-15
Applicant: Universal Biosensors PTY Limited
CPC classification number: F16K99/0017 , B01L3/502738 , B01L2200/143 , B01L2300/0645 , B01L2300/0816 , B01L2300/0825 , B01L2300/0874 , B01L2300/0887 , B01L2400/0406 , B01L2400/0487 , B01L2400/0688 , F16K99/0001 , F16K99/0025 , F16K2099/008 , F16K2099/0086 , Y10T436/25 , Y10T436/2575
Abstract: A microfluidic device for transferring liquid from a first chamber to a second chamber is provided. The device has a first chamber; a second chamber; and a barrier between the first chamber and the second chamber, the barrier having least one opening fluidly connecting the first chamber to the second chamber, the at least one opening being sized suc that a retention force, such as surface tension, keeps the liquid in the first chamber. The fluid is transferred from the first chamber to the second chamber when an initiation input such as fluid pressure is introduced to the liquid that is sufficient to overcome the retention force. The device may be a sensor strip.
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公开(公告)号：EP2337981A1
公开(公告)日：2011-06-29
申请号：EP09787146.1
申请日：2009-09-09
Applicant: Koninklijke Philips Electronics N.V.
Inventor： DEN TOONDER, Jacob, M., J. , REIJME, Mirielle, A. , PONJEE, Marc, W., G. , GILLIES, Murray, F.
CPC classification number: F16K99/0001 , B01L3/502738 , B01L2400/0484 , B01L2400/0633 , B01L2400/0661 , B01L2400/0688 , F16K99/0017 , F16K99/0034 , F16K2099/008 , F16K2099/0084 , Y10T29/494 , Y10T137/0318
Abstract: The present invention provides a microfluidic device. The microfluidic device comprises a first fluidic compartment(10) and a second fluidic compartment (11). The microfluidic device furthermore comprises at least one micromechanical actuator element (14) for, when in use, forcing a sample fluid to flow from the first fluidic compartment (10) into the second fluidic compartment (11).
Abstract translation: 本发明提供了一种微流体装置。 微流体装置包括第一流体室（10）和第二流体室（11）。 微流体装置还包括至少一个微机械致动器元件（14），用于在使用时迫使样品流体从第一流体室（10）流入第二流体室（11）。
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公开(公告)号：EP2247526A1
公开(公告)日：2010-11-10
申请号：EP09704874.8
申请日：2009-01-26
Applicant: Mphase Technologies, Inc.
Inventor： SIMON, Steve , LIFTON, Victor
CPC classification number: B01L3/5023 , B01L3/502707 , B01L3/50273 , B01L2300/0816 , B01L2400/0427 , F16K99/0017 , F16K99/0025 , F16K99/0042 , F16K2099/008 , Y10T29/494 , Y10T137/0391 , Y10T137/212 , Y10T137/2125
Abstract: A fluidic device includes a porous substrate, a wetting region extending through a first portion of the porous substrate from a first side of the substrate, in which the wetting region is permeable to fluid transport, and a non-wetting region extending through a second portion of the porous substrate from a second side of the substrate, in which the non-wetting region is operable to switch between a first state impermeable to fluid transport and a second state permeable to fluid transport.
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公开(公告)号：EP1946830A1
公开(公告)日：2008-07-23
申请号：EP06821911.2
申请日：2006-10-18
Applicant: Konica Minolta Medical & Graphic, Inc.
Inventor： HIGASHINO, Kusunoki , SANDO, Yasuhiro , NAKAJIMA, Akihisa , AOKI, Youichi
CPC classification number: B01L3/502738 , B01F5/0602 , B01F5/0647 , B01F13/0059 , B01J19/0093 , B01J2219/00891 , B01L3/502723 , B01L3/502746 , B01L2200/0684 , B01L2200/16 , B01L2300/0816 , B01L2300/0867 , B01L2300/1822 , B01L2400/0439 , B01L2400/0487 , B01L2400/0688 , B01L2400/084 , F16K99/0001 , F16K99/0017 , F16K99/0034 , F16K99/0057 , F16K2099/0084 , Y10T436/2575
Abstract: A microreactor capable of reaction between a sample and a mixed reagent consisting of a mixture of multiple reagents, which microreactor avoids the interposition of air between driven liquid and reagents and realizes high-precision controlling of the timing of mixing of reagents and other liquids, the mixing ratio of liquids, the pressure for liquid delivery, etc. Further, there is provided a method of liquid feeding making use of the same. Accordingly, flow channel (45a) branched at the position of infusion aperture (34b) from flow channel (45) by which opening (32) communicating with an external pump communicates with the infusion aperture (34b) is fitted with air vent flow channel (46) with its terminal open outward. Further, the flow channel resistance at flow of liquid through the air vent flow channel (46) is made greater than the flow channel resistance at flow of liquid through flow channel (44) from reagent accommodation part (33) starting from the branching portion of the branched flow channel (45a) to reagent delivery flow channel (43).
Abstract translation: 能够在样品和由多种试剂的混合物组成的混合试剂之间进行反应的微反应器，该微反应器避免在驱动液体和试剂之间插入空气，并实现对试剂和其它液体的混合时间的高精度控制， 液体的混合比，液体输送的压力等。此外，提供了使用该液体的液体供给的方法。 因此，从流路（45）位于输液口（34b）的位置处分支的流路（45a）通过与外部泵连通的开口（32）与输注孔（34b）连通，配合有排气流通道 46），其端子向外打开。 此外，通过排气流通道（46）的液体流动的流动通道阻力大于从试剂容纳部分（33）的液体通过流动通道（44）流动的流动通道阻力，其从分支部分 分支流路（45a）到试剂输送流路（43）。
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