公开(公告)号：EP2467466A4

公开(公告)日：2014-06-25

申请号：EP11778349

申请日：2011-05-05

申请人： ALLTECH ASSOCIATES INC

发明人： SAARI-NORDHAUS RAAIDAH ,  GAITA ROMULUS ,  MENDOZA WASHINGTON ,  ANDERSON JAMES ,  ANDERSON SCOTT

IPC分类号： G01N30/82 ,  C12M1/36 ,  G01N21/84 ,  G01N30/74 ,  G01N30/84 ,  G01N35/10

CPC分类号： G01N30/82 ,  G01N30/74 ,  G01N30/78 ,  G01N30/84 ,  G01N35/1097 ,  G01N2030/8447

公开(公告)号：EP2376209A1

公开(公告)日：2011-10-19

申请号：EP09832242.3

申请日：2009-12-10

申请人： Alltech Associates Inc.

发明人： ANDERSON, James, M. ,  PRESANA, Titus ,  SETHUPACKIAM, Sethulingam ,  CHODAVARAPU, Surya, Kiran, L. ,  GOLDSMMITH, Louie

IPC分类号： B01D15/10

CPC分类号： B01D15/22 ,  G01N30/6017 ,  G01N30/6026 ,  G01N30/606 ,  G01N30/6091

摘要： Chromatography columns are disclosed. Methods of making chromatography columns and methods of using chromatography columns are also disclosed.

公开(公告)号：EP2374008A1

公开(公告)日：2011-10-12

申请号：EP09832239.9

申请日：2009-12-10

申请人： Alltech Associates Inc.

发明人： ANDERSON, James, M., Jr. ,  BYSTRON, Josef, P. ,  MENDOZA, Washington, J. ,  SAARI-NORDHAUS, Raaidah ,  PICHA, Neil ,  BLACK, Bruce

IPC分类号： G01N35/10

CPC分类号： G01N30/24 ,  G01N30/20 ,  G01N35/00732 ,  G01N2030/201 ,  G01N2035/0493 ,  Y10T29/49826 ,  Y10T137/86493

摘要： Automated sample injection apparatus, multiport valves, and chromatography systems containing an automated sample injection apparatus and/or a multiport valve are disclosed. Methods of making and using automated sample injection apparatus and multiport valves within chromatography systems are also disclosed.

公开(公告)号：EP1640714A2

公开(公告)日：2006-03-29

申请号：EP05028383.7

申请日：2000-10-13

申请人： Alltech Associates, Inc.

发明人： Anderson, James M. Jr. ,  Saari-Nordhaus, Raaidah ,  Benedict, Bart C. ,  Sims, Carl W. ,  Gurner, Yuri ,  Pham, Hung Anthony

IPC分类号： G01N30/96

CPC分类号： G01N30/96 ,  B01D15/367 ,  G01N30/34 ,  G01N2001/4016 ,  G01N2030/965

摘要： A method of detecting analyte ions by continuous electrochemically suppressed ion chromatography comprising: (a) flowing analyte ions in an aqueous mobile phase comprising electrolyte through an analytical column separating means to form an aqueous chromatography effluent comprising separated analyte ions and electrolyte; (b) flowing the aqueous chromatography effluent through a suppressor means for splitting the chromatography effluent into a first chromatography effluent flow stream and a second chromatography effluent flow stream; (c) applying an electrical potential in the suppressor means such that electrolyte is electrochemically driven into the first chromatography effluent stream and away from the second chromatography effluent flow stream; (d) flowing the second chromatography effluent flow stream out of the suppressor means; (e) detecting the analyte ions in the second chromatography effluent flow stream.

摘要翻译： 通过连续电化学抑制的离子色谱检测分析物离子的方法，其包括：（a）通过分析柱分离装置将包含电解质的水性流动相中的分析物离子流动，以形成包含分离的分析物离子和电解质的含水层析流出物; （b）使含水层析流出物流过抑制剂装置，用于将色谱流出物分离成第一色谱流出物流和第二色谱流出物流; （c）在抑制器装置中施加电势使得电解质被电化学驱动进入第一色谱流出物流并且远离第二层析流出物流; （d）使第二层析流出物流流出抑制装置; （e）检测第二层析流出物流中的分析物离子。

公开(公告)号：EP1366817A3

公开(公告)日：2004-03-10

申请号：EP03020294.9

申请日：1996-03-01

申请人： Alltech Associates, Inc.

发明人： Anderson, James M., Jr. ,  Saari-Nordhaus, Raaidah ,  Sims, Carl W. ,  Gerner, Yuri E.

IPC分类号： B01J39/06 ,  B01D15/08 ,  G01N30/52 ,  G01N30/96

CPC分类号： G01N27/453 ,  B01D15/361 ,  B01D15/3885 ,  B01J39/26 ,  G01N30/02 ,  G01N30/34 ,  G01N30/468 ,  G01N30/52 ,  G01N30/96 ,  G01N2030/285 ,  G01N2030/965 ,  G01N2030/0035 ,  B01D15/362

摘要： A system for generating a high purity eluant that can be used in detecting sample ions comprises: a water source, an eluant generating source, and a fluid flow path that is in fluid communication with the water source, wherein the fluid flow path is the only path for liquid flow through the eluant generating source. By electrolysis of water and combining electrolysis ions with counter ions of a sample a high-purity eluant is formed.

公开(公告)号：EP1048351B1

公开(公告)日：2003-09-10

申请号：EP00115245.3

申请日：1996-03-01

申请人： Alltech Associates, Inc.

发明人： Anderson, James M, Jr. ,  Saari-Nordhaus, Raaidah ,  Sims, Carl W. ,  Gerner, Yuri E.

