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公开(公告)号：EP0682527B1
公开(公告)日：2002-04-03
申请号：EP94907915.6
申请日：1994-01-27
IPC分类号： A61K39/002 , A61K31/70 , A61K31/715 , A61K33/14 , G01N33/569
CPC分类号： G01N33/569 , A61K39/0003 , G01N33/5308
摘要： The present invention relates to Trichinella vaccines that include at least one tyvelose-containing oligosaccharide or functional equivalent thereof, to Trichinella vaccines that include at least one fucose-containing oligosaccharide or functional equivalent thereof, and to the use of such vaccines to protect animals from Trichinella infections, and particularly from trichinosis caused by Trichinella spiralis infection. Such vaccines can also be used to produce antibodies that are capable of protecting an animal from Trichinella infections and of diagnosing such infections. The present invention also relates to Trichinella diagnostic reagents that include at least one tyvelose-containing oligosaccharide, or functional equivalent thereof, and use of such reagents to detect Trichinella, and particularly Trichinella spiralis infections. The present invention also includes diagnostic kits based on such reagents and anti-Trichinella-spiralis drugs based on the knowledge that tyvelose is produced by Trichinella spiralis parasites.
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32.发明公开METHODS FOR PRODUCING $g(a)-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES 审中-公开用于生产ALPHA酰氧基 - 羰基FROM烯醇式环氧化物
公开(公告)号：EP1169291A1
公开(公告)日：2002-01-09
申请号：EP00918297.3
申请日：2000-03-23
发明人： SHI, Yian
CPC分类号： C07C67/293 , C07B2200/07 , C07C69/76
摘要： The present invention provides a method for producing an α-acyloxy carbonyl compound from an enol ester epoxide stereoselectively using an acid catalyst which is capable of affecting rearrangement of the enol ester epoxide with inversion of stereochemistry. The present invention also provides a method for kinetic resolution of a stereoisomeric mixture of enol ester epoxides using a chiral catalyst. The kinetic resolution generally involves stereoselectively producing one particular enantiomer of α-acyloxy carbonyl compounds from the stereoisomeric mixture of enol ester epoxides.
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公开(公告)号：EP1100534A1
公开(公告)日：2001-05-23
申请号：EP99937611.4
申请日：1999-07-29
IPC分类号： A61K39/00 , A61K39/395
CPC分类号： A61K35/52 , G01N2015/149
摘要： Non-surgical artificial insemination is achieved for sexed and unsexed equines in a commercially practical manner and with dosages of insemination sperm which were not previously thought to be practical for commercial implementation. Practical and field usable techniques for insemination are presented as well as techniques which offer success ratios at level comparable to the existing routine, high dosage unsexed artificial techniques in equines. Improved insemination and sorting systems particularly adapted to use for sex-selected sperm are disclosed.
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公开(公告)号：EP0992095A1
公开(公告)日：2000-04-12
申请号：EP97928907.1
申请日：1997-06-06
IPC分类号： H01S3/30
CPC分类号： H01S4/00
摘要： An extremely compact soft x-ray and/or extreme ultraviolet laser is disclosed that can be repetitively fired within short time intervals. The laser generates a plasma within a capillary (3) by flowing through the capillary (3) a fast high current pulse generated by a very compact liquid dielectric (1) transmission line (9) geometry.
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公开(公告)号：EP0574527B1
公开(公告)日：1998-09-23
申请号：EP92908603.1
申请日：1992-03-05
IPC分类号： A61F2/02
CPC分类号： A61L27/227 , A61F2/0077 , A61F2/062 , A61F2/10 , A61F2/24 , A61F2/2415 , A61L27/3625 , A61L27/3695 , A61L27/38 , A61L27/3804 , A61L27/54 , A61L2300/414 , A61L2300/64 , Y10S623/918 , Y10S623/921
摘要： Tissue which is suitable for transplant is treated with a growth factor and cells which populate the tissue and native cells must be removed, they cannot be "masked" reduce immunogenicity; this increases the longevity of the tissue upon transplant. The preferred growth factor is basic fibroblast growth factor, and the preferred cells are fibroblasts. The tissue can be an allograft or xenograft taken from a cow, pig or other mammal.
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36.发明公开Prototype felv isolates for use in disease models and vaccines 失效Prototypische FeLV-Isolatefürdie Verwendung als Krankheitsmuster oder Impfstoff
公开(公告)号：EP0699758A1
公开(公告)日：1996-03-06
申请号：EP95100871.3
申请日：1989-12-12
CPC分类号： C07K14/005 , A61K39/00 , A61K2039/525 , C12N7/00 , C12N2740/13021 , C12N2740/13022 , C12N2740/13061 , Y10S424/819
摘要： Molecular clones of feline leukemia virus isolates that encode (a) a prototype highly infectious, minimally pathogenic virus, (b) a variant genome that is replication-defective and associated with a fatal immunodeficiency in cats similar to AIDS (FAIDS) or (c) a chimeric genome that is replication-competent and induces FAIDS. These molecular clones may be used to generate cell lines producing infectious virus which is useful in the preparation of vaccines or in the generation of viremia or disease challenge systems.
