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622 条记录 (耗时 0.013 秒)

    BENZOTRIAZOLE DERIVATIVES AND REAGENTS CONTAINING SAME FOR ANALYZING CARBOXYLIC ACIDS
    81.
    发明公开
    BENZOTRIAZOLE DERIVATIVES AND REAGENTS CONTAINING SAME FOR ANALYZING CARBOXYLIC ACIDS 失效
    苯并呋喃衍生物，德国，德国，德国，瑞士分析师。

    公开(公告)号：EP0418385A1

    公开(公告)日：1991-03-27

    申请号：EP89906425.7

    申请日：1989-05-25

    申请人： SHIONOGI & CO., LTD.

    发明人： NARITA, Shigeru ,  KITAGAWA, Takayasu

    IPC分类号： C07D249/20 ,  C07D491/056 ,  G01N33/50 ,  G01N33/58

    CPC分类号： C07D491/04 ,  C07D249/20 ,  Y02P20/55 ,  Y10S436/815

    摘要： The invention provides compounds represented by formula (I) and their salts, wherein R¹ represents C₁-C₅ alkylene, R² and R³, which may be the same or different, each represents hydrogen, C₁-C₅ alkyl, C₁-C₅ alkyloxy, amino, mono- or di(C₁-C₅ alkyl) amino (provided that R² and R³ do not represent hydrogen at the same time) or, when taken together, epresent C₁-C₅ alkylenedioxy, and R⁴ represents hydrogen or C₁-C₅ alkyl. Since the compounds react with a carboxylic acid in a short time at room temperature in the presence of a condensing agent to produce amides emitting strong fluorescence,thus being useful as reagents for determining carboxylic acids rapidly with high sensitivity.

    摘要翻译： 本发明提供由式（I）表示的化合物及其盐，其中R 1表示C 1 -C 5亚烷基，R 2和R 3可以相同或不同，各自表示氢，C 1 -C 5 烷基，C 1 -C 5烷氧基，氨基，单 - 或二 - （C 1 -C 5烷基）氨基（条件是R 2和R 3不同时表示氢），或者一起表示C1 -C 5亚烷基二氧基，R 4表示氢或C 1 -C 5烷基。 由于化合物在缩合剂存在下在室温下在短时间内与羧酸反应，以产生发出强烈荧光的酰胺，因此可用作以高灵敏度快速测定羧酸的试剂。

    System and method for broad spectrum drug detection
    82.
    发明公开
    System and method for broad spectrum drug detection 失效
    用于广谱光谱检测的系统和方法

    公开(公告)号：EP0353015A3

    公开(公告)日：1990-12-12

    申请号：EP89307526.7

    申请日：1989-07-25

    申请人： BIO-RAD LABORATORIES, INC.

    发明人： Binder, Steven R.

    IPC分类号： G01N33/48 ,  G01N30/02

    CPC分类号： G01N33/94 ,  G01N30/88 ,  G01N2030/8804 ,  G01N2030/8813 ,  G01N2030/8831 ,  Y10S436/815 ,  Y10S436/901 ,  Y10T436/255

    摘要： Biological fluid test samples are analyzed for a broad spectrum of drugs, including benzodiazepines, amphetamines, tricyclic antidepressants and opiates, in a single isocratic analysis using a chromatographic column system containing three analytical columns -- an anion exchange column, a reversed phase column and a cation exchange column. A pre-column is also included to purge the sample of salts, proteins, peptides and hydrophilic anions. Carrier liquids containing aceto­nitrile at various strengths are used for distribution of the various drugs among the columns, elution of the drugs from the columns, and column purging and condition­ing. The system readily lends itself to automation, automatic periodic sampling, and component identification and quantification.

    DETECTION OF SKATOLE FOR MEAT QUALITY
    86.
    发明公开
    DETECTION OF SKATOLE FOR MEAT QUALITY 失效
    Skatol用于确定肉类质量检测。

    公开(公告)号：EP0368942A1

    公开(公告)日：1990-05-23

    申请号：EP89901240.0

    申请日：1988-12-12

    申请人： IDETEK, INC.

