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公开(公告)号：EP1594447A2
公开(公告)日：2005-11-16
申请号：EP03786510.2
申请日：2003-09-29
申请人： GENENTECH, INC.
发明人： WU, Thomas, D. , ZHANG, Zemin , ZHOU, Yan
IPC分类号： A61K7/00
CPC分类号： C07K16/30 , C07K14/47 , C12Q1/6886 , C12Q2600/136
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：EP1234036A2
公开(公告)日：2002-08-28
申请号：EP00991686.7
申请日：2000-11-10
申请人： Genentech, Inc.
发明人： FONG, Sherman , GODDARD, Audrey , GODOWSKI, Paul, J. , GRIMALDI, Christopher, J. , GURNEY, Austin, L. , HILLAN, Kenneth, J. , TUMAS, Daniel , WATANABE, Colin, K. , WOOD, William, I. , ZHANG, Zemin
IPC分类号： C12N15/12 , C07K14/47 , C12N15/62 , C07K16/18 , A61K38/17 , A61K39/395 , G01N33/53 , C12Q1/68
CPC分类号： A61K38/17 , A61K39/395 , C07K14/47 , C07K16/18 , C12N15/62 , C12Q1/68 , G01N33/53 , Y02A50/464
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
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公开(公告)号：EP1169442B1
公开(公告)日：2006-06-07
申请号：EP00917717.1
申请日：2000-03-01
申请人： GENENTECH, INC.
发明人： DESNOYERS, Luc , EATON, Dan, L. , GODDARD, Audrey , GODOWSKI, Paul, J. , GURNEY, Austin, L. , PAN, James , STEWART, Timothy, A. , WATANABE, Colin, K. , WOOD, William, I. , ZHANG, Zemin
CPC分类号： C07K14/70578 , C07K14/47 , C07K2319/00
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公开(公告)号：EP1639000A2
公开(公告)日：2006-03-29
申请号：EP04777475.7
申请日：2004-07-02
申请人： GENENTECH, INC.
发明人： ASHKENAZI, Avi , CAIRNS, Belinda , DOWD, Patrick , FRANTZ, Gretchen , FRENCH, Dorothy , GONZALEZ, Lino , POLAKIS, Paul , SMITH, Victoria , WOLF, Beni , WU, Thomas, D. , ZHANG, Zemin
IPC分类号： C07K14/47
CPC分类号： C07K16/30 , A61K47/6803 , A61K47/6809 , A61K47/6843 , A61K47/6851 , A61K2039/505
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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15.发明公开IDENTIFICATION OF CELLULAR POLYPEPTIDES DIFFERENTIALLY EXPRESSED BY TUMOR CELLS 审中-公开识别细胞多肽具有肿瘤细胞中差异表达HAVE
公开(公告)号：EP1589997A2
公开(公告)日：2005-11-02
申请号：EP04708670.7
申请日：2004-02-05
申请人： GENENTECH, INC.
发明人： FRANTZ, Gretchen , HILLAN, Kenneth , POLAKIS, Paul , WOLF, Beni , WU, Thomas , ZHANG, Zemin
IPC分类号： A61K39/395 , A61P35/00 , A61K47/48
CPC分类号： C07K16/30
摘要： The present invention is directed to the identification of various cellular polypeptides (and their encoding nucleic acids or fragments thereof) which are expressed to a greater degree on the surface of or by one or more types of cancer cell(s) as compared to on the surface of or by one or more types of normal non-cancer cells. Alternatively, such polypeptides are expressed by cells which produce and/or secrete polypeptides having a potentiating or growth-enhancing effect on cancer cells. Again alternatively, such polypeptides may not be overexpressed by tumor cells as compared to normal celles of the same tissue type, but rather may be specifically expressed by both tumor cells and normal cells of only a single or very limited number of tissue types (preferably tissues which are not essential for life, e.g. prostate, etc.).
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16.发明公开
公开(公告)号：EP1589933A2
公开(公告)日：2005-11-02
申请号：EP03783432.2
申请日：2003-11-13
申请人： GENENTECH, INC.
发明人： ASHKENAZI, Avi J. , FRANTZ, Gretchen , GODDARD, Audrey , GONZALEZ, Lino , GURNEY, Austin L. , POLAKIS, Paul , POLSON, Andrew , WOOD, William I. , WU, Thomas D. , ZHANG, Zemin
IPC分类号： A61K7/00
CPC分类号： C07K16/30 , A61K2039/505
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公开(公告)号：EP1397383A2
公开(公告)日：2004-03-17
申请号：EP01990229.5
申请日：2001-12-13
申请人： Genentech, Inc.
发明人： GODDARD, Audrey , WOOD, William I. , YE, Weilan , ZHANG, Zemin
IPC分类号： C07K14/47 , C12N15/12 , C12N15/62 , C07K16/18 , A61K38/17 , A61K39/395 , C12Q1/68 , G01N33/68
CPC分类号： C12Q1/6883 , A61K38/00 , C07K14/47 , C12Q2600/158 , G01N33/6893 , G01N2800/10
摘要： The present invention is directed to a novel polypeptide and to nucleic acid molecules encoding that polypeptide. Also provided herein are methods of treating and diagnosing bone disorders.
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18.发明公开
公开(公告)号：EP1311668A2
公开(公告)日：2003-05-21
申请号：EP01966255.0
申请日：2001-08-23
申请人： GENENTECH, INC.
发明人： ASHKENAZI, Avi, J. , GODDARD, Audrey , GODOWSKI, Paul, J. , GURNEY, Austin, L. , POLAKIS, Paul , WILLIAMS, P., Mickey , WOOD, William, I. , WU, Thomas, D. , ZHANG, Zemin
CPC分类号： A61K38/20 , C07K14/54 , C07K14/7155 , C12N15/1136 , C12N2310/11 , C12N2310/12 , C12N2310/15
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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19.发明公开
公开(公告)号：EP1210418A1
公开(公告)日：2002-06-05
申请号：EP00916675.2
申请日：2000-03-30
申请人： Genentech Inc.
发明人： ASHKENAZI, Avi, J , BAKER, Kevin P. , BOTSTEIN, David , DESNOYERS, Luc , EATON, Dan,L. , FERRARA, Napoleone , GERBER, Hanspeter , GERRITSEN, Mary,E , GODDARD, Audrey , GODOWSKI, PaulJ. , GRIMALDI, Christipher, J , GURNEY, Austin, L. , KLJAVIN, Ivar,J. , NAPIER,Mary, A , PAN, James , PAONI, Nicholas F. , ROY, Margaret,Ann , STEWART, Timothy, A , TUMAS, Daniel , WATANABE, Colin, K , WILLIAMS, P.,Mickey , WOOD, William, I , ZHANG, Zemin
CPC分类号： A61K38/17 , C07K14/005 , C07K14/47 , C07K14/705 , C07K16/18 , C12N2710/16222
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：EP1578760B1
公开(公告)日：2014-02-12
申请号：EP03749460.6
申请日：2003-09-05
申请人： Genentech, Inc.
CPC分类号： C12N9/12 , A61K38/00 , C12N9/1205 , C12N2310/14
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