Abstract:
The invention relates to a combined two-compartment device for diagnosing body liquids, which comprises: (a) an upper compartment for collecting and storing the body liquid; (b) a lower diagnostic compartment for diagnosing the body liquid at a diagnostic stage, said diagnostic compartment comprises a diagnostic strip; (c) an opening at the bottom wall between said upper compartment and said lower compartment, wherein said opening is kept blocked by a suitable valve until just before said diagnostic stage; and (d) a mechanism for releasing said blockage of said opening, thereby to allow flow of the body liquid to said lower compartment, and thereby to come into contact with said diagnostic strip and to affect the diagnostic strip accordingly.
Abstract:
A kit for centrifugal isolation of a fraction of interest from a multi component-composition according to density, comprising: a separation chamber (100, 200) having an inlet (110, 210) for introducing the multi-component composition and a base through-hole (120, 220); characterized in that the separation chamber (100, 200) comprises: an inlet section (111, 211) communicating with the inlet (110, 210); a base section (112, 212) communicating with the base through-hole (120, 220); wherein the inlet section (111, 211) and the base section (112, 212) communicate with each other via a necked duct (130, 230) for detaching the inlet section (111, 211) and the base section (112, 212) at the necked duct (130, 230).
Abstract:
Microfluidic devices and in particular microfluidic devices incorporating a cascading valve arrangement for selectively controlling the flow of a fluid within the microfluidic device are described. Specific examples of a microfluidic device comprising a sacrificial valve (210) whose opening is triggered by the opening of a second valve (220), causing a retraction of a fluid spacer (213) thus bringing liquid (214) into contact with the dissolvable valve membrane (210).
Abstract:
The present invention relates to a contact-less priming system for loading a solution in a microfluidic device comprising: at least one microfluidic device, a pressure chamber configured to enclose said at least one microfluidic device, a pressurization unit fluidly connected to the pressure chamber and at least one closing member. The present invention also relates to a contact-less priming method for loading a solution in a microfluidic device.
Abstract:
A closure having enhanced oxygen barrier capabilities includes a cap body formed from a first material, the cap body defining a cavity therethrough, a stopper formed from a second material, the second material being different than the first material and disposed within the cavity, and a barrier layer formed from a third material, the third material being different than at least the second material and associated with at least one of the cap body and the stopper. A container assembly including a closure and a method of forming the closure is also provided.
Abstract:
An apparatus for concentrating cells in a suspension is described. The apparatus comprises: a sedimentation assembly (10, 48, 84) comprising a first chamber (12, 72, 86) for receiving a suspension including a cell population, and a second chamber (26, 76, 88) in fluid communication with said first chamber; and a centrifuge holder (44) for receipt within a centrifuge. The centrifuge holder has an interior chamber that is configured to cooperatively receive the sedimentation assembly to stabilize the assembly during centrifugation.
Abstract:
A nucleic acid amplification and detection kit, including: a buffer storage assembly, including a buffer storage reservoir storing a buffer solution therein; a nucleic acid amplification assembly including a nucleic acid amplification reservoir storing one or more reagents therein and configured to receive a sample containing nucleic acid for amplification therein, wherein the buffer storage assembly is configured to couple with the nucleic acid amplification assembly to seal within the nucleic acid amplification reservoir the sample containing nucleic acid and amplification products of the amplification; and a test strip assembly including a lateral flow test strip disposed therein, the test strip assembly and the coupled nucleic acid amplification and buffer storage assemblies being configured to couple with one another and including one or more solution release components to release the amplification products from the nucleic acid amplification reservoir onto the lateral flow test strip for testing, and to release the stored buffer solution from the buffer storage reservoir to flush the released amplification products along the lateral flow test strip.
Abstract:
The present invention relates to a fluid control and processing system (1) comprising a cartridge (2) and an instrument for operating the cartridge (2). The cartridge (2) comprises a cylinder body comprising a cylinder and a fluid port. It further comprises dispensing ports to drive at least a fluid flow, each dispensing port being positioned to be connectable, when the instrument is operating the cartridge (2), with at least a fluid port by rotation of the cylinder body. The instrument comprises a piston driver (8) for driving the piston (11). The fluid control and processing system further comprises: - reversible fastening means for fastening the piston (11) to the piston driver (8), so that the movement of the piston (11) is controlled by the piston driver (8); - rotating means for rotating the cylinder body.