公开(公告)号：EP2333540A4

公开(公告)日：2015-08-12

申请号：EP09814195

申请日：2009-06-04

申请人： SHISEIDO CO LTD

发明人： KANDA TAKETOSHI ,  IGARASHI YASUO ,  SAKUMA KENICHI ,  TOUJO YOUSUKE

IPC分类号： G01N30/88 ,  B01D15/08 ,  B01D15/30 ,  B01D15/32 ,  B01D15/36 ,  B01J20/281 ,  B01J20/288 ,  B01J20/289 ,  B01J20/32 ,  G01N30/26

CPC分类号： B01D15/305 ,  B01D15/322 ,  B01D15/364 ,  B01J20/261 ,  B01J20/28016 ,  B01J20/28019 ,  B01J20/288 ,  B01J20/289 ,  B01J20/3204 ,  B01J20/3219 ,  B01J20/3259 ,  B01J20/3285 ,  Y10T428/2982

摘要： The object of the present invention is to provide a packing material and a separation method that manifest excellent hydrophilic interactions. The present invention provides a packing material for hydrophilic interaction chromatography consisting of a modified support treated with the surface modifier represented by the following formula (6) or (7). (In this formula, m denotes 2-6 and n denotes 1-4. X 1 , X 2 , and X 3 , independent of each other, denote a methoxy group, ethoxy group, or halogen. Up to two of X 1 , X 2 and X 3 can be any of the following groups: a methyl group, ethyl group, propyl group, isopropyl group, butyl group, or isobutyl group. )

公开(公告)号：EP1841527A2

公开(公告)日：2007-10-10

申请号：EP05854430.5

申请日：2005-12-16

申请人： MALLINCKRODT BAKER, Inc.

发明人： DEORKAR, Nandu ,  BUSS, Robert, C. ,  MLADOSICH, Joseph, M. ,  BOUIS, Paul, A.

IPC分类号： B01J20/22

CPC分类号： B01J41/14 ,  B01D15/327 ,  B01D15/363 ,  B01D15/364 ,  B01J20/261 ,  B01J20/262 ,  B01J20/265 ,  B01J20/28004 ,  B01J20/285 ,  B01J20/288 ,  B01J20/3092 ,  B01J20/321 ,  B01J20/3255 ,  B01J20/3272 ,  B01J20/328 ,  B01J20/3285 ,  B01J2220/52 ,  B01J2220/54 ,  B01J2220/58 ,  C07K1/165

摘要： This invention concerns the preparation and use of novel polymeric chromatographic media and preferably mixed mode polymeric chromatographic media. In accordance with the present invention, polymeric media is prepared using polymeric particles derivatized with polyethyleneimine, and preferably such polyethyleneimine derivatized polymeric particles further functionalized with appropriate reactants. The polymeric chromatographic media is especially useful for bioseparations.

公开(公告)号：EP1825763A1

公开(公告)日：2007-08-29

申请号：EP06003736.3

申请日：2006-02-23

申请人： ITO EN, LTD.

发明人： Takihara, Takanobu c/o ITO EN, LTD. ,  Kubota, Yuji c/o ITO EN, LTD.

IPC分类号： A23L1/015 ,  B01D15/08 ,  B01J47/00 ,  C02F1/42

CPC分类号： B01D15/364 ,  A23L2/02 ,  A23L2/78 ,  A23L5/273 ,  B01D15/361 ,  B01J43/00 ,  C02F1/42

摘要： Disclosed is a method of removing nitric acid from an aqueous liquid containing various components such as vegetable extract, and nitrate ion is removed selectively without spoiling the taste or other components, by subjecting the aqueous liquid to chromatographic treatment with an amphoteric ion exchanger to separate nitrate ion from other components contained in the aqueous liquid. A nitric acid-reduced drink is produced by preparing a raw drink material comprising an extract or juice of plant tissue; removing nitric acid from the raw drink material with use of the method of removing nitric acid from an aqueous liquid as described above; and preparing a drink using the raw drink material after the removing of nitric acid.

