Abstract:
A system and method is provided for improved fluorescence decay time measurement. A digital heterodyning technique is disclosed in which a photon detector is sampled at a rate slightly faster than a digitally pulsed excitation signal. A resulting cross correlation frequency is low enough to be read by inexpensive electronics such as by a field programmable gate array. Phase information in the signal provides correlation with corresponding photon detections.
Abstract:
A correlation interferometric spectroscopy devices are described that detect the spectral characteristics of a sample wherein device consists of an electromagnetic radiation source for exciting a sample with photons; and a detector adapted to detect an arrival time of a photon at the detector and further adapted to detect a delay between the arrival time of different photons. The device may further consist of an autocorrelator adapted to analyze the between the arrival of photons at the detector. The device may also be used together with other spectral detection and characterizing systems, such as Raman spectroscopy and attenuated total reflectance spectroscopy. Also provided herein are methods, systems, and kits incorporating the correlation interferometric spectroscopy device.
Abstract:
A spectroscopic analysis of a sample (1) comprises arranging the sample (1) in a resonator cavity (10) being capable for transmitting cavity mode frequencies with a cavity mode frequency spacing, coupling pulsed source light into the resonator cavity (10), the source light comprising source comb frequencies with a source frequency spacing, coupling pulsed transmitted light out of the resonator cavity (10), and spectrally resolved detecting the transmitted light with a detector device (40), wherein the cavity mode frequency spacing and the source frequency spacing are detuned relative to each other, so that the transmitted light comprises transmitted comb frequencies with a spacing larger than the source frequency spacing, and the detecting step includes collecting spectral distributions of the transmitted light in dependence on relative positions of the cavity mode frequencies and the source comb frequencies, wherein the cavity mode frequencies and the source comb frequencies are varied relative to each other, so that the transmitted comb frequencies are varied within a predetermined spectral range of interest, and the spectral distributions of the transmitted light are collected such that different transmitted comb frequencies are individually resolved. Furthermore, a spectroscopic device (100) being adapted for the spectroscopic analysis of a sample (1) is described.
Abstract:
The invention relates to a device for optical spectroscopy with means for generating an interference pattern and with a spatially resolving detector that can receive the generated interference pattern. According to the invention, the wave fronts of at least one component beam being involved in the interference pattern are influenced by spectrally dispersive or diffractive optical elements according to the wavelength.
Abstract:
A spectrometer (10) includes a two-dimensional array of modulatable microm-irrors (18), a detector (20), and an analyzer (22). The micro-mirrors are positioned for receiving individual radiation components forming a part of a radiation source. The micro-mirrors are modulated at different modulation rates in order to reflect individual radiation components at known and different modulation rates. The micro-mirrors combine a number of the reflected individual radiation components and reflect them to the detector. The detector receives the combined radiation components and creates an output signal. The analyzer is coupled to the detector to receive the output signal and to analyze at least some of the individual radiation components making up the combined reflection. By using a micro-mirror array that modulates the radiation components at different rates, all of the radiations components can be focused onto a single detector to maximize the signal-to-noise ratio of the detector.