公开(公告)号：EP2685178A1

公开(公告)日：2014-01-15

申请号：EP13174532.5

申请日：2005-08-31

申请人： TOKYO INSTITUTE OF TECHNOLOGY

发明人： Tamaura, Yutaka ,  Yoshizawa, Yoshio ,  Utamura, Motoaki ,  Hasuike, Hiroshi ,  Ishihara, Hideyuki ,  Takamatsu, Tadahiko

IPC分类号： F24J2/18 ,  F24J2/24 ,  F24J2/07 ,  F24J2/23

CPC分类号： F03G6/00 ,  F02C1/05 ,  F03G6/064 ,  F05D2240/40 ,  F05D2250/25 ,  F24S10/60 ,  F24S10/70 ,  F24S20/20 ,  F24S23/79 ,  Y02E10/41 ,  Y02E10/44 ,  Y02E10/46

摘要： A sunlight collecting reflector comprises a plurality of first reflectors (12) on which a sunlight is reflected towards an upper light collecting point; and a reflector group (11) constituted by a plurality of reflector segments (21-26) on which the reflected sunlight on the plurality of first reflectors is reflected to a lower light collecting point in a heat collector (13), wherein each of the plurality of the reflector segments (21-26) has reflecting surfaces (21a-26a) which make the sunlight converge on the lower light collecting point, and the reflecting surfaces (21a-26a) of the reflector segments (21-26) comprised in the reflector group (11) are arranged along quadrics of revolution whose confocus is located at the lower light collecting point of the sunlight and whose curvature radiuses are different.

摘要翻译： 阳光收集反射器包括多个第一反射器（12），太阳光朝向上部光收集点反射到其上; 以及由多个反射器部分（21-26）构成的反射器组（11），多个第一反射器上的反射太阳光反射到集热器（13）中的下部聚光点，其中， 多个反射器部分（21-26）具有使太阳光聚光在下部聚光点上的反射面（21a〜26a），反射器部（21-26）的反射面（21a〜26a） 反射器组（11）沿着焦点位于太阳光的下部聚光点并且其曲率半径不同的四次旋转布置。

公开(公告)号：EP2650842A1

公开(公告)日：2013-10-16

申请号：EP11846856.0

申请日：2011-11-17

申请人： NEC Soft, Ltd. ,  Tokyo Institute of Technology

发明人： UEKI Kazuya ,  IHARA Yasuyuki ,  SUGIYAMA Masashi

IPC分类号： G06T7/00 ,  G06N3/00

CPC分类号： G06N5/02 ,  G06K9/00288 ,  G06K9/6278 ,  G06K9/6292 ,  G06K2009/00322 ,  G06N3/0427 ,  G06N7/005 ,  G06Q30/02

摘要： The present invention provides an attribute value estimation device capable of yielding highly accurate estimation results even when people from multiple races are estimation targets. The attribute value estimation device for estimating, from data input thereto, an attribute value of the data includes: a data acquisition unit (1) that acquires data for which an attribute value is to be estimated; a discrete quantity estimation unit (2) that estimates the attribute value as a discrete quantity based on the data acquired by the data acquisition unit (1) and in accordance with a previously learned determination criterion; a first LSPC (3) that estimates the attribute value as a discrete quantity based on data input from the discrete quantity estimation unit (2); and an integration unit (4) that integrates a first discrete quantity estimation value estimated by the discrete quantity estimation unit (2) and a second discrete quantity estimation value estimated by the first LSPC (3).

摘要翻译： 本发明提供一种属性值估计装置，即使来自多个种族的人是估计目标，也能够产生高精度的估计结果。 用于从其输入的数据中估计数据的属性值的属性值估计装置包括：数据获取单元（1），获取要估计属性值的数据; 离散量估计单元（2），其基于由数据获取单元（1）获取的数据并根据先前学习的确定标准来估计属性值作为离散量; 第一LSPC（3），其基于从所述离散量估计单元（2）输入的数据来估计所述属性值作为离散量; 以及积分单元（4），其积分由离散量估计单元（2）估计的第一离散量估计值和由第一LSPC（3）估计的第二离散量估计值。

