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公开(公告)号：EP1545466A1
公开(公告)日：2005-06-29
申请号：EP03799403.5
申请日：2003-10-02
CPC分类号： A61C8/0012 , A61B17/72 , A61B17/80 , A61B17/866 , A61F2/28 , A61F2/2875 , A61F2/32 , A61F2002/30535 , A61F2250/0058 , A61L27/12 , C04B28/34 , C04B32/00 , C04B38/0025 , C04B38/009 , C04B2111/00793 , C04B2111/0081 , C04B2111/00836 , Y10S977/906 , C04B22/085 , C04B22/16 , C04B38/0051 , C04B38/0074 , C04B38/0615 , C04B38/08 , C04B40/0028 , C04B40/0263 , C04B41/46 , C04B2103/0067 , C04B22/064 , C04B35/447
摘要： Shaped, preferably porous, inorganic bodies are provided which are prepared from a reactive blend. In accordance with one preferred embodiment, the solution is absorbed into a porous sacrificial substrate such as a cellulose sponge. The solution-saturated substrate is heated and an oxidation-reduction reaction occurs thereby forming an inorganic solid. A shaped, inorganic body is formed in situ. Optional, but preferred additional thermal treatment of the shaped, inorganic body removes the organic substrate, leaving an inorganic body that faithfully mimics the porosity, shape, and other physical characteristics of the organic substrate. Inorganic substrates may also be used to good effect. Large varieties of shaped bodies can be prepared in accordance with other embodiments of the invention and such shapes find wide use in surgery, laboratory and industrial processes and otherwise. The invention also provides chemically and morphologically uniform powders, including those having uniformly small sizes.
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公开(公告)号：EP1463465A1
公开(公告)日：2004-10-06
申请号：EP02805552.3
申请日：2002-12-09
发明人： BAGGA, Charanpreet, S. , ERBE, Erik, M. , MURPHY, James, P. , FREID, James, M. , POMRINK, Gregory, J.
IPC分类号： A61F2/44
CPC分类号： A61F2/442 , A61B17/1659 , A61B17/1671 , A61B17/86 , A61F2/30965 , A61F2/36 , A61F2/44 , A61F2/4455 , A61F2/447 , A61F2/4611 , A61F2/4684 , A61F2002/2835 , A61F2002/2892 , A61F2002/30062 , A61F2002/3008 , A61F2002/30133 , A61F2002/30448 , A61F2002/305 , A61F2002/30578 , A61F2002/30599 , A61F2002/30616 , A61F2002/30617 , A61F2002/30784 , A61F2002/30828 , A61F2002/30904 , A61F2002/30957 , A61F2002/3631 , A61F2002/4475 , A61F2002/4622 , A61F2002/4623 , A61F2002/4627 , A61F2002/4628 , A61F2002/4629 , A61F2002/4681 , A61F2210/0004 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2230/0015 , A61F2250/0063 , A61F2250/0097 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00161 , A61F2310/00179 , A61F2310/00293 , A61F2310/00329 , A61L27/446 , A61L27/50 , A61L31/16 , A61L31/18 , A61L2430/38 , C08L33/06
摘要： A spinal implant comprising an anterior side (60), posterior side (70), a pair of side walls (40) which are generally outwardly curved; top (20) and bottom (30) surfaces each including a plurality of projections (25) ; and a handling feature comprising at least one of a pair of side recesses (43, 53) for receiving a manipulator and a front recess (63), the handling feature facilitating handling and insertion of the spinal implant into an intervertebral space.
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公开(公告)号：EP2474286A1
公开(公告)日：2012-07-11
申请号：EP12151422.8
申请日：2005-02-03
发明人： Erbe, Erik M. , Clineff, Theodore D. , Bagga, Charanpreet S. , Nagvajara, Gina M. , Koblish, Antony , Brown, Steven B.
