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公开(公告)号：EP3463508A1
公开(公告)日：2019-04-10
申请号：EP17728031.0
申请日：2017-05-26
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公开(公告)号：EP3436196A2
公开(公告)日：2019-02-06
申请号：EP17717028.9
申请日：2017-03-27
IPC分类号： B01L3/00 , G01N33/569
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公开(公告)号：EP3254008B1
公开(公告)日：2018-12-26
申请号：EP16708248.6
申请日：2016-02-04
IPC分类号： F16K99/00
CPC分类号： B01L3/502738 , B01L2200/027 , B01L2300/0816 , B01L2300/12 , B01L2300/123 , B01L2300/14 , B01L2400/0638 , B01L2400/082 , C12M21/08 , C12M23/16 , F16K7/126 , F16K99/0015 , F16K2099/008
摘要： Systems and methods disclosed herein related to an apparatus including a fluid flow plate and a microfluidic valve assembly. The fluid flow plate includes a plurality of polymer layers that define a fluid flow passage through the microfluidic valve assembly. The microfluidic valve assembly includes a valve seat, a flexible membrane, a valve cavity, a valve head, and an actuator. The actuator is configured to selectively control pressure applied by the valve head to the flexible membrane, such that in a first actuator state the valve head depresses the flexible membrane into the valve cavity and into contact with the valve seat, thereby preventing fluid flow through the valve assembly, and in a second state, the valve head and the flexible membrane are retracted substantially out of the valve cavity allowing fluid to flow through the valve assembly. In various implementations, the valve seat and/or the flexible membrane include an elastomer layer.
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公开(公告)号：EP3411115A1
公开(公告)日：2018-12-12
申请号：EP17704625.7
申请日：2017-01-30
发明人： BERNSTEIN, Jonathan , FREEMAN, Daniel , IRION, Reed , INGERSOLL, Brett , DUWEL, Amy , CZARNECKI, Andrew , DANIELS, Brian , ACHYUTA, Anilkumar Harapanahalli , MCLAUGHLIN, Bryan
摘要： This disclosure provides systems and methods for delivering a neural stimulation pulse. A neural implant device can include an energy harvesting circuit configured to receive an input signal and generate an electrical signal based on the received input signal. A diode rectifier in series with the energy harvesting circuit can rectify the electrical signal. The energy harvesting circuit and the diode rectifier can be encapsulated within a biocompatible electrically insulating material. A neural electrode can be exposed through the biocompatible electrically insulating material. The neural electrode can be configured to deliver a neural stimulation pulse. The neural implant device can have a volume that is less than about 1.0 cubic millimeter.
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公开(公告)号：EP3192369B1
公开(公告)日：2018-12-12
申请号：EP16202467.3
申请日：2008-04-14
IPC分类号： A01N1/00
CPC分类号： A61F2/06 , A61F2/022 , A61F2/04 , A61F2/062 , A61F2002/068 , G01N33/5008 , G06F19/00
摘要： The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b) - (e). The invention also provides compositions comprising a vascular layer for use in tissue lamina as well as a medical devices having a vascular layer and kits.
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公开(公告)号：EP3177708B1
公开(公告)日：2018-07-25
申请号：EP15757598.6
申请日：2015-08-05
CPC分类号： C12M27/00 , C12M21/08 , C12M23/12 , C12M27/18 , C12M29/10 , C12M29/12 , C12M29/18 , C12M41/44 , C12M41/48
摘要： Fluid circulation and leveling systems and methods of using the same are described. A fluid circulation system includes a fluid mixing chamber and open fluid chambers in fluid communication with the fluid mixing chamber. Each open fluid chamber includes a microfluidic fluid leveling conduit with an orifice disposed in the open fluid chamber at a minimum fluid level associated with a corresponding minimum fluid volume. A controller causes a first pump to generate a first direction of fluid flow during a first time period between the open fluid chambers, and causes the first pump to generate a second direction of fluid flow during a second time period between the first and second open fluid chambers. The controller also causes a second pump to generate a flow of fluid during a third time period from one of the first and second open fluid chambers into the fluid mixing chamber.
