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公开(公告)号：EP3774776A1
公开(公告)日：2021-02-17
申请号：EP19728645.3
申请日：2019-05-31
申请人： Qurient Co. Ltd.
发明人： NAM, Kiyean , KIM, Jaeseung , PARK, Dongsik , JEON, Yeejin , YANG, Yeong-In , KANG, Hwan Kyu
IPC分类号： C07D401/14 , C07D401/12 , A61P35/00 , A61K31/4709
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公开(公告)号：EP4255909A1
公开(公告)日：2023-10-11
申请号：EP21819125.2
申请日：2021-11-29
申请人： Qurient Co. Ltd.
发明人： NAM, Kiyean , KIM, Jaeseung , PARK, Dongsik , SEO, Mooyoung , JEON, Yeejin , YU, Donghoon
IPC分类号： C07D487/04 , C07F9/24 , A61K31/53 , A61K31/6615 , A61P9/00 , A61P31/00 , A61P35/00 , A61P37/00
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公开(公告)号：EP4003521A1
公开(公告)日：2022-06-01
申请号：EP19756324.0
申请日：2019-07-30
申请人： Qurient Co. Ltd.
发明人： NAM, Kiyean , KIM, Jaeseung , JUNG, Chunwon , LEE, Saeyeon
IPC分类号： A61P31/04 , A61P31/06 , C07D471/04 , A61K31/437
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4.发明公开TOPICAL ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITION WITH ZILEUTON CREAM FORMULATION 审中-公开TOPISCHEENTZÜNDUNGSHEMMENDEPHARMAZEUTISCHE ZUSAMMENSETZUNG MIT EINER ZILEUTON-CREMEFORMULIERUNG
公开(公告)号：EP3064197A4
公开(公告)日：2017-04-26
申请号：EP14858248
申请日：2014-08-13
申请人： QURIENT CO LTD
发明人： NAM KI YEAN , KIM JEONG JUN , OH SOO HYUN , LEE SAE YEON , AHN JI YE
CPC分类号： A61K9/0014 , A61K9/06 , A61K31/381 , A61K47/06 , A61K47/10 , A61K47/24 , A61K47/44
摘要： Provided herein is a zileuton cream type topical anti-inflammatory pharmaceutical composition, and more particularly, a zileuton cream type topical anti-inflammatory pharmaceutical composition capable of retaining stability at room temperature and of being applied topically to maximize medical effects while minimizing absorption to an entirety of body, thereby minimizing toxicity caused by the compound so as to be suitable to topical treatment of skin diseases caused by leukotriene.
摘要翻译： 本文提供了齐留通乳膏型局部抗炎药物组合物，并且更具体地，是能够在室温下保持稳定性并且局部应用以最大化医学效果同时最小化对整体的吸收的齐留通乳膏型局部抗炎性药物组合物 从而使化合物引起的毒性最小化，以适用于局部治疗由白三烯引起的皮肤病。
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公开(公告)号：EP4431114A3
公开(公告)日：2024-11-13
申请号：EP24176555.1
申请日：2020-12-17
申请人： Qurient Co. Ltd.
发明人： NAM, Kiyean , KIM, Jaeseung , JUNG, Chunwon , LEE, Saeyeon
IPC分类号： A61K31/437 , A61K9/28 , A61K47/38 , A61K47/32 , A61K47/26 , A61K9/20 , A61P31/04 , A61P31/06
摘要： The present invention relates to new pharmaceutical dosage forms of 6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phenyl)piperidine-1-yl)benzyl)imidazo[1,2-a]pyridine-3-carboxamide, in particular of its ditosylate form.
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公开(公告)号：EP3774809A1
公开(公告)日：2021-02-17
申请号：EP19720424.1
申请日：2019-04-11
发明人： NAM, Kiyean , KIM, Jaeseung , JEON, Yeejin , YU, Donghoon , SEO, Mooyoung , PARK, Dongsik , EICKHOFF, Jan , ZISCHINSKY, Gunther , KOCH, Uwe
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公开(公告)号：EP3286177B1
公开(公告)日：2020-05-06
申请号：EP16716247.8
申请日：2016-04-14
发明人： NAM, Kiyean , KIM, Jaeseung , AHN, Seohyun , JEON, Yeejin , LEE, Doohyung , PARK, Dongsik , YANG, Yeong-In , LEE, SaeYeon , KIM, Jeongjun , AHN, Jiye , KIM, Hana , JUNG, Chun-won , SCHULTZ-FADEMRECHT, Carsten
IPC分类号： C07D401/14 , C07D405/14 , C07D413/14 , C07D401/12 , C07D409/14 , C07D417/14 , A61K31/4709 , A61P35/00
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公开(公告)号：EP4431114A2
公开(公告)日：2024-09-18
申请号：EP24176555.1
申请日：2020-12-17
申请人： Qurient Co. Ltd.
发明人： NAM, Kiyean , KIM, Jaeseung , JUNG, Chunwon , LEE, Saeyeon
IPC分类号： A61K47/26
CPC分类号： A61K31/437 , A61K9/2866 , A61K47/38 , A61K47/32 , A61K47/26
摘要： The present invention relates to new pharmaceutical dosage forms of 6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phenyl)piperidine-1-yl)benzyl)imidazo[1,2-a]pyridine-3-carboxamide, in particular of its ditosylate form.
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公开(公告)号：EP3177597B1
公开(公告)日：2020-03-11
申请号：EP15748009.6
申请日：2015-07-31
发明人： KIM, Jaeseung , AHN, Seohyun , JEON, Yeejin , PARK, Dongsik , YANG, Young-In , LEE, Doohyung , LEE, SaeYeon , AHN, Jiye , KIM, Jeongjun , NAM, Kiyean , KANG, Sunhee , SEO, MinJung , SEO, Mooyoung , SEO, Jeongjea , HAN, Sung-Jun , KIM, Jung Hwan , LEE, Sangchul , CHOI, Gahee , LEE, Yunmi
IPC分类号： C07D235/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/14 , C07D471/04 , A61K31/4184
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公开(公告)号：EP3286177A1
公开(公告)日：2018-02-28
申请号：EP16716247
申请日：2016-04-14
发明人： NAM KIYEAN , KIM JAESEUNG , AHN SEOHYUN , JEON YEEJIN , LEE DOOHYUNG , PARK DONGSIK , YANG YOUNG-IN , LEE SAEYEON , KIM JEONGJUN , AHN JIYE , KIM HANA , JUNG CHUNG-WON , SCHULTZ-FADEMRECHT CARSTEN
IPC分类号： C07D401/14 , A61K31/4709 , A61P35/00 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
CPC分类号： C07D401/14 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要： The present invention relates to novel compounds which are inhibitors of TAM (Axl, Mer and Tyro 3) and/or Met family receptor tyrosine kinases (RTKs). These compounds are suitable for the treatment of disorders associated with, accompanied by, caused by or induced by a receptor of the TAM family, in particular a hyperfunction thereof. The compounds are suitable for the treatment of hyperproliferative disorders, such as cancer, particularly immune-suppressive cancer, refractory cancer and cancer metastases.
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