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    METHOD FOR PREPARING SURFACE COATING WITH REDUCED DEGRADATION RATE OF BIODEGRADABLE MAGNESIUM ALLOY VASCULAR STENT
    41.
    发明公开
    METHOD FOR PREPARING SURFACE COATING WITH REDUCED DEGRADATION RATE OF BIODEGRADABLE MAGNESIUM ALLOY VASCULAR STENT 审中-公开
    方法用于生产具有血管支架折减降速表面涂层由生物可降解镁合金

    公开(公告)号：EP3144018A1

    公开(公告)日：2017-03-22

    申请号：EP15792801.1

    申请日：2015-04-30

    申请人： Jiangsu Fengyuan Medical Devices Co., Ltd.

    发明人： LIU, Jing ,  WANG, Min ,  ZHANG, Zhixiong ,  XI, Tingfel

    IPC分类号： A61L31/10 ,  A61L31/08

    CPC分类号： A61L31/10 ,  A61L31/022 ,  A61L31/14 ,  A61L2420/02 ,  C08L67/04

    摘要： Disclosed is a method for preparing a surface coating with a reduced degradation rate of a biodegradable magnesium alloy vascular stent, comprising firstly grafting a silane coupling agent to the surface of a magnesium ally by dip coating, heat curing, and forming a silane coupling agent coating on the surface of the magnesium alloy; and then coating a polymer on the surface of the silane coupling agent coating by spin coating, and drying under vacuum to form a polymer coating. The polymer coating on the surface of the magnesium alloy and pretreated by a silane coupling agent can enhance the bonding force with the surface of the magnesium alloy vascular stent to suppress excessive degradation of the magnesium alloy matrix, and improve the biocompatibility of the vascular stent.

    摘要翻译： 公开了一种用于制备表面涂层，可生物降解的镁合金血管支架的降低的降解速率，包括首先通过浸渍涂布，热固化接枝的硅烷偶联剂的镁同盟的表面上，并形成硅烷偶联剂涂层的方法 镁合金的表面上; 然后涂布由旋涂硅烷偶联剂涂层的表面上形成聚合物，并在真空下干燥，以形成聚合物涂层。 镁合金的表面上的聚合物涂层和由硅烷偶联剂预处理可增强与所述镁合金血管支架的表面的结合力来抑制镁合金基质的过度降解，并提高血管支架的生物相容性。

    STABFÖRMIGER KÖRPER UND MEDIZINISCHES INSTRUMENT
    43.
    发明公开
    STABFÖRMIGER KÖRPER UND MEDIZINISCHES INSTRUMENT 审中-公开
    STABFÖRMIGERKÖRPER发明医学仪器

    公开(公告)号：EP3134141A1

    公开(公告)日：2017-03-01

    申请号：EP15735845.8

    申请日：2015-04-23

    申请人： MaRVis Medical GmbH

    发明人： DÜRING, Klaus ,  DLAIKAN-CAMPOS, Nasib ,  VAN DIJK, Maarten

    IPC分类号： A61L31/18

    CPC分类号： A61B90/39 ,  A61B5/055 ,  A61B2090/3954 ,  A61L31/022 ,  A61L31/026 ,  A61L31/10 ,  A61L31/14 ,  A61L31/18 ,  A61M25/0127 ,  A61M25/09 ,  A61M2025/09166 ,  G01R33/287

    摘要： The invention relates to a rod-shaped body comprising a central portion and a peripheral portion, wherein the central portion is arranged in the center of the rod-shaped body and is surrounded by the peripheral portion. Both the central portion and the peripheral portion substantially extend across the entire length of the rod-shaped body. The central portion has at least one non-metallic fiber bundle that is embedded in a non-ferromagnetic matrix material. The matrix material is doped with marker particles. The peripheral portion has at least one undoped, non-ferromagnetic matrix material. The diameter of the central portion is less than or equal to 0.2 mm, preferably less than or equal to 0.15 mm, and even more preferably, is less than or equal to 0.1 mm, and in particular less than or equal to 0.08 mm.

