公开(公告)号：EP2027163A1

公开(公告)日：2009-02-25

申请号：EP07725927.3

申请日：2007-06-08

申请人： Merck Patent GmbH

发明人： IRGUM, Knut ,  LIME, Fredrik

IPC分类号： C08F2/48 ,  C08F12/36 ,  B01J20/26 ,  C08F212/06 ,  C08F220/02 ,  C08F2/06

CPC分类号： C08F2/48 ,  B01D15/305 ,  B01D15/327 ,  B01D15/361 ,  B01J20/26 ,  B01J20/261 ,  B01J20/265 ,  B01J20/267 ,  B01J20/28004 ,  B01J20/28019 ,  B01J20/285 ,  C08F212/08 ,  C08F212/14 ,  C08F212/36 ,  C08F220/06 ,  C08F220/26 ,  C08F220/30 ,  C08F2220/325 ,  Y10T428/2982

摘要： The invention relates to a polymeric material comprising crosslinked spherical particles that are obtained by photoinitiated precipitation polymerization of crosslinking monomer and optionally a further monomer in the presence of an initiator and a solvent. It also relates to a method for producing the material and a chromatography column containing the material.

公开(公告)号：EP3746203B1

公开(公告)日：2024-08-21

申请号：EP19709103.6

申请日：2019-01-28

IPC分类号： G01N30/34 ,  B01D15/16 ,  B01D15/32 ,  B01D15/42 ,  B01J20/283 ,  B01J20/287 ,  G01N30/72 ,  B01D15/30

CPC分类号： B01D15/166 ,  B01D15/305 ,  B01D15/327 ,  G01N30/34 ,  G01N30/7233 ,  B01D15/325 ,  B01D15/426 ,  B01J20/283 ,  B01J20/287 ,  G01N30/7266

公开(公告)号：EP3141894A4

公开(公告)日：2017-11-15

申请号：EP15789114

申请日：2015-03-19

申请人： SHOWA DENKO KK

发明人： KONDO HIDEYUKI ,  SASUGA JUNJI ,  SHUKUYA TAKAYUKI

IPC分类号： G01N30/72 ,  B01D15/36 ,  B01D15/38 ,  G01N27/62 ,  G01N30/02 ,  G01N30/26 ,  G01N30/56 ,  G01N30/88

CPC分类号： G01N30/52 ,  B01D15/363 ,  B01D15/3847 ,  G01N27/62 ,  G01N30/02 ,  G01N30/26 ,  G01N30/56 ,  G01N30/6052 ,  G01N30/72 ,  G01N30/7233 ,  G01N30/88 ,  G01N30/96 ,  B01D15/305

摘要： A mass spectrometry method by a liquid chromatograph-mass spectrometer that can detect an organic acid with high sensitivity by retaining, separating and eluting the organic acid without adding any nonvolatile substance to a mobile phase and without receiving any restriction of a ratio of a water-soluble organic solvent, and an analytical column are provided. The mass spectrometry method is a mass spectrometry method for an organic acid by a liquid chromatograph-mass spectrometer, wherein a column packed with a hydrophilic polymer having an anion-exchange group is used, and as a mobile phase, a water-soluble organic solvent-water mixed solution is used. The analytical column is a column for liquid chromatography for an organic acid, in which a polyether ether ketone (PEEK) resin housing for liquid chromatography is packed with a hydrophilic polymer having an anion-exchange group.

