PROCESS FOR PREPARING CONTROL SAMPLES OF PARTICLES SUCH AS MICROORGANISMS AND CELLS
    84.
    发明公开
    PROCESS FOR PREPARING CONTROL SAMPLES OF PARTICLES SUCH AS MICROORGANISMS AND CELLS 有权
    方法颗粒制造如何微生物和细胞的对照样品

    公开(公告)号:EP1263983A1

    公开(公告)日:2002-12-11

    申请号:EP01911266.3

    申请日:2001-03-12

    申请人: BTF Pty Ltd.

    摘要: Processes for preparing controlled samples of particles, including microorganisms and cells are described. A sample of particles is provided and separated into a predetermined number of desired particles by particle separation means. The predetermined number of particles is dispensed into a receptacle or onto a surface in accordance with a sorting instruction, with the receptacle or surface being positioned by collecting means so as to receive the dispensed particles. A sorting instruction from the particle dispensing means activates the collecting means such that when a sorting instruction has been actuated, so as to deliver a predetermined number of particles into a receptacle or onto a surface which is positioned accurately for sufficient time to collect all sorted particles, the collecting means advances and positions a subsequent surface or receptacle for receipt of particles, the collector means thereafter signalling the particle separation means to commence the next sorting instruction.

    AUTOMATISCHE KONTROLLE UND STEUERUNG DES TENSIDGEHALTS IN WÄSSRIGEN PROZESSLÖSUNGEN
    85.
    发明授权
    AUTOMATISCHE KONTROLLE UND STEUERUNG DES TENSIDGEHALTS IN WÄSSRIGEN PROZESSLÖSUNGEN 有权
    自动控制和控制水性表面活性剂PROCESS SOLUTIONS

    公开(公告)号:EP1068525B1

    公开(公告)日:2002-07-31

    申请号:EP99915688.8

    申请日:1999-03-23

    IPC分类号: G01N33/18

    摘要: The invention relates to a method for automatically testing and controlling the surface-active contents in aqueous solutions used in a process. According to said method, the following operations are carried out under control of a program: a) a sample having a predetermined volume is extracted from the aqueous solution; b) solids contained in said sample are optionally removed; c) said sample is optionally diluted in water at a ratio which is predetermined or determined based on the result of a preliminary determination; d) the surface-active contents is determined by selective adsorption, by electrochemical or chromatographic approach, by dissociation into volatile components, by stripping of said volatile components and their detection, or by addition of a reactive agent which modifies the interaction of said sample with an electromagnetic radiation proportionally to the surface-active contents and by measuring the variation of said interaction; e) the result of said determination is stored on a data medium or used as a base for further computation and/or the result of said determination or of further determinations is transmitted to a remote place from where it is possible to take action in the course of the determinations. Measurements for monitoring the bath can be carried out automatically based on predetermined criteria or on demand from a remote place. The inventive method reduces the personnel required for controlling and monitoring the bath and increases process safety.

    PROTEIN LOCALIZATION ASSAYS FOR TOXICITY AND ANTIDOTES THERETO
    87.
    发明公开
    PROTEIN LOCALIZATION ASSAYS FOR TOXICITY AND ANTIDOTES THERETO 审中-公开
    蛋白分离法用于确定毒性和解药

    公开(公告)号:EP1185864A1

    公开(公告)日:2002-03-13

    申请号:EP00939864.5

    申请日:2000-06-14

    IPC分类号: G01N33/50

    CPC分类号: G01N33/5014 Y10T436/12

    摘要: Intracellular translocation of proteins, particularly protein kinase C (PKC) isoenzymes, provides a surrogate test system for determining toxicity of candidate compounds. The profile of translocation with respect to at least one and preferably two or more signal transduction proteins can be correlated with that of known toxins. In addition, databases of such profiles with respect to toxins of various types provide a useful set of standards for evaluating toxicity of candidate compounds. Moreover, to the extent that a toxin's profile mimics that found in a diseased state, the toxin can be used to construct screens for compounds alleviating the disease.

    THE USE OF INFRARED RADIATION IN DETECTION METHODS TO DEFOAM AQUEOUS SYSTEMS
    90.
    发明公开
    THE USE OF INFRARED RADIATION IN DETECTION METHODS TO DEFOAM AQUEOUS SYSTEMS 失效
    红外辐射源,用于在ENTSCHÄNMEN水系统中检测方法使用

    公开(公告)号:EP0946239A1

    公开(公告)日:1999-10-06

    申请号:EP97938421.0

    申请日:1997-08-20

    申请人: ECOLAB INC.

    IPC分类号: B01D19 C02F1 G05D23

    CPC分类号: B01D19/04 Y10T436/12

    摘要: We have found that foam generated from an aqueous medium can have a thermal insulating effect. The creation of a substantial volume of foam on the surface of an aqueous medium can reduce the apparent thermal IR emission substantially when compared to that of the aqueous medium free of foam. This difference in infrared emission can be used to control the addition of a defoaming agent to control foam in the aqueous medium. In the foam control method of the invention, an infrared detector is used to measure the infrared emission of an aqueous medium free of foam and during operations such a measurement is compared to the infrared emission of the aqueous medium under foaming conditions. As foam develops on the surface of the aqueous medium, the apparent thermal infrared emission from the foam is less than that of the aqueous medium free of foam. As the thermal IR emissions drop as foam develops, the difference between the apparent temperature of the foam and the aqueous medium, as measured as infrared thermal emissions, drops. Such a drop in temperature can be used to trigger the addition of a defoaming agent which can substantially reduce foam volume. As the foam volume is reduced, the thermal infrared emission of the aqueous medium returns to a value near the thermal inverting emission of the aqueous medium without foam. At this point, the addition of a defoaming composition is substantially reduced or stopped. During the control method, a predetermined limit is established at which the defoaming composition is introduced into the aqueous medium. As long as the thermal infrared emission of the foamed aqueous medium is different than the thermal infrared emission of the aqueous medium without foam, the defoaming agent is continually added to the aqueous medium. Further, the method permits the amount of defoaming agent added to the aqueous medium to be in proportion to the difference in infrared emission above the preset predetermined limit.