    摘要翻译： 本发明涉及一种包括中心部分和周边部分的杆状体，其中中心部分布置在杆状体的中心并被周边部分包围。 中心部分和周边部分基本上沿棒状体的整个长度延伸。 中心部分包​​括嵌入非铁磁基质材料中的至少一种非金属纤维束。 基质材料掺杂有标记颗粒。 外围部分包括至少一种未掺杂的非铁磁基质材料。 中心部分的直径小于或等于0.2mm，优选小于或等于0.15mm，甚至更优选小于或等于0.1mm，特别是小于或等于0.08mm。

    METHOD FOR PREPARING TITANIUM-CONTAINING IMPLANT BY USING ENVIRONMENTALLY-FRIENDLY ETCHING COMPOSITION
    44.
    发明公开
    METHOD FOR PREPARING TITANIUM-CONTAINING IMPLANT BY USING ENVIRONMENTALLY-FRIENDLY ETCHING COMPOSITION 审中-公开
    METHOD FOR PRODUCING植入物含钛BY利用污染的蚀刻组合物的

    公开(公告)号：EP3124056A1

    公开(公告)日：2017-02-01

    申请号：EP15768577.7

    申请日：2015-03-18

    申请人： Kyungpook National University Industry-Academic Cooperation Foundation

    发明人： KIM, Kyo Han ,  KWON, Tae Yub ,  SON, Jun Sik

    IPC分类号： A61L27/06 ,  A61L27/36

    CPC分类号： C23F1/26 ,  A61L27/06 ,  A61L31/022 ,  A61L31/14 ,  A61L2400/18 ,  C23F1/00

    摘要： The present invention provides a method for preparing an implant including preparing a mixed etching composition including hydrogen peroxide and a water-soluble carbonate compound and oxidatively etching an implant made of titanium or a titanium alloy by immersing the same in the etching composition; a titanium or titanium alloy implant prepared by oxidative etching with a mixed etching composition including hydrogen peroxide and a water-soluble carbonate compound; and a composition for treating surface of an implant containing hydrogen peroxide and a water-soluble carbonate compound. Further, the present invention relates to a titanium or titanium alloy implant which is prepared by oxidative etching with a mixed etching composition including hydrogen peroxide and a basic solution and on which surface bumps having continuous or discontinuous line-shaped open channel structures in nanoscale are irregularly formed, and a preparation method thereof. The surface of the titanium alloys treated with the mixed etching composition including hydrogen peroxide and a carbonate compound or the etching composition containing hydrogen peroxide and a basic solution of the present invention includes micrometer-sized bumps and channel-shaped nanometer-sized bumps, and thus has an increased surface area, and can not only improve wettability, but also effectively promote cell proliferation and osteocyte differentiation. In addition, the composition includes no chemical compounds such as a strong acid, etc. and is thus environmentally friendly, and such compounds can be prevented from remaining on the surface, which can improve biocompatibility, and therefore, the composition can be useful for implant surface treatment.

    摘要翻译： 本发明提供了用于制备植入包括制备混合蚀刻组合物包括过氧化氢和水溶性碳酸酯化合物和氧化蚀刻由钛或通过在蚀刻组合物中浸渍相同钛合金的植入物的方法; 通过氧化蚀刻用混合蚀刻组合物包括过氧化氢和水溶性碳酸酯化合物制备的钛或钛合金植入物; 和用于治疗的植入物含有过氧化氢和水溶性碳酸酯化合物的表面的组合物。 此外，本发明涉及一种钛或钛合金植入物全部是由氧化用混合蚀刻组合物包括过氧化氢和碱性溶液和在具有在纳米级连续或不连续线状开放通道结构，该结构的表面凹凸被不规则地蚀刻制备 形成，并且它们的制备方法。 与混合蚀刻组合物包括过氧化氢和碳酸酯化合物或蚀刻组合物含有过氧化氢和本发明的碱性溶液处理的钛合金的表面包括微米大小的凸起和槽道形纳米尺寸的突起，并由此 具有增加的表面面积，并且不仅可以提高润湿性，从而有效地促进细胞增殖和分化骨细胞但。 此外，该组合物不包含化学化合物：诸如强酸等，因此是环境友好的，并且这样的化合物可以从残留在表面，从而可以提高生物相容性，因此在可以防止，该组合物可以是用于植入物有用 表面处理。