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公开(公告)号：EP3304234A1
公开(公告)日：2018-04-11
申请号：EP16803905.5
申请日：2016-04-27
IPC分类号： G05D1/08
CPC分类号： B64G1/286 , B64G1/242 , B64G1/283 , B64G2001/245 , G05D1/0883
摘要： A new approach for rapid slew and settle of small satellites is based on four single degree-of-freedom control moment gyroscopes with variable speed flywheels (or reaction wheels) in a pyramid configuration, combined with path and endpoint constraint time-optimal control. The path and endpoint constrained time-optimal control can be augmented with momentum management without the use of additional actuators.
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公开(公告)号：EP3013691B1
公开(公告)日：2018-03-07
申请号：EP14817171.3
申请日：2014-05-16
发明人： LAINE, Juha-Pekka , BLASCHE, Gregory, P. , CHAPARALA, Murali, V. , DAWSON, Robin , LANE, Benjamin , SMITH, Stephen, P. , WALDRON, Erik
CPC分类号： G01S3/7867 , G01B9/06 , G01B2290/10 , G01C21/025 , G01S3/785 , G02B6/0288 , G02B6/122 , G02B6/124 , G02B6/262 , G02B6/34 , G02B6/3548 , G02B2006/12147
摘要： A chip scale star tracker that captures plane-wave starlight propagating in free space with a wafer-thin angle-sensitive broadband filter-aperture, and directs the light into a waveguide structure for readout. Angular information about the star source is determined from characteristics of the starlight propagating in the waveguide. Certain examples include internal propagation-constant-based baffling to elimination stray light from extreme angles.
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公开(公告)号：EP2721141B1
公开(公告)日：2018-02-07
申请号：EP12732900.1
申请日：2012-06-15
IPC分类号： C12M3/00
摘要： Devices and methods are disclosed herein for a biomimetic flow apparatus. The biomimetic flow apparatus includes a microfluidic flow channel and an inlet in fluid connection with the flow channel for allowing fluid to flow into the flow channel. The flow channel has at least one surface with a topography formed therein. The topography of the at least one surface of the flow channel is selected to cause cells in a cell layer above the surface to achieve an arrangement, behavior, or morphology. The cell arrangement, behavior, or morphology is determined at least in part by the topography of the at least one surface.
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公开(公告)号：EP3230679A1
公开(公告)日：2017-10-18
申请号：EP15801295.5
申请日：2015-11-06
发明人： LAINE, Juha-Pekka , BLASCHE, Gregory , DAWSON, Robin , MCCLAIN, Sean , SMITH, Stephen P. , LARSEN, Robert , ARANT, Charles , OSTROWSKI, William
CPC分类号： F41G3/145 , G01S7/4815 , G01S17/66 , G01S17/89
摘要： A device and method for selectively illuminating and designating multiple targets in the air or on the ground simultaneously. The device comprises a light source, a switching array and a ball lens. Light from the light source is routed through the switching array, which can addressably output multiple light beams simultaneously. The light beams from the switching array illuminate the backside of a low F-number ball lens. The ball lens creates highly collimated output beams independently (and simultaneously) from any of the output source points of the switching array. These output beams can be used to simultaneously designate multiple targets. When the target illuminating device includes an optional detector array, light scattered from targets can be refracted by the balls lens to impinge on the detector array. Signals from the detector array representing the received light beams can be used for target imaging.
摘要翻译： 一种装置和方法，用于同时选择性地照亮和指定空中或地面上的多个目标。 该装置包括光源，开关阵列和球透镜。 来自光源的光线通过开关阵列，可以同时输出多个光束。 来自开关阵列的光束照射低F数球透镜的背面。 球透镜独立（同时）从开关阵列的任何输出源点创建高度准直的输出光束。 这些输出光束可以用来同时指定多个目标。 当目标照明装置包括可选的探测器阵列时，从目标散射的光线可被球透镜折射以撞击探测器阵列。 来自表示接收到的光束的来自检测器阵列的信号可以用于目标成像。
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