公开(公告)号：EP3113857A4

公开(公告)日：2017-11-15

申请号：EP15758913

申请日：2015-02-27

申请人： WATERS TECHNOLOGIES CORP

发明人： BROUSMICHE DARRYL W ,  FAIRCHILD JACOB N ,  HILL JASON F ,  ISAAC GIORGIS ,  MORRIS MICHAEL F ,  WYNDHAM KEVIN D

IPC分类号： B01D15/08 ,  B01D15/26 ,  B01J20/32

CPC分类号： B01J20/283 ,  B01D15/26 ,  B01D15/30 ,  B01D15/305 ,  B01D15/322 ,  B01D15/40 ,  B01D53/025 ,  B01J20/22 ,  B01J20/28004 ,  B01J20/28016 ,  B01J20/28042 ,  B01J20/28057 ,  B01J20/28059 ,  B01J20/28061 ,  B01J20/28064 ,  B01J20/28066 ,  B01J20/28069 ,  B01J20/28071 ,  B01J20/28073 ,  B01J20/28076 ,  B01J20/28078 ,  B01J20/28083 ,  B01J20/28085 ,  B01J20/282 ,  B01J20/284 ,  B01J20/285 ,  B01J20/288 ,  B01J20/289 ,  B01J20/3085 ,  B01J20/32 ,  B01J20/3204 ,  B01J20/3206 ,  B01J20/3208 ,  B01J20/3234 ,  B01J20/3246 ,  B01J20/3285 ,  B01J20/3293 ,  B01J2220/54 ,  B01J2220/80 ,  C07F7/1836

摘要： The present invention provides a chromatographic stationary phase material various different types of chromatography. One example chromatographic stationary phase is represented by Formula 1 [X](W)a(Q)b(T)c (Formula 1). X can be a high purity chromatographic core composition. W can be absent and/or can include hydrogen and/or can include hydroxyl on the surface of X. Q can be bound directly to X and can include a first hydrophilic, polar, ionizable, and/or charged functional group that chromatographically interacts with the analyte. T can be bound directly to X and can include a second hydrophilic, polar, ionizable, and/or charged functional group that chromatographically interacts with the analyte. Additionally, Q and T can essentially eliminate chromatographic interaction between the analyte, and X and W, thereby minimizing retention variation over time (drift or change) under chromatographic conditions utilizing low water concentrations.

公开(公告)号：EP3007792A4

公开(公告)日：2017-05-03

申请号：EP14810327

申请日：2014-06-10

申请人： WATERS TECHNOLOGIES CORP

发明人： WYNDHAM KEVIN DANIEL ,  FAIRCHILD JACOB NATHAN ,  IRANETA PAMELA C ,  SHINER STEPHEN JAMES ,  BROUSMICHE DARRYL W ,  WALSH DANIEL P

IPC分类号： B01D15/08 ,  B01J20/283 ,  B01J20/286

CPC分类号： B01D15/08 ,  B01D15/305 ,  B01D15/322 ,  B01D15/40 ,  B01J20/28004 ,  B01J20/28016 ,  B01J20/28057 ,  B01J20/28059 ,  B01J20/28061 ,  B01J20/28069 ,  B01J20/28071 ,  B01J20/28078 ,  B01J20/28083 ,  B01J20/28085 ,  B01J20/283 ,  B01J20/286 ,  B01J20/3234 ,  C07F7/12 ,  C07F7/1804

摘要： The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for its preparation and separations devices containing the chromatographic material; separations devices, chromatographic columns and kits comprising the same; and methods for the preparation thereof. The chromatographic materials of the invention are superficially porous chromatographic particulate materials comprising sized less than 2 microns.

摘要翻译： 本发明提供了新颖的色谱材料，例如，用于色谱分离，处理用于其制备方法和分离含层析材料的装置; 分离设备，色谱柱和试剂盒，其包括相同的; 和其制备方法。 本发明的层析材料是表面上含有尺寸小于2微米的多孔色谱颗粒材料。

公开(公告)号：EP2745904B1

公开(公告)日：2015-12-16

申请号：EP13198653.1

申请日：2013-12-19

申请人： Dionex Corporation

发明人： LIU, Xiaodong ,  CHEN, Jinhua ,  POHL, Christopher A.

IPC分类号： B01D15/38 ,  B01J43/00 ,  B01J20/28 ,  B01J20/32

CPC分类号： B01D15/3847 ,  B01J20/28097 ,  B01J20/288 ,  B01J20/3221 ,  B01J20/3285 ,  B01J20/3295 ,  B01J43/00 ,  B01D15/305 ,  B01D15/362 ,  B01D15/363 ,  B01D15/364

公开(公告)号：EP2121014B1

公开(公告)日：2013-08-21

申请号：EP08713635.4

申请日：2008-01-08

申请人： Bio-Rad Laboratories, Inc.

