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公开(公告)号：EP3102674A2
公开(公告)日：2016-12-14
申请号：EP15738594.9
申请日：2015-02-06
申请人： BASF SE
发明人： KRAWCZYK, Joanna Martyna , HAEFNER, Stefan , SCHRÖDER, Hartwig , DANTAS COSTA, Esther , ZELDER, Oskar , VON ABENDROTH, Gregory , WITTMANN, Christoph , STELLMACHER, René , BECKER, Judith
CPC分类号： C12N15/52 , C12N1/02 , C12N9/0006 , C12N9/1029 , C12N9/1288 , C12N15/74 , C12P7/46 , C12Y101/01 , C12Y203/01054 , C12Y207/08031
摘要： The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the wcaJ-gene. The present invention also relates to a method for producing an organic compound and to the use of a modified microorganism.
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32.发明公开MODIFIED MICROORGANISM FOR IMPROVED PRODUCTION OF FINE CHEMICALS ON SUCROSE 审中-公开变形金刚石变形金刚石VERBESSERTEN HERSTELLUNG VON FEINCHEMIKALIEN AUF SUCROSE
公开(公告)号：EP3102672A1
公开(公告)日：2016-12-14
申请号：EP15719410.1
申请日：2015-02-05
申请人： BASF SE
发明人： KRAWCZYK, Joanna Martyna , HAEFNER, Stefan , SCHRÖDER, Hartwig , DANTAS COSTA, Esther , ZELDER, Oskar , VON ABENDROTH, Gregory
CPC分类号： C12P7/46 , C07K14/285 , C12N1/20 , C12N15/52
摘要： The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the fruA-gene. The present invention also relates to a method for producing an organic compound and to the use of modified microorganisms.
摘要翻译： 本发明涉及与其野生型相比具有由fruA基因编码的酶的活性降低的修饰微生物。 本发明还涉及有机化合物的制造方法和改性微生物的使用。
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33.发明公开MODIFIED MICROORGANISM FOR IMPROVED PRODUCTION OF ALANINE 审中-公开维多利亚州密克罗尼西亚州VERBESSERTEN HERSTELLUNG VON ALANIN
公开(公告)号：EP3039121A1
公开(公告)日：2016-07-06
申请号：EP14839975.1
申请日：2014-08-18
申请人： BASF SE
发明人： KRAWCZYK, Joanna, Martyna , HAEFNER, Stefan , SCHRÖDER, Hartwig , ZELDER, Oskar , FABARIUS, Jonathan, Thomas
CPC分类号： C12P13/06 , C12N9/0016 , C12R1/01 , C12Y104/01001
摘要： A modified microorganism having, compared to its wildtype, an increased activity of the enzyme that is encoded by the alaD-gene is provided. A method for producing an alanine and the use of modified microorganisms are also provided.
摘要翻译： 本发明涉及与其野生型相比具有由alaD基因编码的酶的活性增加的修饰微生物。 本发明还涉及丙氨酸的制备方法和改性微生物的使用。
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公开(公告)号：EP2247724A1
公开(公告)日：2010-11-10
申请号：EP09713039.7
申请日：2009-02-20
申请人： BASF SE
CPC分类号： C12P13/005 , C12N9/88 , C12P13/02
摘要： The present invention relates to a novel method for the fermentative production of gamma-aminobutyric acid (GABA) by cultivating a recombinant micro-organism expressing an enzyme having a glutamate decarboxylase activity. The present invention also relates to corresponding recombinant hosts, recombinant vectors, expression cassettes and nucleic acids suitable for preparing such hosts as well as to a method for preparing polyamides making use of GABA as obtained fermentative production.
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公开(公告)号：EP2185682A1
公开(公告)日：2010-05-19
申请号：EP08785561.5
申请日：2008-08-14
申请人： BASF SE
摘要： The present invention relates to a novel bacterial strain designated DD1, which has the ability to produce organic acids, in particular succinic acid (SA), which was originally isolated from bovine rumen, and is capable of utilizing glycerol as a carbon source; and variant strains derived there from retaining said capability; as well as to methods of producing organic acids, in particular succinic acid by making use of said microorganism.
摘要翻译： 本发明涉及一种称为DD1的新型细菌菌株，其具有生产有机酸特别是琥珀酸（SA）的能力，其最初是从牛瘤胃中分离出来的，并能够利用甘油作为碳源; 和来自保留所述能力的变体菌株; 以及通过利用所述微生物生产有机酸，特别是琥珀酸的方法。
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37.发明公开VERFAHREN ZUR HERSTELLUNG VON GLUCOSE DURCH ENZYMATISCHE HYDROLYSE VON CELLULOSE, DIE UNTER VERWENDUNG EINER IONISCHEN FLÜSSIGKEIT, WELCHE EIN POLYATOMIGES ANION BESITZT, AUS LIGNOCELLULOSEHALTIGEM MATERIAL GEWONNEN WURDE 审中-公开PROCESS葡萄糖制备BY纤维素的酶水解，使用一个离子液体之一具有POLYATOMIGES阴离子FROM含木素纤维素材料WON WAS
公开(公告)号：EP2126104A1
公开(公告)日：2009-12-02
申请号：EP08708075.0
申请日：2008-01-22
申请人： BASF SE
发明人： BALENSIEFER, Tim , FREYER, Stephan , SCHRÖDER, Hartwig , D'ANDOLA, Giovanni , MASSONNE, Klemens
IPC分类号： C12P19/02
摘要： The invention relates to a method for producing glucose from a starting material containing ligno-cellulose. According to said method, said material is initially treated with an ionic liquid and subsequently undergoes enzymatic hydrolysis. The invention also relates to a method for producing microbial metabolic products, especially ethanol, wherein the obtained glucose also undergoes fermentation.
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公开(公告)号：EP2082045A1
公开(公告)日：2009-07-29
申请号：EP07821516.7
申请日：2007-10-18
申请人： BASF SE
IPC分类号： C12N15/77
CPC分类号： C12N15/77
摘要： The present invention is directed to a method of reducing the amount of at least one polypeptide in a host cell by expressing a nucleotide sequence encoding for the polypeptide in the host cell wherein the nucleotide sequence uses codons that are rarely used according to the codon usage of the host organism. Furthermore, the present invention relates to nucleotide sequences encoding for a polypeptide with a codon usage that has been adjusted to use codons that are only rarely used according to the codon usage of the host organism. The present invention further relates to the use of such sequences and methods for producing fine chemicals such as amino acids, sugars, lipids, oils, carbohydrates, vitamins, cofactors etc.
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