IPC分类号： A61F2/00 , A61F2/30 , A61F2/34 , A61F2/36 , A61F2/78 , A61L27/46 , A61L27/54 , A61L27/56 , A61L27/58
CPC分类号： A61F2/28 , A61B17/80 , A61B17/8095 , A61B17/86 , A61B2017/00004 , A61F2/2803 , A61F2/2875 , A61F2/30767 , A61F2/3094 , A61F2/30965 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/389 , A61F2/4241 , A61F2/4644 , A61F2002/2817 , A61F2002/2825 , A61F2002/2835 , A61F2002/2882 , A61F2002/30004 , A61F2002/30011 , A61F2002/30014 , A61F2002/30062 , A61F2002/3008 , A61F2002/30092 , A61F2002/30118 , A61F2002/30153 , A61F2002/30224 , A61F2002/30225 , A61F2002/30235 , A61F2002/30237 , A61F2002/30238 , A61F2002/30247 , A61F2002/30265 , A61F2002/30281 , A61F2002/30291 , A61F2002/30324 , A61F2002/30622 , A61F2002/30677 , A61F2002/30678 , A61F2002/30736 , A61F2002/30785 , A61F2002/30828 , A61F2002/30838 , A61F2002/30909 , A61F2002/30925 , A61F2002/4631 , A61F2210/0004 , A61F2210/0014 , A61F2230/0006 , A61F2230/0019 , A61F2230/0069 , A61F2230/0071 , A61F2230/0082 , A61F2230/0086 , A61F2230/0091 , A61F2250/0014 , A61F2250/0018 , A61F2250/0023 , A61F2250/0036 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023 , A61F2310/00293 , A61F2310/00365 , A61F2310/00383 , A61F2310/00407 , A61L27/46 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/412 , A61L2300/64 , A61L2430/02 , Y10S514/801
摘要： Biocompatible bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities are described herein ( Figure 2 ). A pliable bone restorative having an osteoconductive foam that at least partially surrounds a biocompatible mesh and the foam comprises a biocompatible, resorbable polymer and calcium phosphate is also described.
摘要翻译： 本文描述了具有生物相容性，可再吸收聚合物和显示宏观，中观和微孔的生物相容性可再吸收的无机材料的生物相容性骨移植材料（图2）。 具有骨传导性泡沫的柔韧性骨修复体，其至少部分地围绕生物相容的网，并且泡沫包括生物相容性，可再吸收的聚合物和磷酸钙。
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公开(公告)号：EP2068758A2
公开(公告)日：2009-06-17
申请号：EP07861377.5
申请日：2007-09-25
CPC分类号： A61L27/446 , A61L27/44 , A61L27/54 , A61L2300/102 , A61L2430/02 , A61L2430/38 , C08L71/02
摘要： Methods of preparing bioactive composites are described. Also described are methods of molding such composites. Shaped bodies comprising bioactive composites are further described.
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公开(公告)号：EP1663041B1
公开(公告)日：2009-12-30
申请号：EP04782989.0
申请日：2004-09-02
发明人： BAGGA, Charanpreet, S. , GILBERT, Stephen, G. , KOBLISH, Antony , PERSENAIRE, Maarten , ERBE, Erik, M.
CPC分类号： A61B17/1604 , A61B17/16 , A61B17/1617 , A61B17/1671 , A61B17/8811 , A61B17/8819 , A61B17/8822 , A61B17/8858 , A61B2017/00867 , A61B2017/1602 , A61F2/4601
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公开(公告)号：EP1727489A2
公开(公告)日：2006-12-06
申请号：EP05712625.2
申请日：2005-02-03
发明人： ERBE, Erik, M. , CLINEFF, Theodore, D. , BAGGA, Charanpreet, S. , NAGVAJARA, Gina, M. , KOBLISH, Antony , BROWN, Steven, B.
