公开(公告)号：EP2849657A1

公开(公告)日：2015-03-25

申请号：EP13790201.1

申请日：2013-05-13

申请人： Pulse Therapeutics, Inc.

发明人： CREIGHTON, Francis, M. ,  SABO, Michael ,  NULL, Christopher ,  EPPLIN, Gerard ,  WACHTMAN, James Christopher

IPC分类号： A61B17/22 ,  A61N2/10 ,  A61M5/142 ,  A61B8/00

CPC分类号： A61B17/3207 ,  A61B17/320758 ,  A61B34/25 ,  A61B34/30 ,  A61B34/73 ,  A61B2017/00345 ,  A61B2017/00411 ,  A61B2017/22082 ,  A61B2017/320004 ,  A61N2/004 ,  A61N2/12

摘要： Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one embodiment, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Magnetic nanoparticles are provided having a non-specialized chemical coating facilitating association with a chemical composition by a user before infusion. Systems are provided for delivering a consistent infusion mass of magnetic nanoparticles to a patient.

摘要翻译： 一些实施例提供一种用于使用远程放置的产生磁场的定子在脉管系统中外部操纵磁性纳米颗粒的系统。 在一个实施例中，系统和方法涉及使用基于永磁体或电磁场产生定子源的流体介质中的磁性纳米颗粒的控制。 这种系统可用于增加治疗剂在诸如人类循环系统的流体介质中的扩散，其可导致循环系统中的流体阻塞物（例如血管闭塞）的实质性清除，导致血流量增加。 提供了具有非专门化学涂层的磁性纳米颗粒，其有助于使用者在输注之前与化学成分相关联。 系统被提供用于将一致的输注质量的磁性纳米颗粒递送给患者。

公开(公告)号：EP2542304A4

公开(公告)日：2014-07-30

申请号：EP11751199

申请日：2011-03-01

申请人： VIBRANT MED EL HEARING TECH

发明人： BALL GEOFFREY R ,  HAMMERER DOMINIK

IPC分类号： A61N2/10 ,  A61B17/12 ,  A61B17/122 ,  A61N2/06

CPC分类号： A61F5/0079 ,  A61F2/0036

公开(公告)号：EP2490764A4

公开(公告)日：2013-04-10

申请号：EP10825609

申请日：2010-10-20

申请人： WOLFE THOMAS J

发明人： WOLFE THOMAS J

IPC分类号： A61N2/10 ,  A61B17/20 ,  A61M25/00

CPC分类号： A61N1/40 ,  A61B17/22 ,  A61B2017/00876 ,  A61B2017/22038 ,  A61B2017/22042 ,  A61B2017/22079 ,  A61B2017/22082 ,  A61M25/00 ,  A61M25/0054 ,  A61M25/0082 ,  A61M25/0108 ,  A61M25/0158 ,  A61M25/09 ,  A61M2025/0008 ,  A61M2025/09133 ,  A61M2025/09183 ,  A61N2/02

公开(公告)号：EP1166291A4

公开(公告)日：2002-09-11

申请号：EP00907340

申请日：2000-03-03

申请人： PARAGON MEDICAL LTD

发明人： GRAY BRUCE NATHANIEL ,  JONES STEPHEN KEITH ,  CAMMARANO RAFFAELE

IPC分类号： A61K33/24 ,  A61K41/00 ,  A61N1/40 ,  A61N2/10 ,  H05B6/10 ,  H01F1/11 ,  A61K33/26 ,  A61N2/02 ,  A61N2/04 ,  H01F1/113

CPC分类号： A61N1/406 ,  A61K33/24 ,  A61K41/0052

摘要： A magnetic material having a magnetic heating efficiency of at least 4.5x10-8 J.m/A.g in a cyclic magnetic field where the product of the amplitude and frequency of the applied field is less than or equal to 5x108 A/m.s, and the frequency of the applied filed is at least 20 kHz. The ideal magnetic material is characterized by a perfectly rectangular hysteresis loop, i.e. loop squareness of 1, with coercivity of 25 kA/m or less and high saturation magnetization. Preferably the magnetic material has a predominately cubic magnetic crystalline anisotropy. Preferably the magnetic material is a substituted magnetite (Fe3O4) or gamma-ferric oxide (gammaFe2O3) crystalline lattice in which some of the iron atoms in that crystalline lattice have been substituted for one or more alternate metals atoms. Desirably, the metal atom is a member of the group: cobalt, zinc, nickel, manganese, magnesium, copper, chromium, gallium, cadmium.

