公开(公告)号：EP2331189A4

公开(公告)日：2012-05-23

申请号：EP09812331

申请日：2009-09-04

申请人： CARDIOPOLYMERS INC

发明人： SHANNON DON ,  AHMANN FRANK

IPC分类号： A61F2/958 ,  A61M31/00 ,  A61B17/00 ,  A61B17/12 ,  A61B17/70 ,  A61F2/02 ,  A61F5/00 ,  A61L27/14 ,  A61L27/54 ,  A61L31/04 ,  A61L31/14 ,  B29C51/00 ,  B29C61/02

CPC分类号： A61M25/1029 ,  A61B17/7097 ,  A61B2090/3966 ,  A61F2/0059 ,  A61F2/12 ,  A61F5/0036 ,  A61L31/04 ,  A61L31/14 ,  A61L31/146 ,  A61M25/1027 ,  A61M2025/0089 ,  A61M2025/1054

公开(公告)号：EP2427226A2

公开(公告)日：2012-03-14

申请号：EP10772713.3

申请日：2010-05-04

申请人： Beisang, Arthur A. ,  Ersek, Robert A. ,  Beisang Iii, Arthur A. ,  Beisang, Daniel J.

发明人： Beisang, Arthur A. ,  Ersek, Robert A. ,  Beisang Iii, Arthur A. ,  Beisang, Daniel J.

IPC分类号： A61L27/14 ,  A61F2/12 ,  C08F26/10

CPC分类号： A61F2/12 ,  A61L27/16 ,  A61L27/54 ,  C08L39/06

摘要： Compositions of cross-linked polyvinylpyrrolidone (PVP) are disclosed that are generally in the form of an elastic, hydrophilic, water-insoluble viscous cohesive mass of material that has many important medical uses including uses as a filler for implants. The present invention also involves a process for producing such compositions.

公开(公告)号：EP2421550A2

公开(公告)日：2012-02-29

申请号：EP10726699.1

申请日：2010-04-20

申请人： Allergan, Inc.

发明人： ALTMAN, Gregory, H. ,  HORAN, Rebeca, L. ,  COLLETTE, Adam, L. ,  CHEN, Jing, Song

IPC分类号： A61K38/17

CPC分类号： A61F2/12 ,  A61K8/64 ,  A61K38/1767 ,  A61K47/42 ,  A61K2800/5922 ,  A61K2800/91 ,  A61L27/227 ,  A61L27/26 ,  A61L27/52 ,  A61L2430/34 ,  A61Q19/00 ,  C08B37/0072 ,  C08L89/00

摘要： The present specification provides for methods for purifying fibroins, purified fibroins, methods of conjugating biological and synthetic molecules to fibroins, fibroins conjugated to such molecules, methods of making fibroin hydrogels, fibroin hydrogels and fibroin hydrogel formulations useful for a variety of medical uses, including, without limitation uses as bulking agents, tissue space fillers, templates for tissue reconstruction or regeneration, cell culture scaffolds for tissue engineering and for disease models, surface coating to improve medical device function, or drug delivery devices.

公开(公告)号：EP2068766B1

公开(公告)日：2011-10-19

申请号：EP07813589.4

申请日：2007-07-31

申请人： Organogenesis, Inc.

发明人： HAMMOND, Dennis C. ,  CODORI-HURFF, Jeanne M.

IPC分类号： A61F2/12 ,  A61K35/38

CPC分类号： A61F2/12 ,  A61F2/0063 ,  A61F2210/0004

摘要： Mastopexy and breast reconstruction prostheses and implantation method that allow for radiographic imaging of the breast tissue. The prostheses are arcuate and elongate optionally meshed to conform with breast tissue when implanted. Prostheses are made from naturally occurring extracellular matrix, primarily collagen, that, allows for mammographic imaging without interference as is expected from synthetic materials.

公开(公告)号：EP2349051A1

公开(公告)日：2011-08-03

申请号：EP09791657.1

申请日：2009-08-19

申请人： Allergan, Inc.

发明人： SCHUESSLER, David, J.