公开(公告)号：EP2644605A1

公开(公告)日：2013-10-02

申请号：EP11843767.2

申请日：2011-11-16

申请人： Tokyo Institute of Technology ,  Central Glass Company, Limited

发明人： MIKAMI, Koichi ,  AIKAWA, Kohsuke ,  HIOKI, Yuta

IPC分类号： C07D305/10 ,  C07B61/00 ,  C07D407/04 ,  C07D409/04

CPC分类号： C07D305/10 ,  C07D407/04 ,  C07D409/04

摘要： [Problem] To provide a practical production method by which an optically active fluorine-containing oxeten which can become an important intermediate for pharmaceuticals and agrochemicals is able to be stably isolated.
[Solution] This method for producing an optically active fluorine-containing oxeten is characterized in that a fluorine-containing α-ketoester and an internal alkyne are caused to react with each other in the presence of a transition metal complex that has an optically active ligand.
By adopting the production method of the present invention, an optically active fluorine-containing oxeten can be obtained with high regioselectivity and high stereoselectivity (high optical purity) with high yield even in cases where the amount of an asymmetric catalyst is relatively low. In addition, the thus-obtained optically active fluorine-containing oxeten can be converted into various useful intermediates.

摘要翻译： [问题]提供一种实用的制造方法，通过该方法可以稳定地分离成为药物和农药的重要中间体的光学活性的含氟氧杂环丁酮。 [解决方案]制造光学活性的含氟氧杂环丁酮的方法的特征在于，在具有光学活性配体的过渡金属络合物的存在下，使含氟的± - 酮酯和内酯进行反应 。 通过采用本发明的制造方法，即使在非对称催化剂的量相对较少的情况下，也可以以高产率获得具有高的区域选择性和高立体选择性（高光学纯度）的光学活性的含氟氧杂环丁酮。 此外，由此获得的光学活性的含氟氧杂环丁酮可以转化成各种有用的中间体。

公开(公告)号：EP2403804B1

公开(公告)日：2013-09-11

申请号：EP10709185.2

申请日：2010-03-03

申请人： BASF SE ,  Tokyo Institute of Technology

发明人： YILMAZ, Bilge ,  MÜLLER, Ulrich ,  PFAFF, Meike ,  GIES, Hermann ,  XIAO, Feng-Shou ,  TATSUMI, Takashi ,  DE VOS, Dirk ,  BAO, Xinhe ,  ZHANG, Weiping

IPC分类号： C01B33/38 ,  C01B37/00 ,  C01B37/02 ,  B01J20/10 ,  B01J20/30 ,  B01J21/16 ,  C01B33/20 ,  C01B39/02 ,  C01B39/04

CPC分类号： C01B33/20 ,  B01J20/10 ,  B01J20/30 ,  B01J21/16 ,  B01J29/049 ,  C01B33/38 ,  C01B37/00 ,  C01B37/02 ,  C01B39/02 ,  C01B39/04

公开(公告)号：EP2628777A1

公开(公告)日：2013-08-21

申请号：EP11832571.1

申请日：2011-10-12

申请人： Tokyo Institute of Technology

发明人： MURAKAMI, Yoichi ,  SATOH, Isao

IPC分类号： C09K11/06 ,  H01L31/052

CPC分类号： G02B1/04 ,  B01J31/22 ,  C09K11/025 ,  C09K11/06 ,  H01B1/122 ,  H01G9/2013 ,  H01L31/055 ,  Y02E10/52 ,  Y02E10/542 ,  Y02P70/521

摘要： To provide a light conversion element which has solved the problems of the reduced intensity of upconverted light, etc., due to the flammability, volatility or high viscosity of a medium used in the conventional photon upconversion elements.
A light conversion element is provided which has solved the above problems by using a visually homogeneous and transparent light conversion element, wherein organic photosensitizing molecules and organic light-emitting molecules, which are a combination that exhibits a triplet-triplet annihilation process, are dissolved and/or dispersed in an ionic liquid.

