公开(公告)号：EP1492409A2

公开(公告)日：2005-01-05

申请号：EP03709683.1

申请日：2003-04-01

申请人： CHR. HANSEN A/S

发明人： FLAMBARD, Bénédicte

IPC分类号： A23C9/12 ,  C12N1/20 ,  A61K38/00 ,  C07K4/00

CPC分类号： A23C9/1234 ,  A23J3/10 ,  A23L33/18 ,  A23V2002/00 ,  A23V2200/00 ,  A23Y2220/39 ,  A23Y2240/41 ,  A61K38/00 ,  A23V2200/326 ,  A23V2250/55

摘要： A process for preparing peptides with anti-hypertensive properties and a process for preparing a functional food product comprising peptides with anti-hypertensive properties.

公开(公告)号：EP0626176B1

公开(公告)日：1999-11-17

申请号：EP93114403.4

申请日：1993-09-08

申请人： ABBOTT LABORATORIES

发明人： Cope, Frederick Oliver ,  Dewille, Normanella Torres ,  Richards, Ernest William ,  Abbruzzese, Bonnie Chandler ,  Parlet, Nickki Lynn ,  Mazer, Terrence Bruce ,  Snowden, Gregory Allan ,  Pease, Laura Ann

IPC分类号： A61K38/01 ,  A23L1/305 ,  A23L1/308 ,  A23L1/053 ,  A23L1/303 ,  A23J1/14

CPC分类号： A61K38/01 ,  A23J3/14 ,  A23J3/346 ,  A23L33/12 ,  A23L33/18 ,  A23L33/185 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00 ,  A61K38/168 ,  A61K38/17 ,  A61K2300/00 ,  A23V2200/30 ,  A23V2250/022 ,  A23V2250/55 ,  A23V2300/34

公开(公告)号：EP0448644B1

公开(公告)日：1996-03-27

申请号：EP90901465.6

申请日：1989-12-15

申请人： RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

发明人： CHIEN, Yie, W. ,  CHIEN, Te-Yen

IPC分类号： A61L15/16 ,  A61F13/02

CPC分类号： A23J3/32 ,  A23G1/56 ,  A23G3/346 ,  A23J3/341 ,  A23J3/346 ,  A23K20/147 ,  A23K50/30 ,  A23V2002/00 ,  A61F13/023 ,  A61F13/0253 ,  A61F2013/00544 ,  A61F2013/00906 ,  A61F2013/00927 ,  A61K9/7061 ,  A61K9/7069 ,  A61K9/7092 ,  A61K31/565 ,  A61K31/567 ,  A61K38/011 ,  A61K38/012 ,  A23G2200/02 ,  A23V2200/30 ,  A23V2250/55 ,  A23V2300/30

摘要： Transdermal estrogen/progestin absorption dosage units have been developed which comprise a backing layer, an adjoining polymer layer is an adhesive layer in which at least minimum effective dose of an estrogen is dissolved or microdispersed. Adhered to the polymer layer is an adhesive layer in which is dissolved and/or microdispersed at least minimum doses of progestin. Presently preferred is use of the natural estrogen, 17-beta-estradiol, or ethinyl estradiol or combinations thereof and of the progestin. The units have biologically acceptable adhesive and polymer layers. The adhesive layer can have dispersed one or more skin permeation enhancing agents. A separating layer can optionally be used in making the dosage units, which separate the adhesive and polymer layers, which permits estrogen transmission from the polymer layer during treatment. Dosage units are provided which transdermally deliver at least minimum daily doses of the estrogen and progestin for multiple days, such as for one week. The invention also provides a process of fertility control and estrogen replacement therapy using the novel dosage units. Also, the invention provides a fertility control system for fertility control using the novel dosage units.

公开(公告)号：EP0420979A1

公开(公告)日：1991-04-10

申请号：EP89902067.1

申请日：1989-02-02

申请人： HANKYU-KYOEI BUSSAN CO., LTD.

发明人： KAGAWA, Kyoichi ,  KANEDA, Takaya ,  TADOKORO, Tetsuo ,  MATSUMURA, Yoshikazu, Ueda Chemical Ind.Co.Ltd.

IPC分类号： A61K37/18

CPC分类号： A23G1/56 ,  A23G3/346 ,  A23G2200/02 ,  A23J3/32 ,  A23J3/341 ,  A23J3/346 ,  A23K20/147 ,  A23K50/30 ,  A23V2002/00 ,  A61K38/011 ,  A61K38/012 ,  A23V2200/30 ,  A23V2250/55 ,  A23V2300/30

摘要： A lipid metabolism improving agent for human beings or animals and a method of its use are disclosed. Conventional lipid metabolism improving agents require a large amount of intake or unavoidably cause side effects on the human body and there have been no agents which are effective not only as lipid metabolism improving agents but also for depression of in increase of bodily fat accompanying growth acceleration of livestock animals and aquatic animals and improvement of accumulated fat. This agent contains as the active ingredient low-molecular peptides of 3 to 4 in average amino acid chain length produced by hydrolysis of a protein or a protein-containing substance. This agent is administered in an amount as small as 0.1 to 50% based on lipid intake, thus improving lipid metabolism effectively without side effects.

