公开(公告)号：EP4226407A1

公开(公告)日：2023-08-16

申请号：EP21794702.7

申请日：2021-10-11

申请人： Dublin City University

发明人： MCNALLY, Patrick ,  COATES, David ,  MACGEARAILT, Niall ,  KELLY, Seán ,  VIJAYARAGHAVAN, Rajani K.

IPC分类号： H01J37/32

公开(公告)号：EP4038492A1

公开(公告)日：2022-08-10

申请号：EP20775802.0

申请日：2020-09-30

申请人： Dublin City University

发明人： CLARKE, Paul ,  MCCARREN, Andrew

IPC分类号： G06F8/72

公开(公告)号：EP3821252A1

公开(公告)日：2021-05-19

申请号：EP19746438.1

申请日：2019-07-09

申请人： Dublin City University

发明人： COLLINS, Denis ,  GAYNOR, Nicola ,  CROWN, John ,  O'DONOVAN, Norma

IPC分类号： G01N33/574

公开(公告)号：EP2593229B1

公开(公告)日：2020-05-13

申请号：EP11736040.4

申请日：2011-07-13

申请人： Dublin City University

发明人： LEONARD, Paul ,  DIMOV, Ivan ,  O'KENNEDY, Richard ,  FITZGERALD, Valerie

IPC分类号： B01L3/00

公开(公告)号：EP2756565B1

公开(公告)日：2018-10-31

申请号：EP12769995.7

申请日：2012-09-12

申请人： Dublin City University

发明人： ANANDARAJAH, Prince ,  LATKOWSKI, Slywester ,  BARRY, Liam

IPC分类号： H01S5/40 ,  H01S5/065 ,  H01S5/042

CPC分类号： H01S5/065 ,  H01S5/0064 ,  H01S5/0085 ,  H01S5/0427 ,  H01S5/0656 ,  H01S5/1096 ,  H01S5/40 ,  H01S5/4006 ,  H04B10/506

摘要： The present application provides an optical comb source in which the comb is produced by seeding a gain switched Fabry-Pérot laser with light from a single mode laser, while at the same time driving the Fabry-Pérot laser with a DC bias and RF signal.

公开(公告)号：EP2994232A1

公开(公告)日：2016-03-16

申请号：EP14730523.9

申请日：2014-06-13

申请人： Dublin City University

发明人： KINAHAN, David ,  DUCREE, Jens ,  DIMOV, Nikolay ,  KEARNEY, Sinead ,  VERESHCHAGINA, Elizaveta ,  GAUGHRAN, Jennifer ,  BURGER, Robert ,  BARRETT, Louise

IPC分类号： B01L3/00 ,  F16K99/00

CPC分类号： B01L3/502738 ,  B01L3/50273 ,  B01L2200/0605 ,  B01L2200/0621 ,  B01L2200/0684 ,  B01L2300/049 ,  B01L2300/0803 ,  B01L2300/0861 ,  B01L2300/0874 ,  B01L2300/0883 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/046 ,  B01L2400/0487 ,  B01L2400/0638 ,  B01L2400/0677 ,  F16K99/0017 ,  F16K99/003 ,  F16K99/0063 ,  F16K2099/0084

摘要： Microfluidic devices and in particular microfluidic devices incorporating a cascading valve arrangement for selectively controlling the flow of a fluid within the microfluidic device are described. Specific examples of a microfluidic device comprising a sacrificial valve (210) whose opening is triggered by the opening of a second valve (220), causing a retraction of a fluid spacer (213) thus bringing liquid (214) into contact with the dissolvable valve membrane (210).

