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公开(公告)号：EP2238482A1
公开(公告)日：2010-10-13
申请号：EP09703382.3
申请日：2009-01-21
CPC分类号： G02B1/043
摘要： An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent, wherein the ophthalmic device has an equilibrium water content of at least about 70 weight percent and further wherein the ophthalmic device has an evaporative dehydration barrier layer on the surface thereof. A method for the mitigation of evaporative corneal dehydration employing the high water content ophthalmic device is also disclosed.
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公开(公告)号：EP2066732A2
公开(公告)日：2009-06-10
申请号：EP07842642.6
申请日：2007-09-18
IPC分类号： C08G77/388 , C08L83/04 , G02B1/04
CPC分类号： C08G77/388 , A61L27/16 , A61L27/18 , C08G77/26 , G02B1/043 , C08L51/085 , C08L83/04
摘要： The present invention relates to hydrophilic dicationic siloxane prepolymers with at least one polymerizable vinyl moiety, resulting in contact lenses and/or biomedical devices with reduced cross-link density and modulus without detracting from other properties.
摘要翻译： 本发明涉及具有至少一个可聚合乙烯基部分的亲水性双阳离子硅氧烷预聚物，从而产生具有降低的交联密度和模量而不降低其它性能的隐形眼镜和/或生物医学装置。
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公开(公告)号：EP2035486B1
公开(公告)日：2012-04-25
申请号：EP07798170.2
申请日：2007-06-06
IPC分类号： C08G77/452 , C08G77/54
CPC分类号： C08G77/452 , C08G77/20 , C08G77/38 , G02B1/043 , C08L43/04 , C08L51/085
摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymer compositions comprise polymerized silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups.
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公开(公告)号：EP2231207A1
公开(公告)日：2010-09-29
申请号：EP08867880.0
申请日：2008-12-16
IPC分类号： A61L27/18 , C08J7/04 , C09D153/00 , G02B1/04
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , C08J7/047 , C08J2333/16 , C08J2383/10 , C08J2453/00 , C09D153/005 , C08L51/085 , C08L53/02
摘要： This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of interactive segmented block copolymers to the surface of the substrate by means of interactive functionalities of the segmented block copolymer reacting with complementary surface functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
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公开(公告)号：EP2222736A1
公开(公告)日：2010-09-01
申请号：EP08858010.5
申请日：2008-11-12
IPC分类号： C08F220/02 , C08F226/10 , G02B1/04
CPC分类号： C08F220/12 , C08F220/02 , C08F222/1006 , C08F230/08 , C08F2220/281 , G02B1/043 , Y10T428/31663 , C08L43/04 , C08L39/06
摘要： Silicone hydrogels formed from a hydrated polymerization product of a monomer mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; and (b) a minor amount of a silicone-containing monomer, wherein the hydrogel has a water content of greater than 50 weight percent are disclosed.
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公开(公告)号：EP2035485A2
公开(公告)日：2009-03-18
申请号：EP07812033.4
申请日：2007-06-06
IPC分类号： C08G77/388 , G02B1/04
CPC分类号： C08G77/388 , G02B1/043 , C08L43/04
摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain carboxylic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. The polymeric compositions comprise polymerized carboxylic hydrophilic siloxanyl monomers.
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7.发明授权MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME. 有权多臂大分子单体的聚合材料和隐形眼镜SO
公开(公告)号：EP2443483B1
公开(公告)日：2016-03-23
申请号：EP10724980.7
申请日：2010-06-14
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公开(公告)号：EP2443485A2
公开(公告)日：2012-04-25
申请号：EP10727307.0
申请日：2010-06-14
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , C08F20/56 , C08F26/08 , C08F118/02 , C08F226/02 , C08L81/00 , C08L83/10
摘要： Biomedical devices such as contact lenses formed from a comprising a polymerization product of a mixture comprising one or more ethylenically unsaturated-containing non- amphiphilic macromonomer comprising hydrophilic units or hydrophobic units derived from a living radical polymerization of one ore more ethylenically unsaturated hydrophilic monomers or one or more ethylenically unsaturated hydrophobic monomers are disclosed.
摘要翻译： 生物医学装置，例如由含有烯键式不饱和的非两亲性大分子单体的混合物的聚合产物形成的隐形眼镜，其包含亲水单元或衍生自一种或多种烯属不饱和亲水单体的活性自由基聚合的疏水单元或一种或多种烯属不饱和单体 公开疏水单体。
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9.发明公开MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME 有权多臂大分子单体的聚合材料和隐形眼镜SO
公开(公告)号：EP2443483A1
公开(公告)日：2012-04-25
申请号：EP10724980.7
申请日：2010-06-14
摘要： Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) one or more multi-armed macromonomers comprising multiple side chains attached to a nucleus, wherein each side chain comprises a thio carbonyl thio fragment of the same or different reversible addition fragmentation chain transfer ("RAFT") agent; and (b) one or more biomedical device-forming monomers are disclosed.
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公开(公告)号：EP2222736B1
公开(公告)日：2011-09-21
申请号：EP08858010.5
申请日：2008-11-12
IPC分类号： C08F220/02 , C08F226/10 , G02B1/04
CPC分类号： C08F220/12 , C08F220/02 , C08F222/1006 , C08F230/08 , C08F2220/281 , G02B1/043 , Y10T428/31663 , C08L43/04 , C08L39/06
摘要： Silicone hydrogels formed from a hydrated polymerization product of a monomer mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; and (b) a minor amount of a silicone-containing monomer, wherein the hydrogel has a water content of greater than 50 weight percent are disclosed.
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