公开(公告)号：EP0527936A4

公开(公告)日：1993-07-28

申请号：EP91910470

申请日：1991-05-06

申请人： REGEN CORPORATION

发明人： STONE, KEVIN, R.

IPC分类号： A61F2/28 ,  A61F2/00 ,  A61F2/02 ,  A61F2/30 ,  A61F2/38 ,  A61F2/42 ,  A61F2/44 ,  A61L27/00 ,  A61L27/20 ,  A61L27/22 ,  A61L27/24 ,  A61L27/26 ,  A61L27/46 ,  A61L27/48 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58

CPC分类号： A61F2/442 ,  A61F2/28 ,  A61F2/30756 ,  A61F2/30907 ,  A61F2/3094 ,  A61F2/30965 ,  A61F2/38 ,  A61F2/3872 ,  A61F2002/30062 ,  A61F2002/30131 ,  A61F2002/30205 ,  A61F2002/3023 ,  A61F2002/30677 ,  A61F2002/30736 ,  A61F2002/30766 ,  A61F2002/3082 ,  A61F2002/30879 ,  A61F2002/30904 ,  A61F2002/30957 ,  A61F2002/4276 ,  A61F2002/4279 ,  A61F2002/4282 ,  A61F2002/4284 ,  A61F2002/4289 ,  A61F2002/4292 ,  A61F2002/4294 ,  A61F2002/4297 ,  A61F2210/0004 ,  A61F2230/0013 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2310/00365

摘要： A prosthetic intervertebral disc (200) is disclosed which can be implanted in the human skeleton, and which can act as a scaffold for regrowth of intervertebral disc material. The disc (200) includes a dry, porous, volume matrix of biocompatible and bioresorbable fibers which may be interspersed with glycosaminoglycan molecules. The matrix is adapted to have in vivo an outer surface contour substantially the same as that of a natural intervertebral disc, whereby said matrix establishes an at least partially bioresorbable scaffold adapted for ingrowth of intervertebral fibrochondrocytes. Cross-links may be provided by a portion of the GAG molecules.

公开(公告)号：EP2806831B1

公开(公告)日：2017-07-05

申请号：EP13741370.4

申请日：2013-01-21

申请人： Aptis Medical, LLC

发明人： SCHEKER, Luis, Roman

IPC分类号： A61F2/42

CPC分类号： A61F2/4241 ,  A61F2/4261 ,  A61F2002/30378 ,  A61F2002/30433 ,  A61F2002/305 ,  A61F2002/30578 ,  A61F2002/30649 ,  A61F2002/30878 ,  A61F2002/4258 ,  A61F2002/4276

公开(公告)号：EP2806831A4

公开(公告)日：2015-12-16

申请号：EP13741370

申请日：2013-01-21

申请人： APTIS MEDICAL LLC

发明人： SCHEKER LUIS ROMAN

IPC分类号： A61F2/42

CPC分类号： A61F2/4241 ,  A61F2/4261 ,  A61F2002/30378 ,  A61F2002/30433 ,  A61F2002/305 ,  A61F2002/30578 ,  A61F2002/30649 ,  A61F2002/30878 ,  A61F2002/4258 ,  A61F2002/4276

公开(公告)号：EP2916776A1

公开(公告)日：2015-09-16

申请号：EP13853306.2

申请日：2013-11-11

申请人： Solomons, Michael Wayne

发明人： Solomons, Michael Wayne

IPC分类号： A61F2/42

CPC分类号： A61F2/4261 ,  A61F2002/3052 ,  A61F2002/4276

摘要： A prosthesis (10) comprising a trapezium implant (12) and a mounting element (16) adapted to slidably attach the trapezium implant (12) to a flexor carpi radialis tendon (18) of the patient.

摘要翻译： 一种包括梯形植入物（12）和适于将梯形植入物（12）可滑动地附接到患者的桡侧腕屈肌腱（18）的安装元件（16）的假体（10）。

公开(公告)号：EP2385814A1

公开(公告)日：2011-11-16

申请号：EP10729391.2

申请日：2010-01-07

申请人： Gannoe, Jamy ,  Arellano, Luis

发明人： Gannoe, Jamy ,  Arellano, Luis

IPC分类号： A61F2/42

CPC分类号： A61B17/0401 ,  A61B17/8061 ,  A61B17/842 ,  A61B2017/0414 ,  A61B2017/044 ,  A61F2/4261 ,  A61F2/4606 ,  A61F2/4684 ,  A61F2002/30464 ,  A61F2002/30588 ,  A61F2002/30772 ,  A61F2002/3092 ,  A61F2002/4258 ,  A61F2002/4276

摘要： A carpometacarpal joint replacement system for replacing the trapezium bone in the hand is provided. The system includes a trapezial implant for the carpometacarpal joint resulting in replacement of the carpal trapezium bone with a prosthesis having the same anatomical configuration as the trapezium bone. The implant device comprises a plurality of concave surfaces, with the plurality of concave surfaces articulating with the carpal and metacarpal bones.

