公开(公告)号：EP1678507A1

公开(公告)日：2006-07-12

申请号：EP04781418.1

申请日：2004-08-17

申请人： Biomerieux, Inc.

发明人： BLANTON, Ross, Mitchell ,  JUSTIN, Michael, James ,  BISHOP, James, Clement ,  YAM, Jacky, S. ,  POLSTER, Robert, J. ,  FANNING, Mark, Joseph

IPC分类号： G01N35/00

CPC分类号： G01N35/00029 ,  G01N2035/00148 ,  G01N2035/0465 ,  Y10T436/115831 ,  Y10T436/12

摘要： An integrated instrument processes fluid test samples using disposable test devices. The test devices are carried in a carrier. The instrument includes a vacuum station receiving the carrier for batch loading of the test devices with fluid samples to be tested. The user removes the carrier from the vacuum station and inserts it into a loading station of a separate carrier and test device processing subsystem. This subsystem includes a transport system moving the carrier through the instrument where various modules perform operations on the test devices, including sealing the test devices, loading the test devices into an incubation station, incubation of the test devices, test device reading, and test device disposal.

公开(公告)号：EP1622506A2

公开(公告)日：2006-02-08

申请号：EP04760362.6

申请日：2004-04-22

申请人： Tyco Healthcare Group LP ,  Biomerieux, Inc.

发明人： SAMPSON, Eric ,  RONSICK, Christopher, S.

IPC分类号： A61B5/00

CPC分类号： A61J1/2096 ,  A61B5/15003 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150992 ,  A61B5/154 ,  A61B5/155 ,  A61J1/2055 ,  A61J1/2065 ,  Y10S604/905

摘要： A transfer needle safety apparatus (10) including a guide port adapted to fit a variety of body fluid receptacle sizes. A sleeve (30) substantially fills the cavity inside a needle shield.

公开(公告)号：EP1473370A2

公开(公告)日：2004-11-03

申请号：EP04252422.3

申请日：2004-04-26

申请人： BioMerieux, Inc.

发明人： Chatellier, Sonia ,  Lacroix, Bruno ,  Zeng, Qiandong ,  Childress, Darrell ,  Moir, Donald T.

IPC分类号： C12Q1/68

CPC分类号： G06F19/22 ,  C12Q1/6837 ,  C12Q1/686 ,  C12Q1/689

摘要： Materials and methods for identifying unique sites in bacterial 16S and 23S rDNA are provided, as well as specific unique sequences of 16S rDNA in select bacteria. The distinguishing moieties will enable rapid differentiation between families, genera, groups, species, strains, subspecies, and isolates of microorganisms. Such differentiation can be performed by using rapid screening kits in combination with in silico analysis for diagnostic, prognastic, epidemiologic, phylogenetic, and other purposes.

摘要翻译： 提供了用于识别细菌16S和23S rDNA中独特位点的材料和方法，以及选择性细菌中16S rDNA的特异性独特序列。 区别部分将使家庭，属，群体，物种，菌株，亚种和微生物分离物之间能够快速分化。 这种分化可以通过使用快速筛选试剂盒与用于诊断，预后，流行病学，系统发育和其它目的的计算机分析相结合来进行。

公开(公告)号：EP1337660A2

公开(公告)日：2003-08-27

申请号：EP01983170.0

申请日：2001-10-18

申请人： BioMerieux, Inc.

发明人： TEJIDOR, Liliana ,  FISCHER, Timothy, J. ,  BAGLIN, Trevor

IPC分类号： C12Q1/56 ,  C12Q1/00

CPC分类号： G01N33/86

摘要： A method is disclosed for determining if a patient is hypercoagulable, hypocoagulable or normal. The test involves providing a test sample from the patient and initiating coagulation in the sample in the presence of an activator, which is added to the sample in an amount which will result in intrinsic tenase-dependent fibrin. Then the formation of the intrinsic tenase-dependent fibrin polymerization is monitored over time so as to derive a time-dependent profile, with the results of the fibrin polymerization monitoring determining whether the patient is hypercoagulable, normal or hypocoagulable. The coagulation activator is added in an amount that triggers a thrombin explosion that is dependent on the propagation phase and amplification pathways. In this way, a single assay can assess the hemostatic potential of a sample.

公开(公告)号：EP1252191A1

公开(公告)日：2002-10-30

申请号：EP00978502.3

申请日：2000-11-10

申请人： BioMerieux, Inc.

发明人： SARNGADHARAN, Mangalasseril, G. ,  PAL, Ranajit ,  DEVICO, Anthony, L.