摘要翻译： 公开了由硝酸除去硝酸wässrige含有各种成分的液体的方法包括：如植物提取物和硝酸根离子被不损害味道或其它组分选择性地除去，通过使wässrige液体在两性离子交换剂与以色谱处理以分离 离子从包含在液体wässrige其它组分。 甲硝酸还原饮料是通过制备原始饮料材料，其包含以提取或植物组织的产生汁; 从使用从在如上所述wässrige液体除去硝酸的方法的原始饮料原料中除去硝酸; 和准备使用原始饮料原料硝酸的去除后的饮品。

公开(公告)号：EP1137466A1

公开(公告)日：2001-10-04

申请号：EP99958580.5

申请日：1999-11-09

申请人： Irgum, Knut ,  Viklund, Camilla

发明人： Irgum, Knut ,  Viklund, Camilla

IPC分类号： B01D15/08

CPC分类号： B01J39/26 ,  B01D15/364 ,  B01J20/28078 ,  B01J20/286 ,  B01J20/289 ,  B01J20/3092 ,  B01J20/321 ,  B01J20/3217 ,  B01J20/3219 ,  B01J20/3251 ,  B01J20/3255 ,  B01J20/3278 ,  B01J20/3285 ,  B01J20/3293 ,  B01J41/20 ,  B01J43/00 ,  B01J2220/54 ,  B01J2220/58 ,  B01J2220/82 ,  G01N2030/528

摘要： The present invention relates to a novel sorbent suitable for use as a stationary phase in a chromatography column, the core of which consists of an organic polymer of synthetic or natural origin. Further, the carrier according to the invention exhibits a plurality of covalently bonded non-aromatic zwitterionic groups on its surface. Additionally, the invention also relates to a method for purifying a particular biological macromolecule, such as a protein or a nucleic acid, by zwitterionic ion exchange chromatography as well as an ion exchange column suitable for use in zwitterionic ion exchange chromatography.

公开(公告)号：EP3227450A1

公开(公告)日：2017-10-11

申请号：EP15866164.5

申请日：2015-11-23

申请人： Archer Daniels Midland Company

发明人： BINDER, Thomas ,  HILALY, Ahmad K. ,  SUDHARSAN, Naveen S. ,  MANI, Kris N. ,  SCHULTZ, Mitchell Jo

IPC分类号： C12P7/40 ,  C12P1/02 ,  B01D15/36 ,  B01J20/26

CPC分类号： C07C51/377 ,  B01D3/145 ,  B01D15/1821 ,  B01D15/364 ,  B01D61/027 ,  B01D2325/36 ,  B01J43/00 ,  C07C51/412 ,  C07C51/43 ,  C07C51/44 ,  C07C51/47 ,  C12P7/40 ,  C12P7/56 ,  C12Y101/01027 ,  C07C57/04 ,  C07C59/08

摘要： A process is described for making acrylic acid from dextrose, which comprises fermenting dextrose; removing solids from the resulting fermentation broth; removing lactic acid from the clarified broth by extraction into an organic solvent; separating out the lactic acid-loaded organic solvent while recycling at least a portion of the remainder back to the fermentation step; reacting the lactic acid with ammonia to provide a dehydration feed comprising ammonium lactate while preferably recycling the organic solvent; carrying out a vapor phase dehydration of the ammonium lactate to produce a crude acrylic acid product; and purifying the crude acrylic acid by distillation followed by melt crystallization, chromatography or both melt crystallization and chromatography.

摘要翻译： 描述了由葡萄糖制备丙烯酸的方法，其包括发酵葡萄糖; 从所得发酵液中除去固体; 通过萃取到有机溶剂中从澄清的发酵液中除去乳酸; 分离出负载乳酸的有机溶剂，同时将至少一部分剩余物循环回发酵步骤; 使乳酸与氨反应以提供包含乳酸铵的脱水进料，同时优选再循环有机溶剂; 进行乳酸铵的气相脱水以产生粗丙烯酸产物; 并通过蒸馏纯化粗丙烯酸，然后熔融结晶，层析或熔融结晶和色谱二者。

公开(公告)号：EP2464374B1

公开(公告)日：2016-05-04

申请号：EP10747327.4

申请日：2010-08-11

申请人： Xellia Pharmaceuticals ApS

发明人： BRUNSVIK, Anders

IPC分类号： C07K7/56

CPC分类号： C07K1/20 ,  A61K38/00 ,  B01D15/305 ,  B01D15/322 ,  B01D15/364 ,  B01D15/426 ,  C07K7/56 ,  C07K7/64

公开(公告)号：EP1674570B1

公开(公告)日：2010-12-01

申请号：EP05027215.2

申请日：2005-12-13

申请人： Samsung Electronics Co., Ltd.