IPC分类号： A61B19/00 ,  A61F2/12 ,  A61F5/00 ,  A61F2/02 ,  A61F2/00

CPC分类号： B29C73/20 ,  A61B90/02 ,  A61F2/12 ,  A61F5/003 ,  A61F5/0036 ,  A61F2210/0061 ,  A61F2250/0003 ,  B29C41/003 ,  B29C41/06 ,  B29C73/16 ,  B29C73/163 ,  B29C73/18 ,  B29C73/22 ,  B29K2083/00 ,  B29K2995/0062 ,  B29L2031/7532

摘要： A self-sealing shell (22) useful as a component of a soft fluid-filled prosthetic implant is provided. The shell is at least partly constructed of a wall (28) made of a colloid of an elastomeric polymer matrix (32) and particles (34) of a water-swellable material distributed therein.

摘要翻译： 提供了可用作软性流体填充的假体植入物的组件的自密封壳体（22）。 外壳至少部分地由由弹性体聚合物基体（32）的胶体和分布在其中的水溶胀性材料的颗粒（34）制成的壁（28）构成。

公开(公告)号：EP1429685B1

公开(公告)日：2011-07-13

申请号：EP02748180.3

申请日：2002-07-17

申请人： ALLERGAN, INC.

发明人： SCHUESSLER, David, J.

IPC分类号： A61F2/06 ,  B29C41/06 ,  A61F2/12

CPC分类号： B29C41/06 ,  A61B17/12099 ,  A61B17/12109 ,  A61B17/12136 ,  A61B2017/00526 ,  A61B2017/00557 ,  A61F2/12 ,  A61F2002/3007 ,  A61F2240/004 ,  A61M25/1029 ,  B29C33/0038 ,  B29C33/58 ,  B29C33/68 ,  B29C41/003 ,  B29C41/38 ,  B29C41/42 ,  B29C41/50 ,  B29C2791/006 ,  B29K2083/00 ,  B29L2031/753 ,  Y10S425/06 ,  Y10S425/812 ,  Y10T428/1376

摘要： A system and method for molding the shell of a medical device or other molded article is disclosed. The system includes a multi-axis rotational molding machine (50) in which a mold (100) is mounted. The mold (100) has a cavity (60) in the shape of the article to be molded. The mold (100) seals to hold a vacuum. In operation, silicone or other molding material is inserted into the mold (100), vacuum is applied to the mold (100), the mold (100) is rotated about at least two axes (A, B) and a molding material coats the inside walls of the mold (100) to form the shell or other desired article. A rotationally molded medical article is also disclosed.

公开(公告)号：EP2326336A1

公开(公告)日：2011-06-01

申请号：EP09803207.1

申请日：2009-07-30

申请人： Mesynthes Limited

发明人： JOHNSON, Keryn Dallas ,  MAY, Barnaby Charles Hough ,  WARD, Brian Roderick

IPC分类号： A61K35/38 ,  A61F2/02 ,  A01N1/02 ,  A61L27/40

CPC分类号： A61K35/38 ,  A61F2/0059 ,  A61F2/12 ,  A61K31/65 ,  A61L27/3633 ,  A61L27/3839 ,  A61L27/54 ,  A61L2300/252 ,  A61L2300/406 ,  A61L2300/414 ,  A61L2300/45 ,  C12N1/00 ,  C12N2320/00 ,  C12N2533/00 ,  C12N2533/90

摘要： The present invention pertains to the development of Extracellular Matrix (ECM) scaffolds derived from the forestomach of a ruminant. Such scaffolds are useful in many clinical and therapeutic applications, including wound repair, tissue regeneration, and breast reconstruction. In addition, the present invention features methods of isolating ECM scaffolds from mammalian organs, including but not limited to the ruminant forestomach. The invention further features laminated ECM scaffolds containing a polymer positioned between individual ECM sheets. The polymer may optionally contain bioactive molecules to enhance the functionality of the scaffold.

公开(公告)号：EP2287508A2

公开(公告)日：2011-02-23

申请号：EP10183386.1

申请日：2000-04-14

申请人： ALLERGAN, INC.

发明人： Schuessler, David J.