摘要翻译： 公开了一种用于人或动物的脂质代谢改善剂及其使用方法。 常规的脂质代谢改善剂需要大量的摄取或不可避免地对人体产生副作用，并且没有任何有效的药剂不仅可以作为脂质代谢改善剂而且对于伴随生长加速的身体脂肪增加的抑制也是有效的 的牲畜和水生动物，并增加积累的脂肪。 该试剂含有作为活性成分的蛋白质或含蛋白质物质的水解产生的平均氨基酸长度为3〜4的低分子肽。 该药物的施用量基于脂质摄取量少至0.1至50％，从而有效改善脂质代谢而无副作用。

公开(公告)号：EP3373749A1

公开(公告)日：2018-09-19

申请号：EP16791172.6

申请日：2016-10-19

申请人： MJN U.S. Holdings LLC

发明人： GONZALEZ, Juan M. ,  LAMBERS, Teartse Tim. ,  VAN TOL, Eric A.F.

IPC分类号： A23L33/10 ,  A23L33/12 ,  A23L33/135 ,  A23L33/18 ,  A23L33/19 ,  A23L33/21 ,  A61P37/00

CPC分类号： A23L33/10 ,  A23L33/12 ,  A23L33/135 ,  A23L33/18 ,  A23L33/19 ,  A23L33/21 ,  A23V2002/00 ,  A23Y2220/00 ,  A23V2200/30 ,  A23V2200/304 ,  A23V2200/32 ,  A23V2200/3202 ,  A23V2200/3204 ,  A23V2250/00 ,  A23V2250/1884 ,  A23V2250/284 ,  A23V2250/5116 ,  A23V2250/54246 ,  A23V2250/55 ,  A23Y2220/73

摘要： Provided are nutritional compositions containing dietary butyrate. The nutritional compositions may exhibit additive or synergistic beneticial health effects when consumed. Further provided are methods for improving the shelf-stability and/or organoleptic properties of nutritional compositions including dietary butyrate.

公开(公告)号：EP2863761B1

公开(公告)日：2018-06-27

申请号：EP13725886.9

申请日：2013-05-22

申请人： MJN U.S. Holdings LLC

发明人： TANBONLIONG, Gretchen

IPC分类号： A23L33/135 ,  A23L33/18 ,  A61K35/74 ,  A61P1/00 ,  A61K38/01

CPC分类号： A23L33/40 ,  A23L33/135 ,  A23L33/18 ,  A23V2002/00 ,  A23Y2220/73 ,  A61K35/747 ,  A61K38/01 ,  A23V2200/304 ,  A23V2200/3204 ,  A23V2250/0612 ,  A23V2250/0644 ,  A23V2250/156 ,  A23V2250/1882 ,  A23V2250/304 ,  A23V2250/55 ,  A23V2250/70

摘要： The present disclosure provides compositions and methods for dietary management of celiac disease and food allergy in a subject, such as a formula-fed infant, via enteral administration of an effective amount of at least one hydrolyzed protein and Lactobacillus rhamnosus GG (LGG). The inventive nutritional compositions may contain a hydrolyzed protein component, a lipid component, a carbohydrate component, a vitamin component, a mineral component, and a prebiotic component in addition to a probiotic component, which comprises an effective amount of LGG.

公开(公告)号：EP2908657B1

公开(公告)日：2018-02-21

申请号：EP13779581.1

申请日：2013-10-21

申请人： DSM IP Assets B.V.

发明人： JANSE, Arthur Maurits Christiaan ,  VEERMAN, Cecile ,  SMOLDERS, Gerardus Johannes Franciscus

IPC分类号： A23J3/34 ,  A23J1/12 ,  A23L33/18

CPC分类号： A23J3/346 ,  A23J1/125 ,  A23J3/14 ,  A23L33/18 ,  A23V2002/00 ,  C12P21/06 ,  C12Y304/11 ,  C12Y304/21 ,  C12Y304/22 ,  C12Y304/23 ,  C12Y304/24 ,  C12Y304/24028 ,  C12Y304/25 ,  A23V2250/548 ,  A23V2250/55

摘要： The present invention provides a rice bran hydrolysate which comprises of more than 90%, preferably of more than 95%, of (poly) peptides with a molecular weight (MW) of more than 500 Da and which has a DH (Degree of Hydrolysis) of at least 10%, preferably between 10 and 16%. According to another aspect of the invention a process to produce a rice bran hydrolysate is provided.

公开(公告)号：EP2643005B1

公开(公告)日：2017-03-01

申请号：EP11784694.9

申请日：2011-11-21

申请人： Nestec S.A.

