Abstract:
A gas sensor comprises a cavity (32) for containing a gas, means (16) for generating radiation which is transmitted through the cavity and includes one or more wavelengths which is absorbed in use by a gas to be detected; and a detector (14) for detecting radiation which has passed through the cavity (32). The walls of the cavity (32) are sufficiently reflective to the radiation that the cavity (32) is substantially uniformally illuminated with the radiation.
Abstract:
Described and claimed is an interchangeable tip-open cell fluorometer comprising a housing and a fluorometric probe tip interchangeably connected to the housing, the probe tip including a probe tip housing defining an open cell and enclosing a probe optical arrangement, the probe optical arrangement including an excitation source and a fluorescence detector wherein the excitation source is aimed directly into the fluorescence detector such that a sample can be fluorometrically detected. Also claimed is a method of using this interchangeable tip-open cell fluorometer for detecting fluorescent signals emitted by one or more fluorophores from samples from a natural or industrial water system. The fluorometer, when coupled with a controller, is capable of monitoring and optionally controlling an industrial process or system.
Abstract:
The invention relates to devices and methods for detecting specific interactions between probe and target molecules. The invention especially relates to a device for the qualitative and/or quantitative detection of molecular interactions between probe and target molecules, which comprises a) a microarray comprising a substrate on which probe molecules are immobilized on array elements, said microarray being located on a first surface of the device; and b) a reaction chamber that is defined between the first area with the microarray disposed thereon and a second surface, the distance between the microarray and the second surface being modifiable.
Abstract:
The invention provides for an optical measuring instrument and measuring device. The optical measuring instrument for investigating a specimen contained in a sample comprises at least one source for providing at least one electromagnetic beam intended to irradiate the sample and to interact with the specimen within the sample, at least one sensor for detecting an output of the interaction between the specimen and the electromagnetic beam, an integrally formed mechanical bench for the optical and electronic components, a sample holder for holding the sample, wherein the at least one source, the at least one sensor, and the mechanical bench are integrated in one monolithic optoelectronic module and the sample holder can be connected to this module.
Abstract:
A cartridge (10, 60, 80, 110, 130, 140, 170, 180, 200, 222, 224, 226, 228, 230, 240, 242, 246, 280, 282, 300) and cartridge system (220) for use in an apparatus (12) for analyzing a sample (16) is provided. The cartridge has one or more light sources (18) and/or optical systems (22, 34, 84, 120, 162) and other components that are specific for a certain type of application such as fluorescence, absorbance, or luminescence. The light source, optical systems, and other components for a specific application are housed in a single cartridge. The system has a plurality of cartridges for different applications for a multimode instrument. The cartridges are removably engaged with the apparatus in a 'plug-in' format such that one cartridge may be removed from the apparatus and another cartridge may be easily installed.
Abstract:
The invention relates to an arrangement for continuous determination of a substance comprising a chemically reacting sensor element (21) arranged in or adjacent to a limiting wall of a volume (22) containing the substance, where in a housing (2) of a modular device (1) optical elements to read the sensor element (21) are arranged, comprising at least one light source (35) illuminating the sensor element (21) and at least one sample detector (29) detecting the light scattered by the sensor element (21), and where a front side of the housing (2) comprises a coupling for the sensor element (21), so that the sensor element (21) may be interchangeably and modularly coupled to the front side of the housing (2). A glass body (24) is arranged adjacent to the coupling for direct contact with the sensor element (21) and separate conduits (34, 31) for the illuminating and for the scattered light are arranged rearward of the glass body (24). The modular device (1) allows for easily interchanging the modular sensor element (21) and provides an optical connection between the sensor element (21) and the detector (29) which is steady and allows for high quality measurements.
Abstract:
A multimode waveguide device for assays includes a multimode waveguide with a patterned, reflective surface coating. The exposed portion or portions of the reflectively coated waveguide surface are for analyte recognition. A fluidics cell is attached to the waveguide so that the channel or channels of the fluidics cell match with the exposed portion or portions of the waveguide surface. The channel or channels direct one or more sample fluids over the exposed portion or portions of the waveguide surface. The reflective coating minimizes loss and scattering of excitation and fluorescence light during a fluorescence assay.
Abstract:
The invention relates to a system for the spectrometric determination of a chemical and/or physical process variable of a measuring medium (29), comprising a process probe (2; 3, 4, 5, 6), a spectrometric module (9; 10, 11, 12, 13) and an evaluation module (19), whereby various process probes (2; 3, 4, 5, 6) can be used together with the system. The respective process probe (2; 3, 4, 5, 6) used is associated with a probe-specific spectrometric module (9; 10, 11, 12, 13) matched for the respective process probe (2; 3, 4, 5, 6). The probe-specific spectrometric module (9; 10, 11, 12, 13) is adapted to provide spectral measuring signals from which the evaluation module (19) determines the process variable by means of a substantially uniform evaluation algorithm.
Abstract:
An optical system made up of lens arrays (2i, 7) and normal lenses (41, 5, 42) is particularly suitable for use as a massive parallel reader (approx. 102 channels) for micro titer plates (1) and the like in absorption, fluorescence and luminescence.
Abstract:
Described and claimed is a modular fluorometer and a method of using same to control an industrial water system, wherein said modular fluorometer comprises: one or more units with each unit comprising: a channel comprising an optically appropriate cell through which a water sample flows; a light source positioned outside said optically appropriate cell; an optional excitation filter positioned between the light source and the optically appropriate cell; a reference detector positioned outside the optically appropriate cell; an emission detector positioned outside the optically appropriate cell; an optional emission filter positioned between said emission detector and said optically appropriate cell; wherein if more than one unit is present in said modular fluorometer, said optically appropriate cells through which said water sample flows are aligned such that only one channel through which a water sample flows exists in said fluorometer.