CPC分类号： A61F2/28 , A61B17/80 , A61B17/8095 , A61B17/86 , A61B2017/00004 , A61F2/2803 , A61F2/2875 , A61F2/30767 , A61F2/3094 , A61F2/30965 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/389 , A61F2/4241 , A61F2/4644 , A61F2002/2817 , A61F2002/2825 , A61F2002/2835 , A61F2002/2882 , A61F2002/30004 , A61F2002/30011 , A61F2002/30014 , A61F2002/30062 , A61F2002/3008 , A61F2002/30092 , A61F2002/30118 , A61F2002/30153 , A61F2002/30224 , A61F2002/30225 , A61F2002/30235 , A61F2002/30237 , A61F2002/30238 , A61F2002/30247 , A61F2002/30265 , A61F2002/30281 , A61F2002/30291 , A61F2002/30324 , A61F2002/30622 , A61F2002/30677 , A61F2002/30678 , A61F2002/30736 , A61F2002/30785 , A61F2002/30828 , A61F2002/30838 , A61F2002/30909 , A61F2002/30925 , A61F2002/4631 , A61F2210/0004 , A61F2210/0014 , A61F2230/0006 , A61F2230/0019 , A61F2230/0069 , A61F2230/0071 , A61F2230/0082 , A61F2230/0086 , A61F2230/0091 , A61F2250/0014 , A61F2250/0018 , A61F2250/0023 , A61F2250/0036 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023 , A61F2310/00293 , A61F2310/00365 , A61F2310/00383 , A61F2310/00407 , A61L27/46 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/412 , A61L2300/64 , A61L2430/02 , Y10S514/801
摘要： Biocompatible bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities are described herein (Figure 2). A pliable bone restorative having an osteoconductive foam that at least partially surrounds a biocompatible mesh and the foam comprises a biocompatible, resorbable polymer and calcium phosphate is also described.
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公开(公告)号：EP0874601B1
公开(公告)日：2007-03-21
申请号：EP96944757.2
申请日：1996-12-06
发明人： ERBE, Erik, M.
CPC分类号： A61B17/8802 , A61B17/866 , A61F2/32 , A61F2/4455 , A61F2002/30772 , A61F2002/3208 , A61F2002/4631 , A61L27/025 , A61L27/446 , A61L27/46 , C03C10/0009 , C08K3/34 , C08L75/04 , C08L33/06 , C08L33/04
摘要： Novel fillers comprising combeite glass-ceramic are provided. Hardenable restorative compositions comprising particulate combeite glass-ceramic provide improved biocompatibility in bone restorations. Hard, shaped bodies for orthopaedic, dental and other uses are also provided.
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公开(公告)号：EP1663041A2
公开(公告)日：2006-06-07
申请号：EP04782989.0
申请日：2004-09-02
发明人： BAGGA, Charanpreet, S. , GILBERT, Stephen, G. , KOBLISH, Antony , PERSENAIRE, Maarten , ERBE, Erik, M.
CPC分类号： A61B17/1604 , A61B17/16 , A61B17/1617 , A61B17/1671 , A61B17/8811 , A61B17/8819 , A61B17/8822 , A61B17/8858 , A61B2017/00867 , A61B2017/1602 , A61F2/4601
摘要： Novel kits are provided for the delivery of restorative or injectable compositions into an intraosseous space or surgical defect comprising cannulae for accessing an intraosseous space, mandarins insertable into the cannulae and movable therein, one or more catheters and a system for the delivery of aliquots of restorative compositions into the space via catheters. Independant claims relate to the catheter having a high porosity tip (10) and to a microreamer having an expandable section comprising leaves that flex (13).
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9.发明公开STERILE POLYMERIZABLE SYSTEMS AND KITS AND METHODS OF THEIR MANUFACTURE AND USE 审中-公开无菌聚合系统和他们的生产和使用装置和方法
公开(公告)号：EP1359944A2
公开(公告)日：2003-11-12
申请号：EP01273524.7
申请日：2001-11-27
IPC分类号： A61L2/00
CPC分类号： A61L2/081 , A61L2/0017 , A61L2/0023 , A61L2/022 , A61L2/04 , A61L2/206 , A61L2202/24
摘要： The present invention overcomes the difficulties in the sterilization and delivery of viscous, multi-component compositions that require pre-mixing prior to usage by disclosing a sterile, multi-component, ready-to-use product wherein each component is sterilized independently and then assembled into a sterilized delivery kit. In certain preferred embodiments of the present invention, a sterile, polimerizable system is provided that comprises a plurality of sterile polymerizable monomers, said monomers having been sterilized by passing them through a filter; at least one sterile filler which has been exposed to conditions effective to render said filler sterile, and the sterile monomers and the sterile filler being blended together to form at least one substantially homogeneous blend contained within a sterile delivery vessel. Still other embodiments include a single-use kit that comprises a delivery gun, mix tips, and cartridges that comprise one or more pastes of the present invention that are housed within one or more pouches to ensure sterility of the internal contents.
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