公开(公告)号：EP2612678A1

公开(公告)日：2013-07-10

申请号：EP11821972.4

申请日：2011-09-02

申请人： Tokyo Institute of Technology

发明人： IMAI, Takeshi ,  HANDA, Hiroshi

IPC分类号： A61K38/45 ,  A01K67/027 ,  A61K48/00 ,  A61P3/10 ,  C12N5/10 ,  C12Q1/02 ,  G01N33/15 ,  G01N33/50

CPC分类号： C07K14/4703 ,  A01K67/0275 ,  A01K2217/052 ,  A01K2227/105 ,  A01K2267/0362 ,  A61K38/16 ,  A61K38/45 ,  G01N2500/00 ,  G01N2800/042

摘要： It is an object of the present invention to provide a newly identified insulin secretion regulation factor that can control blood sugar in the normal range, and a method for screening an antidiabetic drug using said factor.
In accordance with the present invention, there is provided a composition which is (i) a protein comprising an amino acid sequence represented by SEQ ID NO: 2 or SEQ ID NO: 4; or (ii) a protein comprising an amino acid sequence in which one or several amino acids are deleted, substituted or added in an amino acid sequence represented by SEQ ID NO: 2 or SEQ ID NO: 4 and negatively regulating insulin secretion, as well as a method for screening antidiabetic drug using said protein or a nucleic acid encoding the same.

摘要翻译： 本发明的目的是提供一种能够控制正常范围内的血糖的新鉴定的胰岛素分泌调节因子，以及使用所述因子筛选抗糖尿病药物的方法。 根据本发明，提供了一种组合物，其是（i）包含由SEQ ID NO：2或SEQ ID NO：4表示的氨基酸序列的蛋白质; 或（ii）包含氨基酸序列的蛋白质，其中一个或几个氨基酸被缺失，取代或添加在由SEQ ID NO：2或SEQ ID NO：4表示的氨基酸序列中并且负调节胰岛素分泌 作为使用所述蛋白质或其编码的核酸筛选抗糖尿病药物的方法。

公开(公告)号：EP2588413A1

公开(公告)日：2013-05-08

申请号：EP11800291.4

申请日：2011-07-01

申请人： BASF SE ,  Tokyo Institute of Technology

发明人： YILMAZ, Bilge ,  MÜLLER, Ulrich ,  DE BAERDEMAEKER, Trees ,  GIES, Hermann ,  XIAO, Feng-Shou ,  TATSUMI, Takashi ,  BAO, Xinhe ,  ZHANG, Weiping ,  DE VOS, Dirk

IPC分类号： C01B33/20 ,  C01B39/02 ,  B01J29/04

CPC分类号： B01J29/049 ,  C01B33/20 ,  C01B37/005 ,  C01B39/026 ,  C01B39/48 ,  C07C2/84 ,  C07C2523/28 ,  C07C2523/72 ,  C07C2523/755 ,  C07C2523/883 ,  C07C2523/885

摘要： The present invention relates to a pillared silicate compound comprising a layered silicate structure, and bridging metal atoms located between adjacent silicate layers of the silicate structure, wherein said bridging metal atoms form at least one covalent bond to each of the adjacent silicate layers, as well as a process for the preparation of a pillared silicate compound, and further includes a pillared silicate compound obtainable and or obtained according to said process, as well as a method of catalyzing a chemical reaction comprising the step of contacting one or more chemical compounds with the any of the aforementioned pillared silicate compounds.

公开(公告)号：EP2583693A1

公开(公告)日：2013-04-24

申请号：EP11798001.1

申请日：2011-06-13

申请人： Tokyo Institute of Technology

发明人： IMAI, Takeshi ,  HANDA, Hiroshi

IPC分类号： A61K48/00 ,  A01K67/027 ,  A61K35/76 ,  A61P3/10 ,  A61P43/00 ,  C12N5/10 ,  C12N15/00 ,  C12N15/09 ,  C12Q1/02 ,  C12Q1/48

CPC分类号： C12N15/85 ,  A01K67/0275 ,  A01K2217/052 ,  A01K2227/105 ,  A01K2267/0362 ,  A61K38/45 ,  A61K48/005 ,  C12N9/1051 ,  G01N33/507 ,  G01N2333/91102

摘要： Disclosed are a pharmaceutical composition, a screening method, and the like which use UDP-glucose glycoprotein glycosyl transferase 1 (UGGT1) or a gene encoding the same. UGGT1 has an extremely high proliferative activity compared to known pancreatic β-cell proliferation factors; thus, UGGT1 can act as a useful therapeutic agent for diabetes without any modification and is also useful as a target substance for the development of a new therapeutic agent for diabetes.

