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768 条记录 (耗时 0.034 秒)

    METHOD FOR OBTAINING TUMOR PEPTIDES AND USES THEREOF
    21.
    发明公开
    METHOD FOR OBTAINING TUMOR PEPTIDES AND USES THEREOF 审中-公开

    公开(公告)号：EP3373960A1

    公开(公告)日：2018-09-19

    申请号：EP16798675.1

    申请日：2016-11-11

    申请人： IEO - Istituto Europeo di Oncologia Srl

    发明人： PENNA, Giuseppe ,  RESCIGNO, Maria

    IPC分类号： A61K39/00

    CPC分类号： A61K39/0011 ,  A61K2039/5154

    摘要： The present invention refers to a method for obtaining a cell culture supernatant or a fraction thereof comprising a specific tumor antigen peptide repertoire comprising the steps of: a) exposing in suitable conditions a tumor cell culture expressing said specific tumor antigen peptide repertoire to at least one Pattern Recognition Receptor (PRR) agonist and/or to one inflammatory cytokine to increase the opening of connexin–hemichannels (CxH); b) collecting the cell culture supernatant; and c) optionally obtaining a fraction of said supernatant, wherein said supernatant comprises MHC class I and MHC class II peptides and non-classical MHC molecules (HLA-E).

    APPARATUS FOR AUTOMATICALLY TREATING EXCREMENT AND CONTROLLING METHOD THEREOF
    25.
    发明授权
    APPARATUS FOR AUTOMATICALLY TREATING EXCREMENT AND CONTROLLING METHOD THEREOF 有权

    公开(公告)号：EP2556813B1

    公开(公告)日：2018-06-13

    申请号：EP11766148.8

    申请日：2011-04-06

    申请人： Curaco, Inc.

    发明人： LEE, Jong Chan ,  LEE, Ho Sang

    IPC分类号： A61G9/00 ,  A61F5/44 ,  A61F5/451

    CPC分类号： A61G9/003 ,  A61F5/451 ,  A61G9/006

    摘要： The present invention relates to an apparatus for automatically treating excrement which can supply warm washing water from the initial cleansing operation in a bidet and a control method thereof. The apparatus for automatically treating the excrement according to the present invention comprises: a mounting unit (1) for receiving excrement of a patient; a control unit (2) having a washing water supply part (50) for supplying the washing water for washing the excrement and the bidet to the mounting unit (1); and a washing water supply path which is connected from the washing water supply part (50) to the mounting unit (1). The washing water supply part (50) comprises: a washing water storage tank (51) in which the washing water is stored; a pump (52) which is operated in a forward direction to supply the washing water of the washing water storage tank (51) to the mounting unit (1) or which is operated in a reverse direction to collect the residual washing water in the washing water supply path to the washing water storage tank (51); an instantaneous water heater (53) provided on the washing water supply path to heat the washing water to be supplied to the mounting unit (1); and a control portion which controls the operations of the pump (52) to be operated in the forward direction or the reverse direction, the control portion instantly controlling the operation of the pump (52) to be operated in the forward direction when excrement is sensed in the mounting unit (1), and the control portion controlling the operation for collecting the residual washing water within the washing water supply path before the instantaneous water heater (53) by operating the pump in the reverse direction during a preset period after the operation for processing the excrement is finished.

    AUTOMATIC APPARATUS AND METHOD FOR CULTURES OF ORGANISMS IN AN AQUATIC ENVIRONMENT
    27.
    发明公开
    AUTOMATIC APPARATUS AND METHOD FOR CULTURES OF ORGANISMS IN AN AQUATIC ENVIRONMENT 审中-公开
    在水生环境中用于有机体培养的自动装置和方法

    公开(公告)号：EP3282834A1

    公开(公告)日：2018-02-21

    申请号：EP16726161.9

    申请日：2016-04-14

    申请人： Stazione Zoologica "Anton Dohrn"

    发明人： ZUPO, Valerio ,  MUTALIPASSI, Mirko

    IPC分类号： A01K61/00 ,  A01K63/04 ,  A01K63/00

    CPC分类号： A01K63/04 ,  A01K61/10

    摘要： An apparatus (1) for growing at least one culture of organisms in a aquatic environment, comprising at least one storage tank (10) for continuously collecting not treated water, at least one filtering tank (20, 20'), connected to the storage tank (10) and suitable for receiving water from the storage tank (10) for the treatment thereof in order to obtain a culture medium, at least one rearing tank (30, 30', 30'',30'''), connected to the filtering tank (20, 20') and suitable for receiving the treated water from the filtering tank (20, 20') and comprising at least one container (32) for rearing the culture and at least one control and management system (70) for controlling the environmental conditions of growth of the culture and automatically varying the culture medium in response to variations in growth.