发明人： Hwang, Kyu-youn ,  Kim, Joon-ho ,  Yoo, Chang-eun ,  Lee, Hun-joo ,  Lim, Hee-kyun ,  Jeong, Sung-young c/o Samsung Advanced Institute of Technology, ,  Shim, Jeo-young

IPC分类号： C12N15/10 ,  C12Q1/68 ,  C07H1/08 ,  C07H21/04

CPC分类号： C12N15/1006 ,  B01D15/361 ,  B01D15/364 ,  B01J20/3285 ,  B01J43/00 ,  C12Q1/6806 ,  C12Q2527/119 ,  C12Q2523/308

公开(公告)号：EP1674570A3

公开(公告)日：2008-08-13

申请号：EP05027215.2

申请日：2005-12-13

申请人： Samsung Electronics Co., Ltd.

发明人： Hwang, Kyu-youn ,  Kim, Joon-ho ,  Yoo, Chang-eun ,  Lee, Hun-joo ,  Lim, Hee-kyun, 147-602 Hwanggol Maeul ,  Jeong, Sung-young, c/o Samsung Adv.Inst. of Techn ,  Shim, Jeo-young

IPC分类号： C12N15/10 ,  C12Q1/68 ,  C07H1/08 ,  C07H21/04

CPC分类号： C12N15/1006 ,  B01D15/361 ,  B01D15/364 ,  B01J20/3285 ,  B01J43/00 ,  C12Q1/6806 ,  C12Q2527/119 ,  C12Q2523/308

摘要： A method of isolating nucleic acid from a sample containing nucleic acid is provided. The method includes contacting the sample with a bifunctional material that contains an amino group and a carboxyl group and is positively charged at a first pH to allow binding of the nucleic acid to the bifunctional material; and extracting the nucleic acid at a second pH higher than the first pH from the complex.

公开(公告)号：EP3060911A1

公开(公告)日：2016-08-31

申请号：EP14855837.2

申请日：2014-10-15

申请人： Agency for Science, Technology and Research

发明人： GAGNON, Peter Stanley

IPC分类号： G01N33/48 ,  A61K35/16 ,  A61K35/22

CPC分类号： G01N33/5076 ,  A61K35/12 ,  B01D15/364 ,  G01N33/5005

摘要： A method of isolating exosomes includes conducting at least one purification step in the presence of an organic zwitterion having a molecular weight of less than about 350 Daltons, a buffering pK of a negatively charged portion of the organic zwitterion is at least one full pH unit below an operating pH at which the at least one purification step is conducted, and a buffering pK of the positively charged portion of the organic zwitterion is at least one full pH unit above the operating pH.

摘要翻译： 分离外来体的方法包括在分子量小于约350道尔顿的有机两性离子存在下进行至少一个纯化步骤，有机两性离子的带负电荷的部分的缓冲pK为至少一个完整的pH单位， 进行至少一个纯化步骤的操作pH，并且有机两性离子的带正电部分的缓冲pK是高于操作pH的至少一个完整的pH单位。

公开(公告)号：EP2745904B1

公开(公告)日：2015-12-16

申请号：EP13198653.1

申请日：2013-12-19

申请人： Dionex Corporation

发明人： LIU, Xiaodong ,  CHEN, Jinhua ,  POHL, Christopher A.

IPC分类号： B01D15/38 ,  B01J43/00 ,  B01J20/28 ,  B01J20/32

CPC分类号： B01D15/3847 ,  B01J20/28097 ,  B01J20/288 ,  B01J20/3221 ,  B01J20/3285 ,  B01J20/3295 ,  B01J43/00 ,  B01D15/305 ,  B01D15/362 ,  B01D15/363 ,  B01D15/364