    ORTHOPEDIC FASTENER DEVICE
    45.
    发明公开
    ORTHOPEDIC FASTENER DEVICE 审中-公开
    ORTHOPÄDISCHEBEFESTIGUNGSVORRICHTUNG

    公开(公告)号：EP3116456A1

    公开(公告)日：2017-01-18

    申请号：EP14885327.8

    申请日：2014-03-10

    申请人： Eventions, LLC ,  Mangiardi, Eric K.

    发明人： MANGIARDI, Eric K.

    IPC分类号： A61F5/05 ,  A61F13/10

    CPC分类号： A61L31/022 ,  A61B17/72 ,  A61B2017/00898 ,  A61F13/04 ,  A61L31/042 ,  A61L31/10 ,  A61L31/124 ,  A61L31/148 ,  C08L5/08

    摘要： Orthopedic fastener devices for fixation of fractured bones are disclosed. The orthopedic fastener device is in the form of an orthopedic fastener having an IM nail coated on its external surface with a bioabsorbable or biodegradable hydrogel. Also disclosed are hydrogel coated orthopedic fastener devices in the form of a K-wire or bone screw, a method for stabilizing a fractured long bone fracture by inserting an orthopedic fastener into the medullary canal of the bone and a kit for fastener implantation.

    摘要翻译： 公开了用于固定骨折骨的矫形紧固装置。 整形外科紧固件装置是具有在其外表面上涂覆有生物可吸收或可生物降解的水凝胶的IM钉的矫形紧固件的形式。 还公开了以K线或骨螺钉形式的水凝胶涂覆的整形外科紧固件装置，通过将整形外科紧固件插入骨的髓管来稳定骨折的长骨折断的方法和用于紧固件植入的套件。

    BIODEGRADABLE PURE MAGNESIUM BONE NAIL
    49.
    发明公开
    BIODEGRADABLE PURE MAGNESIUM BONE NAIL 有权
    生物学家ABBAUBARER KNOCHENNAGEL AUS REINEM MAGNESIUM

    公开(公告)号：EP3081181A1

    公开(公告)日：2016-10-19

    申请号：EP14852540.5

    申请日：2014-07-31

    申请人： Dongguan Eontec Co., Ltd.

    发明人： LAO, Yonghua ,  LI, Yangde ,  LI, Weirong ,  LIU, Fangfei

    IPC分类号： A61B17/86

    CPC分类号： A61B17/864 ,  A61B17/866 ,  A61B2017/00004 ,  A61L31/022 ,  A61L31/148

    摘要： A biodegradable pure magnesium bone nail comprises a rod-shaped pure magnesium screw bone nail (1). From the bottom of a crossed groove (4), for turning a screw, of a tip of the screw bone nail (1), an axial hole (2) whose length is 2/3 of that of a rod of the screw bone nail is manufactured. In the length of the axial hole (2) of the screw bone nail (1), several radial holes (3) are uniformly manufactured from the bottom of thread into the axial hole (2) at 90 degrees.

    摘要翻译： 可生物降解的纯镁骨钉包括棒状纯镁螺钉骨钉（1）。 用于转动螺钉骨钉（1）的尖端的交叉凹槽（4）的底部，具有长度为螺钉骨钉棒的2/3的轴向孔（2） 被制造。 在螺钉骨钉（1）的轴向孔（2）的长度上，从颈部的底部均匀地制造出几个径向孔（3），其轴向孔（2）为90度。