    发明人： SINGH, Prithipal ,  SINHA, Ashoke

    IPC分类号： C07K16 ,  G01N33

    CPC分类号： C07K16/44 ,  G01N33/5308 ,  Y10S435/81 ,  Y10S435/963 ,  Y10S436/809 ,  Y10S436/81 ,  Y10S436/815 ,  Y10S436/822

    摘要： Un procédé permet de détecter l'odeur sexuelle du verrat dans un échantillon de viande de porc. On combine des anticorps anti-scatole dans un tampon de réaction avec un échantillon prélevé sur un porc, afin de former un mélange de réaction. Après incubation, on détermine la quantité de formation de complexes scatole-anticorps. Dans un mode de réalisation particulier, le procédé utilise des anticorps fixés à un substrat solide dans un dosage d'inhibition concurrente avec un analogue de scatole marqué par une enzyme. Des kits facilitant la mise en oeuvre du procédé sont prévus.

    SPECIFIC IMMUNOASSAY FOR HEPARIN.
    88.
    发明公开
    SPECIFIC IMMUNOASSAY FOR HEPARIN. 失效
    特异性免疫试验程序肝素。

    公开(公告)号：EP0267951A4

    公开(公告)日：1989-02-23

    申请号：EP87903802

    申请日：1987-05-21

    申请人： UNIV NEW YORK

    发明人： GITEL SANFORD ,  WESSLER STANFORD

    IPC分类号： G01N33/53 ,  C08G73/00 ,  C12Q1/00 ,  C12Q1/28 ,  C12Q1/42 ,  G01N33/86 ,  G01N33/94

    CPC分类号： G01N33/86 ,  G01N33/94 ,  G01N2400/40 ,  Y10S435/81 ,  Y10S436/808 ,  Y10S436/815

    摘要： Assay for measuring heparin in a biological fluid by incubating the fluid in the presence of an immobilized heparin inhibitor (preferably a positively charged polymer of 1-ethyl-3-(3-dimethylaminopropyl)carboiimide) causing the heparin to bind to the inhibitor forming a 2-component complex; incubating the two-component complex with an anti-heparin antibody causing the antibody to bind to the complex forming a three-component heparin/inhibitor/anti-heparin complex; incubating said three-component complex with detectable second antibody recognizing said anti-heparin antibody forming a four-component heparin/inhibitor/anti-heparin (second antibody) complex and detecting the amount of said second antibody in said four-component complex.

    Multizone analytical element having labeled reagent concentration zone
    89.
    发明公开
    Multizone analytical element having labeled reagent concentration zone 无效
    具有标签试剂浓度区的多分辨分析元件

    公开(公告)号：EP0212603A3

    公开(公告)日：1988-11-30

    申请号：EP86111379

    申请日：1986-08-18

    申请人： MILES INC.

    发明人： Greenquist, Alfred C.

    IPC分类号： G01N33/52 ,  G01N33/543

    CPC分类号： G01N33/54386 ,  G01N33/525 ,  Y10S435/805 ,  Y10S435/968 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/815

    摘要： A multizone test device for the determination of analyte from a liquid test medium upon contact with the liquid test medium and a labeled reagent comprising a chemical group having a detectable chemical property. The test device preferably comprises multilayers including a reagent layer incorporated with an immobilized reagent and a detection layer incorporated with an immobilized form of an interactive detection reagent for the labeled reagent. The immobilized reagent and the labeled reagent comprise specific binding partners which will bind to each other dependent upon the amount of analyte present. Labeled reagent which does not become bound to the immobilized reagent in the reagent layer migrates into the detection layer and becomes bound to and immobilized by the immobilized binding substance therein. As a result, reverse migration of the labeled reagent into the reagent layer is prevented and the detectable physical property provided by the label of the labeled reagent is localized in the detection layer for the precise measurement thereof and correlation to the amount of analyte in the test medium.