摘要:
One-pack type perfusion liquid preparations which are excellent in the effect of protecting eye tissues and corneal endothelial cells during and after cataract operation, intraocular lens transplantation, glaucoma operation, vitreous body operation and penetrating keratoplasty, and have a high biological safety. These preparations comprise an aqueous solution containing at least one compound selected from among D-3-hydroxybutyric acid and salts thereof, a hydrogencarbonate and calcium glycerophosphate and remain stable as a preparation even under severe temperature conditions.
摘要:
A one-pack perfusate preparation for ophthalmic operation of cataract, glaucoma or intraocular lens transplantation, which is excellent in the protection of ophthalmic tissues and endothelial cells during and after the operation and has a high in vivo stability. The preparation comprises an aqueous solution of at least one compound selected among D-3-hydroxybutyric acid and water-soluble salts thereof, at least one compound selected among water-soluble bicarbonates, phosphoric acid and water-soluble phosphates, a water-soluble calcium salt, and a water-soluble magnesium salt.
摘要:
A one-pack irrigating solution preparation for ocular surgery of cataract, intraocular lens implantation, glaucoma, vitrectomy or penetrating keratoplasty, which is excellent in the protection of ocular tissues and corneal endothelial cells during and after the surgery and has a high in a living body safety. This preparation comprises an aqueous solution containing at least one compound selected from the group consisting of D-3-hydroxybutyric acid and its salts, bicarbonates, and calcium glycerophosphate and is stable under severe temperature conditions.
摘要:
An object of the present invention is to provide a nucleated tablet for contact lens (CL) cleaning that makes it possible to disinfect a CL simply and easily in the presence of a foaming component; a CL cleaning preparation that contains the nucleated tablet; and a method for cleaning a CL. The nucleated tablet for CL cleaning of the invention is a nucleated tablet including an outer shell that contains iodine-based bactericide, a carbonate, an organic acid, and a surfactant having, per partial weight of 2000 out of the molecular weight thereof, less than one hydroxyl group, and an inner nucleus that contains a neutralizing agent, a carbonate, an organic acid, and a surfactant, wherein the inner nucleus is coated for extended release.
摘要:
There are provided an ophthalmic composition that comprises 3-hydroxybutyric acid and/or salts thereof as active ingredients and is used to prevent desiccation of eyes and an ophthalmic composition that is used to treat tear dysfunction. By use of the ophthalmic compositions of the present invention, desiccation of the eyes can be inhibited and tear dysfunction can be treated. Therefore, by use of the compositions, discomforts caused by tear dysfunction, such as desiccation of the eyes, foreign-body sensation, feeling of discomfort on the eyes and eye strain, can be improved. Further, the ophthalmic compositions of the present invention can inhibit diseases caused by tear dysfunction, exemplified by development of dry eye and suspected dry eye which are dysfunctions related to desiccation of the eyes, particularly, development of diseases caused by tear dysfunction without injuries on the keratoconjunctive.
摘要:
A contact lens solution containing polylysine, polyphosphoric acid and/or its salt preventing polylysine from adsorption by contact lenses, a nitrogen-containing organic antibacterial agent other than polylysine and water. Contact lenses can be washed, disinfected and preserved merely by soaking in the above solution without rubbing or rinsing before putting into eyes.
摘要:
A preparation for simultaneously conducting disinfection, neutralization and cleaning of soft contact lenses, and a method for using easily, efficiently, and safely the preparation. The preparation comprises a combination of a first preparation containing an iodine disinfectant and a protease with a second preparation containing a reducing agent and a foaming agent and having a coating for delayed release, and a nonionic surfactant is contained in at least one of the first and second preparations. Soiled soft contact lenses are kept in an aqueous solution yellowed or browned with iodine molecules, and, after the aqueous solution has become substantially colorless, the lenses are separated from the aqueous solution, thus facilitating a series of procedures, that is, disinfection, neutralization, and cleaning.
摘要:
The present invention relates to a liquid preparation for soft contact lenses, particularly hydrogel contact lenses or silicone hydrogel contact lenses. The liquid preparation for contact lenses according to the present invention contains a hydrolyzed hyaluronic acid derivative having a monoether of a linear or branched alkyl group or alkenyl group having 6 or more and 20 or less carbon atoms and glycerol in a side chain. The liquid preparation for soft contact lenses according to the present invention may contain at least one cationic bactericide selected from the group consisting of an alexidine salt, a chlorhexidine salt, a polyhexamethylene biguanide salt and a quaternary ammonium salt. The liquid preparation for soft contact lenses according to the present invention is capable of suppressing adsorption of a cationic bactericide to soft contact lenses, and suppressing occurrence of corneal staining in a wearer