摘要翻译： 提供用于替换手中的梯形骨的腕掌关节置换系统。 该系统包括用于腕掌关节的梯形植入物，导致用具有与梯形骨相同的解剖结构的假体替代腕骨梯形骨。 植入装置包括多个凹表面，多个凹表面与腕骨和掌骨连接。

公开(公告)号：EP2309950A1

公开(公告)日：2011-04-20

申请号：EP09790284.5

申请日：2009-07-10

申请人： Integra LifeSciences Corporation

发明人： WEISS, Amold-peter, C. ,  PATEL, Jignesh, B. ,  VOHRA, Karishma ,  DESAI, Namrata ,  INGRAM, Ronald, T. ,  SPILKER, Mark ,  PRYOR, Timothy, J. ,  BEAM-BRENNAN, Heather

IPC分类号： A61F2/42 ,  A61F2/28 ,  A61F2/30

CPC分类号： A61F2/4261 ,  A61F2/3094 ,  A61F2002/2817 ,  A61F2002/30006 ,  A61F2002/30011 ,  A61F2002/30062 ,  A61F2002/30291 ,  A61F2002/30448 ,  A61F2002/30599 ,  A61F2002/30892 ,  A61F2002/30971 ,  A61F2002/4276 ,  A61F2210/0004 ,  A61F2220/005 ,  A61F2230/0091 ,  A61F2250/0015 ,  A61F2250/0023 ,  A61F2250/0063 ,  A61F2310/00365 ,  A61L27/24 ,  A61L27/58

摘要： Biocompatible, resorbable medical implants and related methods are disclosed in which the implant (10) can be made of a collagen matrix (20) for filling a space after partial or total resection of the trapezium bone of the wrist. The resorbable medical implant can include a plurality of surface projections (30), and the collagen matrix can be folded or spirally wound about itself to form a spiral roll.

公开(公告)号：EP1009335A1

公开(公告)日：2000-06-21

申请号：EP98918423.9

申请日：1998-04-17

申请人： W.L. GORE & ASSOCIATES, INC.

发明人： BERMAN, Andrew, B.

IPC分类号： A61F2/42 ,  A61L27/00

CPC分类号： A61B17/562 ,  A61F2/08 ,  A61F2/4261 ,  A61F2002/30034 ,  A61F2002/30062 ,  A61F2002/30293 ,  A61F2002/30299 ,  A61F2002/30301 ,  A61F2002/30563 ,  A61F2002/30754 ,  A61F2002/30878 ,  A61F2002/4248 ,  A61F2002/4258 ,  A61F2002/4276 ,  A61F2210/0004 ,  A61F2230/0091 ,  A61F2230/0093 ,  A61F2230/0095 ,  A61F2250/0031 ,  A61L27/58

摘要： A resorbable implant (41) for interposition arthroplasty which is intended to fill a void between two adjacent bone ends, providing a cushion between the bone ends to prevent impingement of the bone ends while providing time for tissue to infiltrate into the space occupied by the implant (41). It has a protracted resorption time of preferably at least three months to allow time for the proliferation of laod-bearing host fibrous tissue in place of the resorbed implant material. The implant (41) preferably is porous with a pore size of greater than about 80 microns in order to enhance infiltration of fibrous tissue. The implant (41) has a modulus in the range of 0.8 to 20 MPa which is soft enough to allow it to conform to surface irregularities of the adjacent bone surfaces while being hard enough to maintain a desired separation between those bones (13, 15, 17, 19) while tissue infiltration replaces the resorbable implant material. The implant (41) may be preformed to the desired shape or alternatively may be formable by the surgeon by methods such as carving with a scalpel. A preferred application for the implant is as a trapezium bone (11) replacement.

公开(公告)号：EP0639959A1

公开(公告)日：1995-03-01

申请号：EP93911618.0

申请日：1993-04-07

申请人： REGEN BIOLOGICS, INC.

发明人： LI, Shu-Tung ,  STONE, Kevin, R.