IPC分类号： B01J39/06 ,  B01D15/08 ,  G01N30/52 ,  G01N30/96

CPC分类号： G01N27/453 ,  B01D15/361 ,  B01D15/3885 ,  B01J39/26 ,  G01N30/02 ,  G01N30/34 ,  G01N30/468 ,  G01N30/52 ,  G01N30/96 ,  G01N2030/285 ,  G01N2030/965 ,  G01N2030/0035 ,  B01D15/362

公开(公告)号：EP1107817A4

公开(公告)日：2002-02-13

申请号：EP99920352

申请日：1999-05-04

申请人： ALLTECH ASSOCIATES INC

发明人： ANDERSON JAMES M JR ,  SAARI-NORDHAUS RAAIDAH

IPC分类号： G01N27/06 ,  B01D15/04 ,  B01D15/08 ,  G01N30/60 ,  G01N30/64 ,  G01N30/96

CPC分类号： G01N30/96 ,  G01N2030/965

摘要： An integrated suppressor and detector (16) for suppressed ion chromatography includes a stationary phase (39), a fluid flow path, at least first and second regeneration electrodes (37, 38), and at least first and second sensor electrodes (30, 32). Methods of suppressed ion chromatography using the integrated suppressor and detector (16) are also described.

公开(公告)号：EP1092977A1

公开(公告)日：2001-04-18

申请号：EP00122480.7

申请日：2000-10-13

申请人： Alltech Associates, Inc.

发明人： Anderson, James M. Jr. ,  Saari-Nordhaus, Raaidah ,  Benedict, Bart C. ,  Sims, Carl W. ,  Gurner, Yuri ,  Pham, Hung Anthony

IPC分类号： G01N30/96

CPC分类号： G01N30/96 ,  B01D15/367 ,  G01N30/34 ,  G01N2001/4016 ,  G01N2030/965

摘要： Methods and devices for removing gas prior to detecting analyte ions are disclosed. In one aspect of the invention, gas by-products from the suppression of the mobile phase are removed prior to detecting analyte ions at a detector. In another aspect, the amount of dissolved carbonic acid is reduced in a suppressed carbonate/bicarbonate mobile phase by removing carbon dioxide gas.

摘要翻译： 公开了在检测分析物离子之前去除气体的方法和装置。 在本发明的一个方面，在检测器处检测分析物离子之前，除去来自抑制流动相的气体副产物。 另一方面，通过除去二氧化碳气体，在抑制的碳酸盐/碳酸氢盐流动相中溶解的碳酸的量被降低。

公开(公告)号：EP1048351A3

公开(公告)日：2001-01-24

申请号：EP00115245.3

申请日：1996-03-01

申请人： Alltech Associates, Inc.

发明人： Anderson, James M, Jr. ,  Saari-Nordhaus, Raaidah ,  Sims, Carl W. ,  Gerner, Yuri E.

IPC分类号： B01J39/06 ,  B01D15/08 ,  G01N30/52 ,  G01N30/96

CPC分类号： G01N27/453 ,  B01D15/361 ,  B01D15/3885 ,  B01J39/26 ,  G01N30/02 ,  G01N30/34 ,  G01N30/468 ,  G01N30/52 ,  G01N30/96 ,  G01N2030/285 ,  G01N2030/965 ,  G01N2030/0035 ,  B01D15/362

摘要： A system for generating a high purity eluant that can be used in detecting sample ions comprising: a path of fluid flow; a water source (100); an eluant generating source comprising a stationary phase (112) in fluid communication with the path of fluid flow wherein at least a portion of the stationary phase is positioned between a first electrode and a second electrode; a power source (116) in electrical communication with the first and second electrodes; an analytical column (120) comprising ion exchange resin, the analytical column located downstream in the path of fluid flow from the eluant generating source; a suppressor comprising a suppressor stationary phase (122) having exchangeable ions selected from the group consisting of hydronium ions and hydroxide ions, the suppressor being positioned downstream in the path of fluid flow from the analytical column, wherein at least portion of the suppressor stationary phase is positioned between a first suppressor electrode and a second suppressor electrode, the suppressor electrodes being in electrical communication with a power source (123); and a detector (118) positioned downstream in the path of fluid flow from the suppressor.

公开(公告)号：EP0977620A1

公开(公告)日：2000-02-09

申请号：EP98911665.2

申请日：1998-03-13

申请人： Alltech Associates, Inc.

发明人： ANDERSON, James, M., Jr. ,  SAARI-NORDHAUS, Raaidah ,  SIMS, Carl, W. ,  GERNER, Yuri, E.

IPC分类号： B01D15/08

CPC分类号： G01N30/52 ,  B01D15/203 ,  B01D15/361 ,  B01J39/26 ,  G01N30/02 ,  G01N30/34 ,  G01N30/468 ,  G01N30/96 ,  G01N2030/285 ,  G01N2030/965 ,  B01D15/362 ,  G01N2030/0035

摘要： A system and method for electrochemically regenerated ion neutralization and concentration is disclosed. In one aspect of the invention, a system is provided including an HPLC column pump (1), a concentrator column (2), an analytical column (3), a suppressor (4), a detector (5), a mixed bed deionizing resin (6), a sample injector (7), and a neutralization cartridge (9).

摘要翻译： 公开了用于电化学再生离子中和和浓缩的系统和方法。 在本发明的一个方面，提供了一种系统，其包括HPLC柱泵（1），浓缩柱（2），分析柱（3），抑制器（4），检测器（5），混合床去离子 树脂（6），样品注入器（7）和中和盒（9）。