IPC分类号： C07K16/44 ,  G01N33/53 ,  C12N15/11 ,  C12Q1/68

CPC分类号： C07K16/44 ,  Y10S530/809

摘要： The present invention is directed to the discovery of antibodies that will react to proteins or nucleic acids bound to particular suberic acid crosslinkers, but not to the free crosslinkers or free proteins or nucleic acids. Monoclonal antibodies with such binding specificity have widespread applications in receptor-ligand binding, immunodiagnostic and nucleic acid diagnostics.

公开(公告)号：EP1146963A1

公开(公告)日：2001-10-24

申请号：EP00968466.3

申请日：2000-09-29

申请人： Biomerieux, Inc.

发明人： KLUTTZ, Brian ,  McKINLEY, Geoff, A. ,  GENNARI, Fabio ,  GUY, Michel ,  COTTER, Christopher ,  CATANZARITI, Luigi ,  GRAZIANO, Louis ,  COLIN, Bruno ,  PARIS, Cécile ,  DACHAUD, Jacques

IPC分类号： B01L7/00 ,  B01L3/00

CPC分类号： C12Q1/6848 ,  B01L3/502 ,  B01L7/52 ,  B01L7/525 ,  B01L2200/026 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/0809 ,  B01L2300/0825 ,  B01L2300/0861 ,  B01L2300/087 ,  B01L2300/1822 ,  B01L2400/0487 ,  B01L2400/049 ,  B01L2400/0633 ,  B01L2400/0644 ,  B01L2400/0655 ,  G01N35/026 ,  G01N2035/0436

摘要： An instrument for conducting nucleic acid amplification reactions in a disposable test device. The test device includes a first reaction chamber containing a first nucleic acid amplification reagent (e.g., primers and nucleotides) and a second reaction chamber either containing, or in fluid communication, with a second nucleic acid amplification reagent (e.g., an amplification enzyme such as RT). The instrument includes a support structure receiving the test device. A temperature control system maintains the first reaction chamber at a first elevated temperature but simultaneously maintains the second nucleic acid amplification reagent at a second temperature lower than the first temperature so as to preserve the second nucleic acid amplification reagent. An actuator operates on a fluid conduit in the test device to place the first and second reaction chambers in fluid communication with each other after a reaction has occurred in the first reaction chamber at the first temperature. A pneumatic system is also provided that assists in fluid transfer of a reaction solution from the first chamber to the second chamber.

公开(公告)号：EP2352992B1

公开(公告)日：2020-04-22

申请号：EP09752013.4

申请日：2009-10-30

申请人： bioMerieux, Inc.

发明人： WALSH, John ,  HYMAN, Jones ,  THORPE, Thurman ,  CLAY, Bradford ,  RONSICK, Christopher

IPC分类号： G01N21/65 ,  C12M1/12 ,  C12M1/34 ,  G01N21/64 ,  G01N21/359 ,  G01N33/68 ,  G01N21/3581 ,  G01N21/35 ,  C12Q1/04 ,  G01N21/47

公开(公告)号：EP2364218B1

公开(公告)日：2020-04-15

申请号：EP09760034.0

申请日：2009-10-30

申请人： Biomerieux, Inc

发明人： WALSH, John ,  HYMAN, Jones ,  RONSICK, Christopher ,  LINK, John ,  ROBINSON, Ron ,  WILSON, Mark

IPC分类号： G01N21/03 ,  G01N21/35 ,  G01N21/3581 ,  G01N21/359 ,  G01N21/47 ,  G01N21/64 ,  G01N21/65 ,  C12Q1/04 ,  G01N33/68

公开(公告)号：EP3612817A1

公开(公告)日：2020-02-26

申请号：EP18723238.4

申请日：2018-04-20

申请人： Biomerieux, Inc

发明人： YAM, Jacky S. ,  STAMM, Perry D. ,  HARRISON, Joel Patrick ,  MAES, Gregory R. ,  PRICE, Jeffrey Edward ,  HOFFMANN JR., Jack R. ,  KORTE, John Kenneth ,  PINGEL, Daniel Joseph ,  CLYNES, Walter J. ,  FURMAN, Sean Gregory ,  SCHLEICHER JR., Leonard H. ,  KOCHER, Christopher George ,  PETERSON, Brian David

IPC分类号： G01N21/51 ,  G01N21/47

公开(公告)号：EP3612815A1

公开(公告)日：2020-02-26

申请号：EP18724031.2

申请日：2018-04-20

申请人： Biomerieux, Inc

发明人： YAM, Jacky S. ,  MAES, Gregory R. ,  PRICE, Jeffrey Edward ,  HOFFMANN, JR., Jack R. ,  KOCHER, Christopher George ,  BULLOCK, Jared Ian ,  CRANDALL, Samuel B. ,  CLYNES, Walter J.

IPC分类号： G01N21/47 ,  G01N21/59 ,  G01N21/15