摘要翻译： 描述了微流体装置，特别是包含级联阀装置的微流体装置，用于选择性地控制微流体装置内流体的流动。 包括牺牲阀（210）的微流体装置的具体实例，所述牺牲阀（210）的开口由第二阀（220）的打开触发，引起流体垫片（213）的缩回，从而使液体（214）与可溶解阀 膜（210）。

公开(公告)号：EP2906945A1

公开(公告)日：2015-08-19

申请号：EP13779768.4

申请日：2013-10-09

申请人： Dublin City University

发明人： KILLARD, Anthony ,  HIBBARD, Troy ,  CROWLEY, Karl

IPC分类号： G01N33/497

CPC分类号： G01N33/497 ,  A61B5/082 ,  A61B5/097 ,  G01N27/021 ,  G01N2033/4975 ,  Y10T436/175383 ,  Y10T436/255 ,  Y10T436/25875

摘要： A system for sensing and measuring ammonia in a breath sample is described. The system includes a sampling means for capturing and directing a breath sample from a subject to an ammonia sensor, the ammonia sensor including a conducting polymer polyaniline sensor. The sampling means includes a breath sample capture chamber, the chamber having an inlet and outlet, the inlet having a first valve through which a breath is exhaled into the sample capture chamber, the outlet having a second valve through which breath surplus to the volume of the chamber is expelled, to provide capture of a breath sample of predefined volume.

公开(公告)号：EP2905619A1

公开(公告)日：2015-08-12

申请号：EP14154030.2

申请日：2014-02-05

申请人： Dublin City University

发明人： Clynes, Martin ,  Dowling, Paul ,  Clarke, Colin

IPC分类号： G01N33/574

CPC分类号： G01N33/57415 ,  G01N33/57488

摘要： A method of monitoring a breast cancer patient's response to treatment, or of detecting recurrence of breast cancer, the method comprising a step of assaying a plurality of samples obtained from the patient over a period of time for expression levels of a plurality of biomarkers including Cancer Antigen 15-3 (CA 15-3) and one of either Glutamate or 12-Hydroxyeicosatetraenoic acid (12-HETE), and detecting a change in expression levels of CA 15-3 and one (or both) of either Glutamate or 12-HETE over the time period, wherein detection of a decreased expression levels of CA 15-3 and one of either Glutamate or 12-HETE over the time period is indicative of a response to therapy and wherein detection of increased or stable expression levels of CA 15-3 and one of either Glutamate or 12-HETE over the time period is indicative of a non-response to breast cancer therapy.

摘要翻译： 监测乳腺癌患者的治疗，或检测乳腺癌复发的应答的方法，该方法包括：在对生物标记物，包括癌症的多个表达水平在一段时间内测定从患者获得的样品中的多个步骤 抗原15-3（CA 15-3），要么谷氨酸或12-羟二十酸（12-HETE）中的一个，和检测在谷氨酸单个或CA 15-3和一个（或两个）的表达水平的变化-12- HETE在TIMEPERIOD，CA 15-3的降低的表达水平的worin检测和一个无论是谷氨酸或12-HETE在TIMEPERIOD的指示对治疗和CA 15的worin增加的或稳定的表达水平的检测的响应的 -3和要么谷氨酸或12-HETE在TIMEPERIOD之一是指示非响应于乳腺癌的治疗。

公开(公告)号：EP2569613B1

公开(公告)日：2014-11-12

申请号：EP11723338.7

申请日：2011-05-11

申请人： Dublin City University ,  Åmic AB

发明人： BAKKER, Jim Writser Peter ,  OHMAN, Ove ,  KURZBUCH, Dirk ,  RUCKSTUHL, Thomas ,  MACCRAITH, Brian ,  O'DRISCOLL, Stephen

IPC分类号： G01N21/64

CPC分类号： G01N21/64 ,  G01N21/645 ,  G01N21/6452 ,  G01N21/648 ,  G01N21/66 ,  G01N21/76 ,  G01N33/54373

公开(公告)号：EP2154704B9

公开(公告)日：2014-01-15

申请号：EP09175177.6

申请日：2006-05-11

申请人： Dublin City University

发明人： Ellingboe, Albert R.

IPC分类号： H01J37/32

CPC分类号： H01J37/32165 ,  H01J37/32082 ,  H01J37/32174 ,  H01J37/32568