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1.发明授权
公开(公告)号：EP1812465B1
公开(公告)日：2016-09-07
申请号：EP04822633.6
申请日：2004-11-12
申请人： Genentech, Inc.
发明人： CLARK, Hilary , EATON, Daniel L. , WRANIK, Bernd , OUYANG, Wenjun , GONZALEZ, Lino , LOYET, Kelly M. , GURNEY, Austin L.
IPC分类号： C07K14/47 , A61K38/16 , A61K39/395 , C07K16/28
CPC分类号： C07K14/47 , A61K38/00 , A61K2039/505 , C07K16/2818 , C12N2799/026
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公开(公告)号：EP1589933A2
公开(公告)日：2005-11-02
申请号：EP03783432.2
申请日：2003-11-13
申请人： GENENTECH, INC.
发明人： ASHKENAZI, Avi J. , FRANTZ, Gretchen , GODDARD, Audrey , GONZALEZ, Lino , GURNEY, Austin L. , POLAKIS, Paul , POLSON, Andrew , WOOD, William I. , WU, Thomas D. , ZHANG, Zemin
IPC分类号： A61K7/00
CPC分类号： C07K16/30 , A61K2039/505
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3.发明授权
公开(公告)号：EP1560593B1
公开(公告)日：2016-04-20
申请号：EP03711193.7
申请日：2003-02-19
申请人： Genentech, Inc.
发明人： CLARK, Hilary , EATON, Dan L. , GURNEY, Austin L. , WRANIK, Bernd
IPC分类号： A61K38/00 , G01N33/50 , G01N33/574 , G01N33/68 , C07K14/705 , C07K16/28
CPC分类号： C07K14/705 , A61K38/00 , C07K16/28 , C07K2319/00 , G01N33/5011 , G01N33/57407 , G01N33/6893 , G01N2333/705 , G01N2800/065 , G01N2800/24 , G01N2800/245
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公开(公告)号：EP2084188A2
公开(公告)日：2009-08-05
申请号：EP07871155.3
申请日：2007-10-11
申请人： Genentech, Inc.
IPC分类号： C07K16/24 , A61K39/395 , A61P37/06 , C07K14/525
CPC分类号： C07K16/242 , A61K2039/505 , C07K2317/24 , C07K2317/41 , C07K2317/565 , C07K2317/567 , C07K2317/732 , C07K2317/76 , C07K2317/92 , G06Q99/00
摘要： The invention provides various antibodies that bind to lymphotoxin-α, methods for making such antibodies, compositions and articles incorporating such antibodies, and their uses in treating, for example, an autoimmune disorder. The antibodies include murine, chimeric, and humanized antibodies
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公开(公告)号：EP1250426A2
公开(公告)日：2002-10-23
申请号：EP00983846.7
申请日：2000-12-01
申请人： Genentech Inc.
发明人： BAKER, Kevin P. , BERESINI, Maureen , DEFORGE, Laura , DESNOYERS, Luc , FILVAROFF, Ellen , GAO, Wei-Qiang , GERRITSEN, Mary E. , GODDARD, Audrey , GODOWSKI, Paul J. , GURNEY, Austin L. , SHERWOOD, Steven , SMITH, Victoria , STEWART, Timothy A. , TUMAS, Daniel , WATANABE, Colin K. , WOOD, William L. , ZHANG, Zemin
IPC分类号： C12N15/12 , C07K14/47 , C07K14/705 , C12N15/62 , C07K16/18 , C07K16/28 , G01N33/53 , A61K38/17 , C12Q1/68
CPC分类号： C07K14/4748 , A61K38/00 , C07K14/47
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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6.发明公开
公开(公告)号：EP2056860A2
公开(公告)日：2009-05-13
申请号：EP07864668.4
申请日：2007-11-20
申请人： Genentech, Inc.
