BEGEHBARE KÜHLANLAGE, INSBESONDERE ZUR KRYOKONSERVIERUNG BIOLOGISCHER PROBEN, UND VERFAHREN ZU DEREN BETRIEB
    32.
    发明公开
    BEGEHBARE KÜHLANLAGE, INSBESONDERE ZUR KRYOKONSERVIERUNG BIOLOGISCHER PROBEN, UND VERFAHREN ZU DEREN BETRIEB 审中-公开
    步入式冷却系统,特别适用于冷冻保存生物样品和施工方法

    公开(公告)号:EP2671034A2

    公开(公告)日:2013-12-11

    申请号:EP12702189.7

    申请日:2012-02-01

    IPC分类号: F25D3/10

    摘要: A cooling system (1), especially for cryopreserving biological samples (2), comprises a cooling chamber (100) delimited by a bottom area (110), side walls (120), and a top area (130), and a cooling device (200) for cooling the cooling chamber (100) using liquid nitrogen (220). The bottom area (110) is designed for direct cooling using the liquid nitrogen, and the cooling chamber (100) is dimensioned such that an operator (3) can access and move around in the cooling chamber (100). The bottom area (110) has a platform (111) which is permeable to vapor of the liquid nitrogen (220) and forms a support zone for the operator (3). Methods for operating the cooling system are also described.

    摘要翻译: 的冷却系统(1),尤其是冷冻保存生物样品(2),包括由底部区域(110)定界的冷却室(100),侧壁(120),以及一个顶部区域(130),和一个冷却装置 (200)用于冷却用液氮(220)冷却室(100)。 的底部区域(110)是使用液氮设计用于直接冷却,所述冷却室(100)的尺寸的搜索没有到操作者(3)可以访问和在所述冷却室(100)移动。 的底部区域(110)具有一个平台(111),所有这些是可渗透的液氮(220)的蒸气和形成支撑区供操作(3)。 因此用于操作冷却系统的方法被描述。

    VERFAHREN UND VORRICHTUNG ZUR ÜBERWACHUNG EINER KRYOKONSERVIERTEN BIOLOGISCHEN PROBE
    33.
    发明公开
    VERFAHREN UND VORRICHTUNG ZUR ÜBERWACHUNG EINER KRYOKONSERVIERTEN BIOLOGISCHEN PROBE 有权
    VERFAHREN UND VORRICHTUNG ZURÜBERWACHUNGEINER KRYOKONSERVIERTEN BIOLOGISCHEN PROBE

    公开(公告)号:EP2643682A1

    公开(公告)日:2013-10-02

    申请号:EP11779099.8

    申请日:2011-10-26

    IPC分类号: G01N21/65

    CPC分类号: G01N21/65 G01N21/658

    摘要: The invention relates to a method for monitoring a cryopreserved biological sample (1), comprising the steps of providing the biological sample (1) in a cryopreserved state, measuring at least one Raman spectroscopic sample characteristic by means of a Raman spectroscopic measuring apparatus (10, 20), comparing the at least one sample characteristic with a reference characteristic by means of an evaluating apparatus (30), and providing a state characteristic that depends on the result of the comparison and that is characteristic of a storage state of the biological sample (1). The invention further relates to a monitoring device for cryopreserved samples, in particular for performing said method.

    摘要翻译: 本发明涉及一种用于监测冷冻保存的生物样品(1)的方法,包括以下步骤:提供生物样品(1)处于冷冻保存状态,通过拉曼光谱测量装置(10)测量至少一个拉曼光谱样品特征 ,20),通过评估装置(30)将所述至少一个样本特征与参考特征进行比较,并提供取决于比较结果的状态特征,并且是生物样本的储存状态的特征 (1)。 本发明还涉及用于冷冻保存样品的监测装置,特别是用于执行所述方法。

    VERFAHREN UND VORRICHTUNG ZUR HERSTELLUNG VON GEFRORENEN BIOLOGISCHEN PARTIKELN
    38.
    发明公开
    VERFAHREN UND VORRICHTUNG ZUR HERSTELLUNG VON GEFRORENEN BIOLOGISCHEN PARTIKELN 有权
    方法和制造装置中冷冻的生物粒子

    公开(公告)号:EP2273871A2

    公开(公告)日:2011-01-19

    申请号:EP09725576.4

    申请日:2009-03-13

    IPC分类号: A01N1/02 B01L3/00

    摘要: The invention relates to a method for producing a plurality of frozen biological particles (1) which are suitable for deposition in biological material. Said method comprises the following steps: making available a liquid suspension having a cellular component (3, 3.1 – 3.10) which comprises at least one of the following: at least one biological cell, at least one cell group and at least one cell component, receiving subportions (2) of the suspension in receiving elements (12) of a carrier device (11), cooling the carrier device (10) and freezing the subportions of the suspension, thereby forming the frozen biological particles (1) having an interior shape and interior size of the receiving elements, and separating the frozen biological particles (1) from the receiving elements (12). The invention also relates to a freezing device (100) which is designed to produce a plurality of frozen biological particles.