发明人： SPRENGER, Norbert

IPC分类号： A61K31/702 ,  A61K31/7016 ,  A61K35/74 ,  A61K35/741 ,  A61K35/745 ,  A61K38/00 ,  A61K38/01 ,  A61K45/06 ,  A23L33/00 ,  A23L33/18 ,  A23L33/21 ,  C12N1/00 ,  A61P17/00 ,  A61P37/02

CPC分类号： A61K38/17 ,  A23L33/18 ,  A23L33/21 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/7016 ,  A61K31/702 ,  A61K35/74 ,  A61K35/745 ,  A61K38/01 ,  A61K45/06 ,  A61K2300/00 ,  A23V2200/318 ,  A23V2250/28 ,  A23V2250/55

摘要： The invention discloses a composition comprising at least one N-acetyl lactosamine, at least one sialylated oligosaccharide and at least one fucosylated oligosaccharide, and a hydrolysate comprising partially and/or extensively hydrolysed proteins, for use in the prevention and/or treatment of skin conditions and skin diseases. Preferably said composition is a starter infant formula. Said skin disease is in particular atopic dermatitis.

摘要翻译： 本发明公开了一种组合物，其包含至少一种N-乙酰乳糖胺，至少一种唾液酸化寡糖和至少一种岩藻糖基化寡糖，以及包含部分和/或广泛水解的蛋白质的水解产物，用于预防和/或治疗皮肤病症 和皮肤疾病。 优选地，所述组合物是起始婴儿配方。 所述皮肤病特别是特应性皮炎。

公开(公告)号：EP3046552A1

公开(公告)日：2016-07-27

申请号：EP14744782.5

申请日：2014-07-02

申请人： International Nutrition Research Company

发明人： VINCENT, Claude

IPC分类号： A61K31/155 ,  A61K31/366 ,  A61K31/7016 ,  A61K33/00 ,  A61P3/04 ,  A61K38/01 ,  A61K38/38 ,  A61K38/08 ,  A61K31/4415 ,  A61K33/06 ,  A61K35/20 ,  A61P3/00 ,  A23L33/00

CPC分类号： A61K35/20 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23L33/175 ,  A23L33/18 ,  A23L33/19 ,  A23V2002/00 ,  A61K9/0053 ,  A61K31/155 ,  A61K31/198 ,  A61K31/202 ,  A61K31/355 ,  A61K31/366 ,  A61K31/401 ,  A61K31/405 ,  A61K31/426 ,  A61K31/4375 ,  A61K31/4415 ,  A61K31/59 ,  A61K33/04 ,  A61K33/06 ,  A61K33/30 ,  A61K38/06 ,  A61K38/08 ,  A61K38/193 ,  A61K38/38 ,  A61K38/446 ,  A61K2300/00 ,  C12Y115/01001 ,  A23V2200/326 ,  A23V2200/328 ,  A23V2250/0604 ,  A23V2250/062 ,  A23V2250/0626 ,  A23V2250/0628 ,  A23V2250/065 ,  A23V2250/1578 ,  A23V2250/187 ,  A23V2250/1882 ,  A23V2250/5424 ,  A23V2250/54242 ,  A23V2250/55 ,  A23V2250/7052 ,  A23V2250/7056 ,  A23V2250/71 ,  A23V2250/712

摘要： The invention relates to a composition suitable for use as a health product, comprising a mixture of active ingredients made up of at least: - a lactoserum hydrolysate with a molecular weight comprised between 200 and 5000 daltons, - alpha-lactalbumin, - at least one AMPK, MAPK, PPAR and/or SIRT1 cycle regulator, - milk calcium. It is particularly useful as a medical nutrition product or orally administered drug, to prevent and/or combat various diseases.

摘要翻译： 乳清水解产物，200个5000道尔顿，α-乳清蛋白，至少一种AMPK，MAPK，PPAR和/或之间的分子量：适于用作医疗产品，包括由至少的活性成分的混合物的组合物 SIRT1周期调节，和牛奶中的钙。 该组合物是作为医疗营养产品或口服给药的药物是特别有用的，以预防和/或防治各种疾病。

公开(公告)号：EP2986160A1

公开(公告)日：2016-02-24

申请号：EP14714531.2

申请日：2014-03-11

申请人： MJN U.S. Holdings LLC

发明人： HONDMANN, Dirk, ,  VAN TOL, Eric A.F. ,  GROSS, Gabriele ,  SCHOEMAKER, Marieke H. ,  LAMBERS, Teartse Tim ,  ROMACHO, Tania ,  ELSEN, Manuela ,  ECKEL, Jürgen

IPC分类号： A23L33/17 ,  A61K38/01 ,  A23J3/34 ,  A61P3/04

CPC分类号： A61K38/018 ,  A23J3/344 ,  A23L33/18 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/202 ,  A61K45/06 ,  A23V2200/326 ,  A23V2200/332 ,  A23V2250/1862 ,  A23V2250/1868 ,  A23V2250/28 ,  A23V2250/54246 ,  A23V2250/55

摘要： The present disclosure provides a method for activating adiponectin by administering a composition comprising peptides selected from a casein hydrolysate. Such a composition may reduce risk of heart attack and help in maintaining healthy weight. Preferably, the hydrolysate consists of peptides with a molecular weight of more than 500 Da.