摘要翻译： 猫科白血病病毒分离株的分子克隆编码（a）原型感染性极低的致病病毒，（b）与艾滋病相似的猫（FAIDS）中复制缺陷并与致命免疫缺陷相关的变异基因组，或（c） 具有复制能力并诱导FAIDS的嵌合基因组。 这些分子克隆可用于产生产生感染性病毒的细胞系，其可用于制备疫苗或产生病毒血症或疾病挑战系统。
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公开(公告)号：EP0630258A1
公开(公告)日：1994-12-28
申请号：EP93913889.0
申请日：1993-05-14
发明人： GRIEVE, Robert, B. , FRANK, Glenn
CPC分类号： A61K39/0003 , A61K39/00 , C07K14/4354
摘要： On a constaté qu'il est possible de protéger aisément des hôtes sensibles aux parasitoses par les nématodes, contre ces infections, lorsque les parasites ne sont pas adaptés à une relation parasite/hôte avec cet hôte. En particulier, des hôtes félins ont été immunisés contre la filaire à l'aide d'une grande variété d'antigènes dérivés du Dirofilaria immitis et de nématodes apparentés. Etant donné que les chats sont des hôtes sensibles à ce parasite non adapté, ces antigènes assurent une protection efficace.
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公开(公告)号：EP0444142A1
公开(公告)日：1991-09-04
申请号：EP90900531.0
申请日：1989-11-06
CPC分类号： C08G73/0688
摘要： L'invention concerne des copolymères de polyquinoline ainsi que des mélanges d'homopolymères et de copolymères de polyquinoline présentant des propriétés uniques. Lesdits copolymères peuvent comprendre des copolymères aléatoires, des copolymères bloc, ainsi que des copolymères tri-bloc.
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39.发明公开ASYMMETRIC HYDROFORMYLATIONS OF PROCHIRAL OLEFINS TO CHIRAL ALDEHYDES IN HIGH ENANTIOMERIC EXCESS 失效前手性烯烃手性醛与大映异构体过量不对称醛化。
公开(公告)号：EP0314759A1
公开(公告)日：1989-05-10
申请号：EP88904854.0
申请日：1988-05-05
CPC分类号： C07D209/48 , B01J31/1658 , B01J31/2414 , B01J2531/0219 , B01J2531/42 , B01J2531/828 , C07B2200/07 , C07C41/50 , C07C45/50 , C07C45/505 , C07C51/14 , C07C2602/42 , C07D333/22 , C07C47/228 , C07C47/23 , C07C47/347 , C07C59/64 , C07C43/303 , C07C43/305
摘要： Des hydroformylations asymétriques d'oléfines chirales peuvent être obtenues en mettant en contact, dans des conditions d'hydroformylation, une oléfine contenant un centre prochiral avec de l'hydrogène et de l'oxyde de carbone en présence d'un catalyseur comprenant un complexe de platine II et de N-(t-butoxycarbonyl)-2S,4S)-4-(diphénylphosphino)-2-[(diphénylphosphino)méthyl] pyrrolidine et du chlorure stanneux, et en extrayant l'aldéhyde chiral résultant à mesure qu'il se forme. Un procédé préféré d'extraction de l'aldéhyde chiral résultant consiste à utiliser un agent d'emprisonnement tel qu'un orthoformate de triéthyle, un orthoformate de triméthyle, un orthoacétate de triéthyle, un orthoacétate de triméthyle, un diéthyl-cétal d'acétone et un diméthyl-acétal d'acétone utilisé en présence d'un support catalyseur à l'état solide tel qu'un polystyrène réticulé.
摘要翻译： 手性烯烃的醛化不对称可通过接触加氢甲酰化条件下，对含有烯烃与氢气和一氧化碳的前手性中心在一种催化剂，包含铂II和N-（叔丁氧羰基）的配合物的存在下可以获得 - （2S， 4S）-4-（二苯基膦基）-2 - [（二苯基膦基）甲基]吡咯烷和氯化亚锡，并且在其形成时除去所得的手性醛。 除去所得的手性醛的优选方法是通过使用捕集剂：如原甲酸三乙酯，原甲酸三甲酯，原乙酸三乙酯，原乙酸三甲酯，丙酮二乙基缩酮，并在固体催化剂载体的存在下使用丙酮二甲基缩醛：例如交 - 连接的聚苯乙烯。
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40.发明公开
公开(公告)号：EP0180305A2
公开(公告)日：1986-05-07
申请号：EP85306143.0
申请日：1985-08-30
IPC分类号： C07D251/50 , A01N43/70 , G01N33/53 , A61K39/385 , A61K39/395 , C07K1/00 , C07K7/00
CPC分类号： G01N33/531 , Y10S435/961 , Y10S436/819 , Y10S530/806 , Y10S530/807
摘要： A compound of the general formula:
in which n is an integer from 3 to 13 and R ist hydrogen or methyl.摘要翻译： 通式的化合物：...
...，其中n是从3至13的整数，R是氢或甲基。
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