公开(公告)号：EP1076585A1

公开(公告)日：2001-02-21

申请号：EP99905780.5

申请日：1999-02-05

申请人： Light Sciences Limited Partnership

发明人： CHEN, James, C. ,  BROWN, David, J. ,  HUSTON, Darrin ,  WILKERSON, Brian, D.

IPC分类号： A61N2/12 ,  A61N2/00 ,  A61N2/06 ,  A61N2/10

CPC分类号： A61N1/3787 ,  A61F2250/0001 ,  A61N1/08

摘要： An external power head (20) is energized by a motor (22) causing movement of an element (26) that produces a varying magnetic field, thereby inducing power in an implanted receiver coil (30) within a patient's body. The external power head (20) includes either one or more moving permanent magnets (42), or one or more moving elements that vary the magnetic flux coupled to the implanted receiver coil (30). As a result of the varying magnetic field experienced by the implanted receiver coil (30), an electric current flows from the implanted receiver coil (30) to energize an implanted medical device (34).

公开(公告)号：EP0551453B1

公开(公告)日：1995-01-18

申请号：EP92911425.4

申请日：1992-04-27

申请人： BAXTER INTERNATIONAL INC.

发明人： GRIMM, Daniel J. ,  LEUENBERGER, Mark S.

IPC分类号： A61L2/12 ,  A61N2/10 ,  H01J37/20 ,  A61J1/00 ,  A61M1/36

CPC分类号： A61L2/10 ,  A61J1/10 ,  A61J1/1406 ,  A61J1/1462 ,  A61J1/1468 ,  A61J1/1487 ,  A61J2205/10 ,  A61J2205/20 ,  A61J2205/30 ,  A61L2/0011 ,  Y10T436/12

摘要： A container (10) for irradiation comprises a flexible, flat collapsible wall (12, 13) defining a sealed chamber (36), the plastic material of the wall (12, 13) is substantially transparent to irradiation, typically ultraviolet radiation. Access ports (22, 24, 26) are provided for communicating through the wall (12, 13) to the chamber (36). A flap (32) is provided, integral with the wall (12, 13) and spaced from the chamber (36), and carries identifying indicia (38) including a typical bar code indicia (40), so that the wall (12, 13) may be at least substantially free of opaque indicia. Also, structure may be provided for detecting and indicating exposure of the container to irradiation, such as ultraviolet sensitive tape (50) adhering to the flap (32). Alignment holes (46) may be provided, typically in the flap (32), to facilitate orientation of the container (10) with apparatus for irradiation (51) and apparatus for bar code reading (72), making use of alignment pins (70) carried by such apparatus (51).

公开(公告)号：EP0141915A1

公开(公告)日：1985-05-22

申请号：EP84109186.1

申请日：1984-08-02

申请人： Dekleva, Nikola, Ph.D., M.D. ,  Majic, Vidan, Ph.D., Dipl.-Ing. ,  Belesnin, Bogdan, Prof., Ph.D., M.D. ,  Antic, Radoslav, Dipl.-Ing.

发明人： Dekleva, Nikola, Ph.D., M.D. ,  Majic, Vidan, Ph.D., Dipl.-Ing. ,  Belesnin, Bogdan, Prof., Ph.D., M.D. ,  Antic, Radoslav, Dipl.-Ing.

IPC分类号： A61N2/10

CPC分类号： A61N2/06

摘要： A magnetotherapeutic plug enables the treatment of rectal and vaginal inflammations especially haemorrhoids, by direct action on said tissue, and comprises magnetic elements (N S).
The plug is adapted to the anatomic shape of rectal and vaginal cavities, so that it provides reliable contact with the tissue, without sharp edges that could damage the tissue during use, so that it is applied easily and simply and remains in place without falling out during treatment.
The magnetic flux density does not exceed 80 mT, preferably being from 20 mTto 40 mT.

