摘要:
A method for treating cancer by using an agent which is capable of inhibiting the functionality of the MCM complex, a heterohexameric ring formed from six subunits, in the process of DNA replication and a method of screening for such agents by detecting the locations and functions of the MCM subunits, such as hMcm2 and hMcm6, in cells treated with candidate compounds.
摘要:
A server-assisted computational method for computing the RSA cryptography is delineated in this document. The method enables public-key functions on the resource-constrained devices, such as a mobile phone or a PDA, by leveraging the rich computing resources provided by the server-grade computers on the network. Public-key processing, which is computationally intensive, as commonly known, if loaded solely on the constrained device, would easily overwhelm the processor capacity and electrical power supply. The server-assisted method enables such device to drive a powerful server computer on the Internet to carry out the public-key number-crunching job for its sake. Some near-completion results are communicated back to the device. From that, the final public-key cryptograph is derived. Privacy and security are the utmost important considerations in public-key systems. The present invention ensures the privacy of the device by blinding the server of the secret message and the crypto keys of the device. The merit is that the client device is able to accomplish the public-key processing with the help of the server, but without compromising the private crypto keys and confidential message code to the server.
摘要:
An organic compound, a donor-acceptor conjugated polymer, a formulation and a thin film, wherein a solution of the donor-acceptor conjugated polymer exhibits a peak optical absorption spectrum red shift of at least 100 nm when the donor-acceptor conjugated polymer solution is cooled from 140° C. to room temperature.
摘要:
A power controller for an AC power converter connected in series with a load and receiving power from or delivering power to a power source, the power controller comprising: a radial control block controlling a radial component of an electrical parameter of the AC power converter; and a chordal control block controlling a chordal component of the electrical parameter of the AC power converter. Also provided is a power system comprising one or more loads each connected in series to a power converter each controlled by a power controller as described above. There is also provided a method of controlling an AC power converter connected in series with a load and receiving power from a power source, the method comprising: controlling a radial component of an electrical parameter of the AC power converter; and controlling a chordal component of the electrical parameter of the AC power converter.
摘要:
On field ionization under ambient conditions is described and applied on both ionization and desorption of various chemicals and biochemical present on the surface of materials in solid, liquid or gas states. The Atmospheric Pressure Megavolt Electrostatic Field Ionization Desorption (APME-FID) method generates ions directly from the surface of samples connected to a high electrical voltage at megavolt conditions. Megavolt electrostatic potential is generated and gradually accumulated directly on the sample surface by a Van de Graaff generator without causing damage to the sample. Therefore, when coupled with mass spectrometric system, the APME-FID-MS method enables direct detection of analytes on the surface of samples in different sizes and diverse types.
摘要:
The present invention provides a wireless power transmitter comprising at least two loops, and separate drivers, each driving a respective one of the loops and providing a respective alternating current to the respective loop, thereby to transmit wireless power for receipt by at least one wireless power receiver. Also provided is a wireless power receiver comprising a receiver loop, and at least two focusing loops. An associated system and an associated method are also provided.
摘要:
Systems, methods, and devices are provided for controlling a movable object using multiple sensors. In one aspect, a method for determining initialization information for a movable object comprises: detecting, with aid of one or more processors, that the movable object has started operating; receiving, at the one or more processors, inertial data from at least one inertial sensor carried by the movable object; receiving, at the one or more processors, image data from at least two image sensors carried by the movable object; and determining, with aid of the one or more processors, the initialization information for the movable object based on the inertial data and the image data, wherein the initialization information one or more of a position of the movable object, a velocity of the movable object, or an orientation of the movable object relative to a gravity direction when the movable object started operating.
摘要:
This invention provides several ways of managing GC bias that occurs during seequencing and analysis of genomic DNA. Maternal plasma can be used as a source of fetal DNA for analysis. DNA segments or tags obtained from the plasma can be aligned with a chromosomal region of interest and with an artificial reference chromosome assembled from regions of the genome having matching GC content. This technology can be used, for example, to detect and evaluate aneuploidy and other chromosomal abnormalities.
摘要:
Progress of chromosomal aberrations in an organism is determined using biological samples including nucleic acid molecules originating from normal cells and potentially from cells associated with a disease, at least some of the nucleic acid molecules being cell-free. Non-overlapping chromosomal regions of a reference genome of the organism are determined. At a plurality of times: for each of plural nucleic acid molecules, a location thereof in the reference genome is determined; and for each chromosomal region: a respective group of nucleic acid molecules is identified as being therefrom based on the identified locations; a respective value defining a property of the nucleic acid molecules is calculated and compared to a reference value to determine a classification of whether the chromosomal region exhibits a deletion or an amplification. The classifications at the plurality of times are used to determine the progress of the chromosomal aberrations in the organism.