发明人： GAGNON, Peter S.

IPC分类号： A61K39/395 ,  C07K16/00 ,  C07K1/16

CPC分类号： C07K16/065 ,  B01D15/305 ,  B01D15/327 ,  B01D15/361 ,  B01D15/3804 ,  B01D15/3847 ,  B01J20/048 ,  B01J20/282

公开(公告)号：EP2598872A1

公开(公告)日：2013-06-05

申请号：EP11723399.9

申请日：2011-05-19

申请人： joint analytical systems GmbH

发明人： KITTLAUS, Stefan ,  RADTKE, Joerg

IPC分类号： G01N30/08 ,  G01N30/20 ,  G01N30/40 ,  G01N30/46 ,  G01N1/40

CPC分类号： G01N30/461 ,  G01N1/4044 ,  G01N1/405 ,  G01N30/06 ,  G01N30/08 ,  G01N30/20 ,  G01N30/40 ,  G01N30/46 ,  G01N30/462 ,  G01N2030/085 ,  B01D15/305

摘要： An arrangement (10) for preparing samples and analyzing pesticides in samples contains an HILIC chromatography column (14) with a first pump (12) for a predominantly low-water and/or non-polar solvent; an SPE enrichment arrangement (22); a second chromatography column (28) with a second pump (18) for a predominantly water-rich and/or polar solvent; a detector (32); and a valve arrangement (20, 24) for controlling the stream of sample and matrix, which valve arrangement is designed in such a way that the sample stream, in a first switching state (fig. 1) of the valve arrangement, can be conducted from the HILIC chromatography column (14) to the SPE enrichment arrangement (22) and, in a second switching state (fig. 2), the sample enriched in the SPE enrichment arrangement (22) can be conducted in the opposite direction from the SPE enrichment arrangement (22) through the second chromatography column (28) to the detector (32).

公开(公告)号：EP2561345A2

公开(公告)日：2013-02-27

申请号：EP11766589.3

申请日：2011-04-05

申请人： Purdue Research Foundation

发明人： WIRTH, Mary, Jean ,  RANASINGHE KODITHUWAKKUGE, Sampath ,  YERNENI, Charu ,  BIRDSALL, Robert

IPC分类号： G01N30/60

CPC分类号： B01D15/206 ,  B01D15/168 ,  B01D15/305 ,  B01D15/325 ,  B01J20/283 ,  G01N30/56 ,  G01N2030/562 ,  G01N2030/565 ,  G01N2030/8831

摘要： Improved methods for packing a chromatographic column and columns packed by these methods are provided. The methods include introducing a packing material into a chromatographic column, while simultaneously ultrasonicating and applying pressure to the packing material to form a packed column with radial homogeneity.

公开(公告)号：EP2217356A4

公开(公告)日：2012-02-29

申请号：EP08843483

申请日：2008-11-03

申请人： BIOCIUS LIFE SCIENCES INC

发明人： OZBAL CAN C ,  JONAS MAXINE ,  LAMARR WILLIAM A ,  VERNIKOV EDUARD

IPC分类号： G01N30/72 ,  B01D59/44

CPC分类号： H01J49/0431 ,  B01D15/305 ,  B01D15/34 ,  B01D15/361 ,  G01N1/405 ,  G01N30/02 ,  G01N30/24 ,  G01N30/7266 ,  G01N2030/207 ,  G01N2030/8411 ,  B01D15/36

摘要： One embodiment of the invention provides a sample injection system including a vacuum source, a conduit in communication with the vacuum source, a fluid sensor configured to detect the presence of the fluid in the conduit, a sample loop in communication with the conduit; and a sipper in communication with the sample loop.

摘要翻译： 本发明的一个实施例提供了一种样品注射系统，其包括真空源，与真空源连通的导管，被配置为检测导管中流体的存在的流体传感器，与导管连通的样品回路; 和与样品回路通信的吸嘴。