摘要翻译： 磁疗塞可以通过对所述组织的直接作用来治疗直肠和阴道炎症，特别是痔疮，并且包括磁性元件（N S）。 该插头适应于直肠和阴道腔的解剖形状，使得其提供与组织的可靠接触，而没有在使用期间可能损伤组织的尖锐边缘，使得其容易且简单地应用并保持在适当位置而不会掉落 在治疗期间。 磁通密度不超过80mT，优选为20mT至40mT。

公开(公告)号：EP3566740B1

公开(公告)日：2024-08-14

申请号：EP19176952.0

申请日：2014-03-14

IPC分类号： A61M25/088 ,  A61N2/06 ,  A61N2/10 ,  A61B17/11 ,  A61M1/36 ,  A61B34/00 ,  A61B18/14 ,  A61B17/12

CPC分类号： A61B17/11 ,  A61B17/1204 ,  A61B17/12136 ,  A61B18/1492 ,  A61M25/0127 ,  A61B2017/0087620130101 ,  A61B2017/110720130101 ,  A61B2017/113920130101 ,  A61B2017/2207120130101 ,  A61B34/73 ,  A61B18/1477 ,  A61B2018/0057720130101 ,  A61B2018/0060120130101 ,  A61B2018/142520130101 ,  A61M1/3655

公开(公告)号：EP3436141A1

公开(公告)日：2019-02-06

申请号：EP17776368.7

申请日：2017-03-27

申请人： Med-El Elektromedizinische Geraete GmbH

发明人： DHANASINGH, Anandhan ,  JOLLY, Claude ,  ZIMMERLING, Martin

IPC分类号： A61N1/375 ,  A61F11/04 ,  A61N1/05 ,  A61N1/372 ,  A61N2/10

摘要： An implantable medical device includes an implantable coil case that contains a communications coil. A magnet receptacle is located within the coil case at the radial center and has a magnet opening in one of the lateral surface or the medial surface of the coil case. A magnet fitting groove is recessed into one of the lateral or medial surface of the coil case and extends from the magnet opening to the outer circumference of the coil case. A u-shaped implant magnet clip has parallel clip legs that are connected at a closed end of the u-shape, and an implant magnet is attached to one of the clip legs. The coil case and the magnet clip are configured to cooperate for a portion of the coil case to fit between the clip legs and the implant magnet to slide through the magnet fitting groove and fit through the magnet opening into the magnet receptacle.

公开(公告)号：EP3060297A1

公开(公告)日：2016-08-31

申请号：EP14855699.6

申请日：2014-10-24

申请人： MED-EL Elektromedizinische Geräte GmbH

发明人： HORNSTEINER, Christoph

IPC分类号： A61N2/10 ,  A61N2/08 ,  A61N2/06

CPC分类号： A61B5/062 ,  A61B5/05 ,  A61B5/1075 ,  A61B5/7278 ,  A61B2562/0223 ,  A61B2562/046 ,  G01B7/10 ,  G01B7/14 ,  G01R33/0094

摘要： A method is described for estimating skin thickness over an implanted magnet. A plane is defined that is perpendicular to the skin of a patient over an implanted magnet and characterized by x- and y-axis coordinates. The magnetic field strength of the implanted magnet is measured using an array of magnetic sensors on the skin of the patient. From the measured magnetic field strength, at least one x-axis coordinate in the plane is determined for at least one y-axis zero position on the array where a y-axis component of the measured magnetic field strength is zero. From that, a y-axis coordinate of the at least one y-axis zero is calculated as a function of the at least one x-axis coordinate, such that the y-axis coordinate represents thickness of the skin over the implanted magnet.

摘要翻译： 描述了用于估计植入磁体上的皮肤厚度的方法。 定义了一个平面，其垂直于植入磁体上的患者皮肤，并以x轴和y轴坐标为特征。 使用在患者皮肤上的磁性传感器阵列来测量植入的磁体的磁场强度。 根据测量的磁场强度，对于测量的磁场强度的y轴分量为零的阵列上的至少一个y轴零位置，确定平面中的至少一个x轴坐标。 由此，至少一个y轴零点的y轴坐标被计算为至少一个x轴坐标的函数，使得y轴坐标表示植入磁体上皮肤的厚度。