发明人： GURNEY, Austin L. , BALAZS, Mercedes , GHILARDI, Nico , HYMOWITZ, Sarah , HASS, Philip , STAROVASNIK, Melissa , WU, Yan , LEE, James M. , ARNOTT, David , OUYANG, Wenjun
CPC分类号： C07K16/244 , A61K38/2073 , A61K2039/505 , C07K14/54 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/76 , C07K2317/92 , C07K2319/30 , C07K2319/40 , G01N2500/10 , G01N2800/24 , Y02A50/463
摘要： The present invention is directed to a novel naturally occurring human cytokine that is comprised of a heterodimer of interleukin-17 and interleukin-17F designated herein as interleukin 17A/F (IL-17 A/F). Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, specific antibodies which bind to the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
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公开(公告)号：EP1576137A2
公开(公告)日：2005-09-21
申请号：EP03796358.4
申请日：2003-10-28
申请人： GENENTECH, INC.
发明人： AGGARWAL, Sudeepta , CLARK, Hilary , GURNEY, Austin L. , SCHOENFELD, Jill , WILLIAMS, P. Mickey , WOOD, William I. , WU, Thomas D.
IPC分类号： C12N1/00
CPC分类号： C07K14/47 , A61K38/00 , Y02A50/463
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
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8.发明公开SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME 审中-公开SEKRETIERTE-和TRANSMEMBRANPOLYPEPTIDE和核酸编码
公开(公告)号：EP1341814A2
公开(公告)日：2003-09-10
申请号：EP01985272.2
申请日：2001-08-29
申请人： GENENTECH, INC.
发明人： BAKER, Kevin P. , EATON, Dan L. , FILVAROFF, Ellen , GODDARD, Audrey , GRIMALDI, J. Christopher , GURNEY, Austin L. , SMITH, Victoria , STEPHAN, Jean-Philippe , WATANABE, Colin K. , WOOD, William I. , ZHANG, Zemin , FONG, Sherman
CPC分类号： C07K14/47 , C07K14/705
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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9.发明公开
公开(公告)号：EP1263948A2
公开(公告)日：2002-12-11
申请号：EP00907314.9
申请日：2000-02-18
申请人： Genentech, Inc.
发明人： ASZKENAZI, Avi J. , BAKER, Kevin P. , BOTSTEIN, David , DESNOYERS, Luc , EATON, Dan L. , FERRARA, Napoleone , FILVAROFF, Ellen , FONG, Sherman , GAO, Wei-Qiang , GERBER, Hanspeter , GERRITSEN, Mary E. , GODDARD, Audrey , GODOWSKI, Paul J. , GRIMALDI, Christopher G. , GURNEY, Austin L. , HILLAN, Kenneth J. , KLJAVIN, Ivar J. , KUO, Sophia S. , NAPIER, Mary A. , PAN, James , PAONI, Nicholas F. , ROY, Margaret Ann , SHELTON, David L. , STEWART, Timothy A. , TUMAS, Daniel , WILLIAMS, P. Mickey , WOOD, William I.
IPC分类号： C12N15/12 , C12N15/63 , C12N5/10 , C12N1/21 , C12N1/19 , C07K14/47 , C07K14/705 , C07K19/00 , C07K16/18 , C07K16/28 , G01N33/68 , G01N33/543 , A61K47/48 , A61K51/08 , A61K38/17
CPC分类号： C07K16/18 , A61K38/00 , A61K47/64 , C07K14/47 , C07K14/4703 , C07K14/705 , C07K14/70578 , C07K16/28 , C07K2317/24 , C07K2319/00 , C12N2799/026 , C12N2799/027
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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10.发明公开COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF INFLAMMATORY BOWEL DISORDERS 审中-公开组合物和方法进行诊断和治疗炎症性肠病
公开(公告)号：EP1578385A2
公开(公告)日：2005-09-28
申请号：EP02786421.4
申请日：2002-10-15
申请人： GENENTECH, INC.
发明人： GODDARD, Audrey , GURNEY, Austin L.
IPC分类号： A61K7/00
CPC分类号： C07K16/28 , A61K47/6843 , A61K51/1018 , A61K51/1027 , C07K14/4713 , C07K14/705 , C12Q1/6876 , C12Q1/6883 , C12Q2600/136 , C12Q2600/158 , G01N33/53 , G01N2800/065
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