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518 条记录 (耗时 0.021 秒)

    Pesticidal 1-arylimidazoles
    63.
    发明公开
    Pesticidal 1-arylimidazoles 失效
    哌啶1-芳基咪唑。

    公开(公告)号：EP0484165A1

    公开(公告)日：1992-05-06

    申请号：EP91310094.7

    申请日：1991-10-31

    申请人： RHONE-POULENC AGROCHIMIE

    发明人： Powell, Gail Scotton ,  Sinodis, David Neal ,  Timmons, Philip Reid ,  Wu, Tai-Teh ,  Chou, David Teh Wei ,  Newsome, Peter Wyatt ,  Hall Lee S.

    IPC分类号： C07D233/84 ,  A01N43/50 ,  C07D233/86 ,  C07D233/88

    CPC分类号： C07D233/84 ,  A01N43/50 ,  A01N47/02 ,  C07D233/86 ,  C07D233/88

    摘要： The invention describes novel 1-arylimidazoles of formula (I),

    wherein typically preferred substituents are:
    X is S(O) n R₁, in which R₁ is unsubstituted or halo-substituted alkyl and n is 0, 1 or 2;
    Y is hydrogen, halogen, alkyl, alkoxy, alkoxyalkylideneimino, alkylsulfenyl, alkylsulfinyl or alkylsulfonyl;
    Z is hydrogen or alkyl;
    R₂ is halogen or alkylsulfenyl;
    R₃ and R₅ are hydrogen;
    R₆ is halogen; and
    R₄ is hydrogen, halogen, haloalkyl or haloalkoxy.
    The invention further describes processes to make the compounds, compositions of the compounds, and methods of use of the compounds for the control of arthropods (especially mites, aphids or insects), nematodes, helminths, or protozoa.

    摘要翻译： 本发明描述了式（I）的新型1-芳基咪唑，其中通常优选的取代基是：X是S（O）n R 1，其中R 1是未取代的或卤素取代的烷基，n是0,1或2; Y是氢，卤素，烷基，烷氧基，烷氧基亚烷基亚氨基，烷基亚磺酰基，烷基亚磺酰基或烷基磺酰基; Z是氢或烷基; R2是卤素或烷基亚磺酰基; R3和R5是氢; R6是卤素; 且R 4为氢，卤素，卤代烷基或卤代烷氧基。 本发明还描述了使化合物，化合物的组合物和化合物用于控制节肢动物（特别是螨虫，蚜虫或昆虫），线虫，蠕虫或原生动物的方法。

    Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same
    67.
    发明公开
    Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same 失效
    咪唑ivate ivate ivate。。。。。。。。。。。。。。。。。。。。。

    公开(公告)号：EP0412529A1

    公开(公告)日：1991-02-13

    申请号：EP90115236.3

    申请日：1990-08-08

    申请人： NIPPON CHEMIPHAR CO., LTD.

    发明人： Okabe, Susumu, 287-5, Shingoryouguchi-cho ,  Masaki, Mitsuo ,  Yamakawa, Tomio ,  Matsukura, Hitoshi ,  Nomura, Yustaka

    IPC分类号： C07D233/84 ,  A61K31/415

    CPC分类号： C07D233/84

    摘要： Disclosed are novel imidazole derivatives having the formula:
    wherein R¹ is hydrogen or an alkyl group having 1-6 carbon atoms, R² is an alkyl group having 2-6 carbon atoms substi­tuted with an alkoxy group having 1-4 carbon atoms, each of R³, R⁴, R⁵ and R⁶ independently is hydrogen, a halogen, an alkyl group having 1-6 carbon atoms, an alkoxy group having 1-6 carbon atoms, a fluorine-substituted alkyl group having 1-6 carbon atoms, or a fluorine-substituted alkoxy group having 1-6 carbon atoms. The new imidazole derivatives are effective particularly as anti-ulcer agents.

    摘要翻译： 公开了具有下式的新型咪唑衍生物：其中R 1是氢或具有1-6个碳原子的烷基，其中R 2是具有2-6个碳原子的烷基， 1-4个碳原子，R 3，R 4，R 5和R 6各自独立地是氢，卤素，具有1-6个碳原子的烷基，具有1- 6个碳原子，具有1-6个碳原子的氟取代的烷基或具有1-6个碳原子的氟取代的烷氧基。 新的咪唑衍生物特别有效地用作抗溃疡剂。

    Dopamine-beta-hydroxylase inhibitors
    69.
    发明公开
    Dopamine-beta-hydroxylase inhibitors 失效
    多巴胺-β-羟基酶抑制剂

    公开(公告)号：EP0323146A3

    公开(公告)日：1991-01-30

    申请号：EP88312193.1

    申请日：1988-12-22

    申请人： SMITHKLINE BECKMAN CORPORATION

    发明人： Kruse, Lawrence Ivan ,  Ross, Stephen Torey ,  Ohlstein, Eliot Howard

    IPC分类号： C07D233/84 ,  A61K31/415

    CPC分类号： C07D233/84

    摘要： Compounds of formula (I)
    and pharmaceutically acceptable salts or hydrates thereof are described in which, X is H, F, Cl, Br, I, C₁₋₄alkyl, CN, NO₂, SO₂NH₂, COOH, OH, CHO, C₁₋₄alkoxy, CH₂OH, CH₂OC₁₋₄alkyl, CF₃, C₂F₅, C₃F₇, SO₂CH₃, SO₂CF₃, or CO₂C a H 2a+1 wherein a is 1 to 5, or any accessible combination thereof up to 5 substituents; n is 0 to 5; m is 1 to 5; R is H or C₁₋₄alkyl. These compounds are dopamine-β-hydroxylase inhibitors. Pharmaceutical compositions are described as are methods of use. Processes for the preparation of these compounds are described.

    摘要翻译： 其中X为H，F，Cl，Br，I，C 1-4烷基，CN，NO 2，SO 2 NH 2，COOH，OH，CHO，C 1的化合物及其药学上可接受的盐或水合物 1-4烷氧基，CH2OH，CH2OC1-4烷基，CF3，C2F5，C3F7，SO2CH3，SO2CF3或CO2CaH2a + 1，其中a为1至5，或其任何可接近的组合，最多为5个取代基; n为0〜5; m为1〜5; R是H或C 1-4烷基。 这些化合物是多巴胺-β-羟化酶抑制剂。 药物组合物被描述为使用的方法。 描述了这些化合物的制备方法。