IPC分类号： A61F2 ,  A61L27

CPC分类号： A61L27/24 ,  A61F2/08 ,  A61F2/28 ,  A61F2/30965 ,  A61F2/38 ,  A61F2002/30062 ,  A61F2002/30131 ,  A61F2002/3023 ,  A61F2002/30677 ,  A61F2002/30736 ,  A61F2002/30957 ,  A61F2002/4276 ,  A61F2002/4279 ,  A61F2002/4282 ,  A61F2002/4284 ,  A61F2002/4289 ,  A61F2002/4292 ,  A61F2002/4294 ,  A61F2002/4297 ,  A61F2210/0004 ,  A61F2230/0013 ,  A61F2230/0069 ,  A61F2310/00365 ,  A61L27/20 ,  A61L27/227 ,  A61L27/26 ,  A61L27/46 ,  A61L27/48 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/452 ,  A61L2430/10 ,  A61L2430/38 ,  C08L89/06 ,  C08L5/08 ,  C08L5/04 ,  C08L1/00 ,  C08L5/00

摘要： Disclosed is a prosthetic ligament (10) comprising a plurality of substantially aligned, elongated filaments (12). Each filament (12) is a dry, porous, volume matrix of biocompatible and bioresorbable fibrils, at least some of which are crosslinked. The fibrils are short segments of longer fibers of polymeric connective tissue components, or analogs thereof. Each filament (12) establishes a bioresorbable scaffold adapted for ingrowth of ligament fibroblasts, the scaffold and the ingrown fibroblasts supporting natural ligament tensile forces. Also disclosed are methods of fabricating the prosthetic ligament (10), and methods of regenerating ligamentous tissue in vivo.

公开(公告)号：EP0324852A4

公开(公告)日：1990-04-10

申请号：EP88908459

申请日：1988-07-20

申请人： STONE KEVIN R

发明人： STONE KEVIN R

IPC分类号： A61F2/00 ,  A61F2/02 ,  A61F2/28 ,  A61F2/30 ,  A61F2/38 ,  A61F2/42 ,  A61L27/20 ,  A61L27/22 ,  A61L27/24 ,  A61L27/26 ,  A61L27/46 ,  A61L27/48 ,  A61L27/54 ,  A61L27/58

CPC分类号： A61L27/58 ,  A61F2/28 ,  A61F2/30756 ,  A61F2/3094 ,  A61F2/30965 ,  A61F2/38 ,  A61F2/3872 ,  A61F2002/30062 ,  A61F2002/30131 ,  A61F2002/30205 ,  A61F2002/30677 ,  A61F2002/30736 ,  A61F2002/3082 ,  A61F2002/30879 ,  A61F2002/30904 ,  A61F2002/4276 ,  A61F2002/4279 ,  A61F2002/4282 ,  A61F2002/4284 ,  A61F2002/4289 ,  A61F2002/4292 ,  A61F2002/4294 ,  A61F2002/4297 ,  A61F2210/0004 ,  A61F2230/0013 ,  A61F2230/0067 ,  A61F2310/00365 ,  A61L27/20 ,  A61L27/227 ,  A61L27/24 ,  A61L27/26 ,  A61L27/46 ,  A61L27/48 ,  A61L2430/06 ,  Y10S128/08 ,  C08L5/08 ,  C08L5/00 ,  C08L1/00 ,  C08L89/06

摘要： A prosthetic meniscus is disclosed which can be implanted in a humanoid knee, and which can act as a scaffold for regrowth of native meniscal tissues. The meniscus comprises a three dimensional array of collagen fibers interspersed with glycosaminoglycan molecules. The collagen fibers are present at a concentration of about 65 to 98 percent by dry weight, and the glycosaminoglycan molecules are present at a concentration of about 1 to 25 percent by dry weight. Crosslinks are provided by at least a portion of the glycosaminoglycan molecules, and may consist of at least one of the group comprising chondroitan 4-sulfate, chondroitan 6-sulfate, keritan sulfate, dermatan sulfate, heparin sulfate, and hyaluronic acid.

公开(公告)号：EP2276427B1

公开(公告)日：2018-02-21

申请号：EP09761871.4

申请日：2009-05-18

申请人： Stryker European Holdings I, LLC

发明人： LUSSIEZ, Bruno ,  PRANDI, Bernard

IPC分类号： A61F2/42

CPC分类号： A61F2/4241 ,  A61F2/30767 ,  A61F2/4225 ,  A61F2/4261 ,  A61F2002/30214 ,  A61F2002/30286 ,  A61F2002/3054 ,  A61F2002/30604 ,  A61F2002/30606 ,  A61F2002/30607 ,  A61F2002/30616 ,  A61F2002/30649 ,  A61F2002/3069 ,  A61F2002/30822 ,  A61F2002/30878 ,  A61F2002/30934 ,  A61F2002/4258 ,  A61F2002/4276 ,  A61F2002/4631 ,  A61F2230/0063 ,  A61F2230/0067 ,  A61F2250/0062 ,  A61F2310/00029 ,  A61F2310/00161 ,  A61F2310/00179 ,  A61F2310/00574 ,  A61F2310/0058 ,  A61F2310/00796