IPC分类号： F16L21/00

CPC分类号： A61F2/12 ,  A61B17/1322 ,  A61B90/02 ,  A61B2017/00557 ,  A61F2220/0008 ,  F16L27/04 ,  Y10S604/905

摘要： A universal implant connector (200) for coupling a fill tubing (6) to an implant (9) is disclosed. A barb (4), or other leakproof fill tube connection, couples to the fill tubing (6) and a fill tip (16) couples to the implant (9). The barb (4) and the fill tip (16) each have a passage therethrough, and each of these passages have an axis. A joint connects the barb (4) to the fill tip (16) so that the barb (4) may rotate from a position where the barb axis is approximately parallel to the fill tip axis to a position where the barb axis is approximately perpendicular to the fill tip axis. Another form of the disclosed connector includes a joint that connects the barb (4) to the fill tip (16) so that the barb (4) may rotate approximately 360 degrees about the fill tip axis.

摘要翻译： 公开了一种用于将填充管（6）联接到植入物（9）的通用植入物连接器（200）。 倒钩（4）或其他防漏填充管连接件连接到填充管（6），并且填充尖端（16）联接到植入物（9）。 倒钩（4）和填充尖端（16）各自具有穿过其中的通道，并且这些通道中的每一个都具有轴线。 接头将倒钩（4）连接到填充尖端（16），使得倒钩（4）可以从倒钩轴线近似平行于填充尖端轴线的位置旋转到倒钩轴线近似垂直于 填充尖端轴。 所公开的连接器的另一种形式包括将倒钩（4）连接到填充尖端（16）的接头，使得倒钩（4）可围绕填充尖端轴线旋转约360度。

公开(公告)号：EP2286761A1

公开(公告)日：2011-02-23

申请号：EP10181933.2

申请日：2006-10-25

申请人： ALLERGAN, INC.

发明人： Maxwell, Patrick G. ,  Powell, Thomas E. ,  Carlisle, Daniel A.

IPC分类号： A61F2/12

CPC分类号： A61F2/12

摘要： A variable cohesive gel form stabilizing implant is disclosed for augmentation or reconstruction of the breast. The prosthesis of this invention comprises an implantable shell or envelope (not limited to a single shell or envelope), filled with a biocompatible gel, or gels, having alterations in gel cohesiveness to maintain stable form, shape, and dimension after surgical implantation. The gel cohesiveness may increase, with increased volume or dimension of the prosthesis. The variable cohesiveness of the gel filler material may be altered by any means (i.e. chemical, fabrication, etc.). The variable cohesive gel form stabilizing implant has shape retention characteristics to maintain its form, thereby reducing or eliminating the undesirable effects of shell wrinkling, knuckling, scalloping or deformation, which can occur at the upper or lower pole of the prostheses, along the perimeter of the shell or at the base, post-implantation. Finally, the variable cohesive gel form stabilizing implant provides new control and possibilities for achieving and preserving the most natural breast shape.

摘要翻译： 公开了用于乳房增大或重建的可变内聚凝胶形式的稳定植入物。 本发明的假体包括可植入的外壳或外壳（不限于单个外壳或外壳），填充有生物相容性凝胶或凝胶，其具有凝胶粘结性的改变以在手术植入后保持稳定的形状，形状和尺寸。 随着假体的体积或尺寸的增加，凝胶粘结性可能增加。 凝胶填充材料的可变粘合性可以通过任何方式（即化学，制造等）改变。 可变内聚凝胶形式稳定植入物具有保持其形状的形状保持特性，从而减少或消除可能在假体的上极或下极处发生的外壳起皱，指关节，扇形或变形的不期望的影响，沿着 外壳或底座，植入后。 最后，可变凝聚凝胶形式稳定植入物为实现和保持最自然的乳房形状提供了新的控制和可能性。

公开(公告)号：EP2247260A1

公开(公告)日：2010-11-10

申请号：EP09705732.7

申请日：2009-01-30

申请人： Milux Holding SA

发明人： FORSELL, Peter

IPC分类号： A61F2/12

CPC分类号： A61F2/12 ,  A61F2250/0004

摘要： A breast implant system is provided comprising a plurality of chambers including one or more first fluid chambers (1 ) and one or more second fluid chambers (2). The first fluid chamber (1 ) forms part of a breast implant (10), whereas the second fluid chamber (2) may also form part of the breast implant or may be implanted remote from the breast implant. The first and second fluid chambers are interconnected so as to allow exchange of fluid between the first and second chambers, thereby causing the shape and, depending upon the specific embodiment, also the volume to change accordingly.