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24 条记录 (耗时 0.01 秒)

    NOVEL BASE COMPOSITION FOR TAPE AGENT
    11.
    发明公开
    NOVEL BASE COMPOSITION FOR TAPE AGENT 审中-公开
    新的基于组成一个乐队资源

    公开(公告)号：EP3045166A4

    公开(公告)日：2016-09-07

    申请号：EP14843847

    申请日：2014-09-10

    申请人： MEDRX CO LTD

    发明人： HAMAMOTO HIDETOSHI ,  YAMANAKA KATSUHIRO ,  TANIMOTO TAKAHIRO

    IPC分类号： A61K9/70 ,  A61K31/165 ,  A61K31/7088 ,  A61K38/00 ,  A61K39/00 ,  A61K45/00 ,  A61K47/04 ,  A61K47/12 ,  A61K47/18 ,  A61K47/26 ,  A61K47/32 ,  A61K47/36 ,  A61K47/38

    CPC分类号： A61K9/7053 ,  A61K31/165 ,  A61K31/485 ,  A61K38/00 ,  A61K45/00

    摘要： The object of the present invention is to provide a composition for a non-aqueous patch preparation having an excellent adhesibility which can sustainedly release a drug. The patch preparation of the present invention can improve the adhesibility thereof as well as the release property of a drug by the addition of powder ingredient (e.g. a filler). As a result, the long-time sustention of the adhesibility of patch preparations can achieve the improvement of the transdermal absorbability and the sustained release of a drug. By the use of a composition for a patch preparation comprising this powder ingredient, a drug, regardless of the type of a drug is dissolved in an organic solvent or an ionic liquid to prepare a drug solution comprising the organic solvent, the drug solution is incorporated into the non-aqueous patch preparation of the present invention, and thereby a preparation with the improved transdermal-absorbability and sustained release can prepared.

    MICRONEEDLE AND MICRONEEDLE ARRAY
    12.
    发明公开
    MICRONEEDLE AND MICRONEEDLE ARRAY 审中-公开
    微针和微针场

    公开(公告)号：EP2842595A4

    公开(公告)日：2015-12-09

    申请号：EP13782340

    申请日：2013-04-24

    申请人： TEIJIN LTD ,  MEDRX CO LTD

    发明人： TOYOHARA KIYOTSUNA ,  TANAKA TAISHI ,  KOHNO KAZUTERU ,  ODA TAKASHI ,  MASAOKA KOICHI ,  KOBAYASHI KATSUNORI ,  ISHIBASHI MASAKI ,  HAMAMOTO HIDETOSHI

    IPC分类号： A61M37/00 ,  A61K9/00

    CPC分类号： A61M37/0015 ,  A61K9/0021 ,  A61M2037/0046 ,  A61M2037/0053 ,  A61M2037/0061

    摘要： A microneedle and a microneedle array which can support not only a drug but also a stabilizer and a thickener in large quantities and have excellent puncture property. The microneedle is used to administer a drug transdermally and comprises a top section, a shaft section and a base section, wherein (i) the tip apex angle (±) is 15 to 60°; (ii) the tip diameter (D 0 ) is 1 to 20 µm; (iii) the area (A 3 ) of the top surface of the base section is larger than the area (A 2 ) of the bottom surface of the shaft section; (iv) the following expressions (1) and (2) are satisfied H / D 4 ‰§ 3 (H is the overall height, and D 4 is the diameter of the bottom surface of the base section) ² ‰§ 90 - 0.5 �¢ ± (² is the angle formed between the side surface of the shaft section and the top surface of the base section, and ± is the tip apex angle.); and (v) a solid composition containing a drug is fixed to the side surface of the shaft section and the following expression (5) is satisfied. 10 �¢ ° ‰¦ ³ ‰¦ 60 �¢ ° (³ is the angle formed by tangent lines connecting the apex of the top section and the surface of the solid composition fixed to the side surface of the shaft section.)