摘要翻译： 公开了使用UDP-葡萄糖糖蛋白糖基转移酶1（UGGT1）或其编码基因的药物组合物，筛选方法等。 与已知的胰腺β细胞增殖因子相比，UGGT1具有极高的增殖活性; 因此，UGGT1可以在不作任何修饰的情况下用作糖尿病的有用治疗剂，并且还可用作开发新的糖尿病治疗剂的靶物质。

公开(公告)号：EP2582628A1

公开(公告)日：2013-04-24

申请号：EP11795287.9

申请日：2011-06-17

申请人： BASF SE ,  Tokyo Institute of Technology

发明人： YILMAZ, Bilge ,  MÜLLER, Ulrich ,  PFAFF, Meike ,  GIES, Hermann ,  XIAO, Feng-Shou ,  TATSUMI, Takashi ,  BAO, Xinhe ,  ZHANG, Weiping ,  DE VOS, Dirk ,  IMAI, Hiroyuki ,  XIE, Bin ,  ZHANG, Haiyan

IPC分类号： C01B39/48 ,  B01J20/18

CPC分类号： C01B39/46 ,  B01D53/9418 ,  B01D2251/2067 ,  B01D2253/108 ,  B01D2253/3425 ,  B01D2255/20738 ,  B01D2255/20761 ,  B01D2255/50 ,  B01D2255/9207 ,  B01D2257/402 ,  B01D2257/404 ,  B01D2257/406 ,  B01D2258/012 ,  B01J20/186 ,  B01J20/28011 ,  B01J20/2803 ,  B01J20/28042 ,  B01J20/28057 ,  B01J29/70 ,  B01J2229/186 ,  C01B37/02 ,  C01B39/48 ,  C01P2006/12 ,  C07C1/20 ,  C07C2529/70 ,  C07C2529/80 ,  C10G3/49 ,  C10G11/18 ,  C10G25/03 ,  C10G2300/405 ,  C10G2300/70 ,  Y02C20/10 ,  Y02P20/153 ,  Y02P20/52 ,  Y02P30/20

摘要： Zeolitic materials of the LEV-type structure and methods for their production are provided. The method for producing of the zeolitic material having an LEV-type structure comprising Y0
2 and optionally comprising X
2 O
3 comprises the steps of: (1) preparing a mixture comprising one or more sources for Y0
2 , one or more solvents, and optionally comprising seed crystals; and (2) crystallizing the mixture obtained in step (1), wherein Y is a tetravalent element, and X is a trivalent element, the mixture crystallized in step (2) contains 3 wt.-% or less of one or more metals M based on 100 wt-% of Y0
2 , even more preferably contains no metal M, wherein M stands for sodium or potassium.

公开(公告)号：EP2568286A1

公开(公告)日：2013-03-13

申请号：EP11777474.5

申请日：2011-05-06

申请人： Tokyo Institute of Technology ,  Yamaguchi University

发明人： YAMASHITA Katsuko ,  FUKUSHIMA Keiko ,  HINODA Yuji

IPC分类号： G01N33/53 ,  G01N33/574

CPC分类号： G01N33/6893 ,  G01N33/57415 ,  G01N2333/4725

摘要： The object of the present invention is to provide a clinical marker capable of distinguishing breast cancer from interstitial pneumonia; and a clinical marker for detecting malignancy or progress level of breast cancer, and for monitoring effects of the treatment of breast cancer. The object can be solved by a method for analyzing mucin 1 having Siaα2-8Siaα2-3Galβ-R, characterized by comprising the step of bringing a first probe specifically binding to a mucin 1 having Siaα2-8Siaα2-3Galβ-R into contact with a sample to be tested.

摘要翻译： 本发明的目的是提供一种能区分乳腺癌和间质性肺炎的临床标志物; 以及用于检测乳腺癌的恶性程度或进展水平的临床标志物以及用于监测乳腺癌治疗效果的临床标志物。 该目的可以通过分析具有Siaα2-8Siaα2-3Galβ-R的粘蛋白1的方法来解决，其特征在于包括以下步骤：使与Siaα2-8Siaα2-3Galβ-R的粘蛋白1特异性结合的第一探针与样品接触 进行测试。