PERFUSION LIQUID PREPARATIONS FOR OPHTHALMIC OPERATIONS
    2.
    发明授权
    PERFUSION LIQUID PREPARATIONS FOR OPHTHALMIC OPERATIONS 有权
    灌注液体制剂用于眼科手术

    公开(公告)号:EP1247526B1

    公开(公告)日:2005-12-14

    申请号:EP00900174.4

    申请日:2000-01-11

    IPC分类号: A61K33/10 A61K9/08 A61P27/02

    摘要: One-pack type perfusion liquid preparations which are excellent in the effect of protecting eye tissues and corneal endothelial cells during and after cataract operation, intraocular lens transplantation, glaucoma operation, vitreous body operation and penetrating keratoplasty, and have a high biological safety. These preparations comprise an aqueous solution containing at least one compound selected from among D-3-hydroxybutyric acid and salts thereof, a hydrogencarbonate and calcium glycerophosphate and remain stable as a preparation even under severe temperature conditions.

    摘要翻译: 在白内障手术,人工晶状体移植,青光眼手术,玻璃体手术和穿透性角膜移植术期间和之后保护眼组织和角膜内皮细胞的效果优异并且具有高生物学安全性的单液型灌注液制剂。 这些制剂包含含有至少一种选自D-3-羟基丁酸及其盐,碳酸氢盐和甘油磷酸钙的化合物的水溶液,并且即使在苛刻的温度条件下也能保持稳定。

    OPHTHALMIC COMPOSITION FOR TREATING LACRIMAL DISORDERS
    7.
    发明公开
    OPHTHALMIC COMPOSITION FOR TREATING LACRIMAL DISORDERS 有权
    OPHTHALMISCHE ZUSAMMENSETZUNG ZUR BEHANDLUNG VON LAKRIMAL-ERKRANKUNGEN

    公开(公告)号:EP1674091A1

    公开(公告)日:2006-06-28

    申请号:EP04788468.9

    申请日:2004-09-30

    CPC分类号: A61K31/19 A61K9/0048

    摘要: There are provided an ophthalmic composition that comprises 3-hydroxybutyric acid and/or salts thereof as active ingredients and is used to prevent desiccation of eyes and an ophthalmic composition that is used to treat tear dysfunction. By use of the ophthalmic compositions of the present invention, desiccation of the eyes can be inhibited and tear dysfunction can be treated. Therefore, by use of the compositions, discomforts caused by tear dysfunction, such as desiccation of the eyes, foreign-body sensation, feeling of discomfort on the eyes and eye strain, can be improved. Further, the ophthalmic compositions of the present invention can inhibit diseases caused by tear dysfunction, exemplified by development of dry eye and suspected dry eye which are dysfunctions related to desiccation of the eyes, particularly, development of diseases caused by tear dysfunction without injuries on the keratoconjunctive.

    摘要翻译: 提供了一种眼科组合物,其包含3-羟基丁酸和/或其盐作为活性成分,并用于防止眼睛干燥和用于治疗泪液功能障碍的眼用组合物。 通过使用本发明的眼用组合物,可以抑制眼睛的干燥并且可以治疗泪液功能障碍。 因此,通过使用组合物,可以提高由泪液功能障碍引起的不适,例如眼睛干燥,异物感觉,眼睛不适和眼睛疲劳感。 此外,本发明的眼用组合物可以抑制由泪液功能障碍引起的疾病,例如发展与眼睛干燥有关的功能障碍的干眼症和怀疑干眼症,特别是由泪液功能障碍引起的疾病的发展, keratoconjunctive。

    ONE-PACK PREPARATION FOR DISINFECTION, NEUTRALIZATION AND CLEANING OF CONTACT LENSES AND METHOD OF DISINFECTION, NEUTRALIZATION AND CLEANING
    9.
    发明公开
    ONE-PACK PREPARATION FOR DISINFECTION, NEUTRALIZATION AND CLEANING OF CONTACT LENSES AND METHOD OF DISINFECTION, NEUTRALIZATION AND CLEANING 失效
    成分组成进行消毒,消毒,中和,中和清洗和隐形眼镜清洁和方法

    公开(公告)号:EP0923947A1

    公开(公告)日:1999-06-23

    申请号:EP97914593.5

    申请日:1997-04-03

    IPC分类号: A61L2/16 G02C13/00

    摘要: A preparation for simultaneously conducting disinfection, neutralization and cleaning of soft contact lenses, and a method for using easily, efficiently, and safely the preparation. The preparation comprises a combination of a first preparation containing an iodine disinfectant and a protease with a second preparation containing a reducing agent and a foaming agent and having a coating for delayed release, and a nonionic surfactant is contained in at least one of the first and second preparations. Soiled soft contact lenses are kept in an aqueous solution yellowed or browned with iodine molecules, and, after the aqueous solution has become substantially colorless, the lenses are separated from the aqueous solution, thus facilitating a series of procedures, that is, disinfection, neutralization, and cleaning.

    摘要翻译: 一种用于同时消毒进行,中和和清洁的软接触透镜的制备,以及使用便利,高效的方法,以及安全地制备。 该制剂包含的第一制备含碘消毒剂和具有第二制剂含有还原剂一种蛋白酶和一种发泡剂的并具有涂层对于延迟释放,和非离子表面活性剂的组合被包含在第一中的至少一个和 第二个准备。 弄脏软接触透镜在wässrige溶液变黄保持在或与碘分子褐色,并且,所述wässrige溶液变得基本上无色后,将镜片从wässrige溶液中分离出来,从而有利于一系列程序,所做的是,消毒,中和 和清洁。

    LIQUID PREPARATION FOR CONTACT LENSES COMPRISING HYDROLYZED HYALURONIC ACID DERIVATIVE AND CATIONIC BACTERICIDE

    公开(公告)号:EP3466448A1

    公开(公告)日:2019-04-10

    申请号:EP16903032.7

    申请日:2016-05-26

    摘要: The present invention relates to a liquid preparation for soft contact lenses, particularly hydrogel contact lenses or silicone hydrogel contact lenses.
    The liquid preparation for contact lenses according to the present invention contains a hydrolyzed hyaluronic acid derivative having a monoether of a linear or branched alkyl group or alkenyl group having 6 or more and 20 or less carbon atoms and glycerol in a side chain. The liquid preparation for soft contact lenses according to the present invention may contain at least one cationic bactericide selected from the group consisting of an alexidine salt, a chlorhexidine salt, a polyhexamethylene biguanide salt and a quaternary ammonium salt. The liquid preparation for soft contact lenses according to the present invention is capable of suppressing adsorption of a cationic bactericide to soft contact lenses, and suppressing occurrence of corneal staining in a wearer