    ADHESIVE PATCHING AID FOR MICRONEEDLE ADHESIVE SKIN PATCH
    13.
    发明公开
    ADHESIVE PATCHING AID FOR MICRONEEDLE ADHESIVE SKIN PATCH 审中-公开
    HEFTPFLASTERUNTERSTÜTZUNGFÜREIN DURCH MIKRONADELN HAFTENDES HEFTPFLASTER

    公开(公告)号：EP2526995A4

    公开(公告)日：2013-07-03

    申请号：EP11734514

    申请日：2011-01-20

    申请人： MEDRX CO LTD

    发明人： KOBAYASHI KATSUNORI ,  HAMAMOTO HIDETOSHI

    IPC分类号： A61M37/00

    CPC分类号： A61M37/0015 ,  A61M2025/0253 ,  A61M2037/0023 ,  A61M2037/0046 ,  A61M2037/0061

    摘要： Provided is an applicator that holds a microneedle to facilitate puncture of the skin, and enables close adhesion, with an adhesive sheet such as a tape and the like, of the microneedle puncturing the skin, even without touching with the hand. In the present invention, it was found that puncture of the skin with a microneedle is facilitated and the microneedle can be fixed to the skin in close adhesion, by using an ingot-shape assisting tool as a table to hold a microneedle, and placing an adhesive sheet such as a tape and the like on the side face of the assisting tool. As a result of the above, practicalization of a microneedle patch, which is easily portable and enables convenient drug administration to the skin, has been enabled.

    摘要翻译： 提供一种用于保持微针以促进皮肤穿刺的施用器，并且即使不用手触摸，也能够将微针的诸如胶带等的粘合片紧密地刺入皮肤。 在本发明中，发现用微针穿刺皮肤是容易的，并且通过使用锭状辅助工具作为工作台来保持微针，并且将微针固定在皮肤上，并且将微针固定在皮肤上 粘合片如胶带等在辅助工具的侧面上。 作为上述的结果，已经实现了易于携带并且能够方便地向皮肤施用药物的微针贴片的实现。

    PROCESS FOR PRODUCING PAD BASE FOR TRANSDERMAL DRUG ADMINISTRATION, PAD BASE FOR TRANSDERMAL DRUG ADMINISTRATION AND NEEDLE
    15.
    发明公开
    PROCESS FOR PRODUCING PAD BASE FOR TRANSDERMAL DRUG ADMINISTRATION, PAD BASE FOR TRANSDERMAL DRUG ADMINISTRATION AND NEEDLE 审中-公开
    一种用于生产支持基地透皮药品监督管理局，PAD基地透皮药物管理局，针

    公开(公告)号：EP1632263A4

    公开(公告)日：2008-04-30

    申请号：EP04736595

    申请日：2004-06-10

    申请人： MEDRX CO LTD

    发明人： MAENOSONO SHINYA ,  SUZUKI YASUSHI ,  AKITOMO HIROSHI ,  HAMAMOTO HIDETOSHI ,  ISHIBASHI MASAKI

    IPC分类号： A61M37/00

    CPC分类号： A61M37/0015 ,  A61M2037/003 ,  A61M2037/0038 ,  A61M2037/0053

    摘要： In the conventional micropatch method, the skin is pricked with solid needles, and vibration is applied by means of a vibrator so as to increase the needle-skin interstice to thereby accomplish drug administration. In the invention, there are provided a pad base for transdermal drug administration whereby transdermal administration of a medicinal drug can be accomplished without need to apply vibration, and provided a process wherein the pad base can easily be produced. One end of each of metal thin wires is immersed in the vertical direction in a synthetic resin raw material solution so as to cause the synthetic resin raw material solution to adhere to the circumference of the metal thin wires. The synthetic resin raw material solution is hardened, and thereafter the metal thin wires are pulled out. Thus, there can be obtained a structure comprising adherent substrate (2) and, disposed erect on the skin side surface thereof, microneedles (1) being tubular and having bell-bottom outer wall. Medicinal drug charged in the hollow portion (3) of microneedles (1) can be injected in the skin, thereby effecting transdermal drug administration. Further, the microneedles (1) are resistant to breaking off because of the bell-bottom shaping.